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Disulfiram Transcends ALDH Inhibitory Activity When Targeting Ovarian Cancer Tumor-Initiating Cells

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Copper homeostasis and cuproptosis represent emerging targets for therapeutic intervention in inflammatory diseases

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Nanoscale Metal–Organic Frameworks and Nanoscale Coordination Polymers: From Synthesis to Cancer Therapy and Biomedical Imaging

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Photothermally Triggered Copper Payload Release for Cuproptosis‐Promoted Cancer Synergistic Therapy

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Disulfiram-loaded nanovesicles hydrogel promotes healing of diabetic wound

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Navigating Transition Metal‐Dependent Cell Death: Mechanisms, Crosstalk, and Future Directions

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Teaching new tricks to old dogs: A review of drug repositioning of disulfiram for cancer nanomedicine

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The immunomodulatory function and antitumor effect of disulfiram: paving the way for novel cancer therapeutics

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Overcoming the compensatory increase in NRF2 induced by NPL4 inhibition enhances disulfiram/copper-induced oxidative stress and ferroptosis in renal cell carcinoma

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The Promiscuity of Disulfiram in Medicinal Research

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Drug Repurposing in Oncology: Current Evidence and Future Direction

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Anti-proliferative activity of disulfiram through regulation of the AKT-FOXO axis: A proteomic study of molecular targets

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A phenotypic screening platform utilising human spermatozoa identifies compounds with contraceptive activity

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NIR-activatable proenzyme DSF/CuS@M for synergistic in situ chemotherapy/CDT/PTT/cuproptosis-based antitumor therapy

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Addressing misconceptions in dithiocarbamate chemistry

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Dextran-engineered Cu-MOF nanozyme with multi-enzyme mimetic cascade for cuproptosis-enhanced synergistic therapy in triple-negative breast cancer

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The interaction of disulfiram and H2S metabolism in inhibition of aldehyde dehydrogenase activity and liver cancer cell growth

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Molecular subtypes based on cuproptosis-related genes and tumor microenvironment infiltration characterization in ovarian cancer

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Disulfiram and copper combination therapy targets NPL4, cancer stem cells and extends survival in a medulloblastoma model

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Recent advances in copper homeostasis-involved tumor theranostics

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A drug repurposing strategy for overcoming human multiple myeloma resistance to standard-of-care treatment

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Targeting metalloptosis in tumor therapy: from molecular mechanisms to application of metal nanoparticles

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Augmenting MEK inhibitor efficacy in BRAF wild-type melanoma: synergistic effects of disulfiram combination therapy

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ALDH1A1 Gene Expression and Cellular Copper Levels between Low and Highly Metastatic Osteosarcoma Provide a Case for Novel Repurposing with Disulfiram and Copper

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Effect of Sepatronium Bromide (YM-155) on DNA Double-Strand Breaks Repair in Cancer Cells

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Isothiocyanates (ITCs) 1-(Isothiocyanatomethyl)-4-phenylbenzene and 1-Isothiocyanato-3,5-bis(trifluoromethyl)benzene—Aldehyde Dehydrogenase (ALDH) Inhibitors, Decreases Cisplatin Tolerance and Migratory Ability of NSCLC

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Polydopamine-Modified Copper Coordination Mesoporous Silica Nanoparticles Loaded with Disulfiram for Synergistic Chemo-Photothermal Therapy

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A Ferritin–Albumin–Cu Nanoparticle that Efficaciously Delivers Copper(II) Ions to a Tumor and Improves the Therapeutic Efficacy of Disulfiram

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Cannabidiol‐induced activation of the metallothionein pathway impedes anticancer effects of disulfiram and its metabolite CuET

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Killing hepatocellular carcinoma in the NAFLD/NASH stage: a comprehensive perspective on targeting regulated cell death

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A nanosystem of copper(II)-disulfiram for cancer treatment with high efficacy and few side effects

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Targeting emerging cancer hallmarks by transition metal complexes: Cancer stem cells and tumor microbiome. Part I

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Disulfiram and metformin combination anticancer effect reversible partly by antioxidant nitroglycerin and completely by NF-κB activator mebendazole in hamster fibrosarcoma

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Identification of novel dithiocarbamate-copper complexes targeting p97/NPL4 pathway in cancer cells

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Drug screening linked to molecular profiling identifies novel dependencies in patient-derived primary cultures of paediatric high grade glioma and DIPGPreprint

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Nuclear bodies protect phase separated proteins from degradation in stressed proteomePreprint

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The Emerging Roles of Aldehyde Dehydrogenase in Acute Myeloid Leukemia and Its Therapeutic Potential

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Revolutionizing breast cancer treatment: Harnessing the related mechanisms and drugs for regulated cell death (Review)

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The ALDH2/PolG2 axis enhances mitochondrial biogenesis via transcriptional regulation of Nrf2 and promotes chemotherapy resistance in acute myeloid leukaemia

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Possible Therapeutic Potential of Disulfiram for Multiple Myeloma

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The role of copper homeostasis and cuproptosis in cerebrovascular diseases:A novel therapeutic target

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Self-supplying Cu 2+ and H 2 O 2 synergistically enhancing disulfiram-mediated melanoma chemotherapy

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Disulfiram enhances the antitumor activity of cisplatin by inhibiting the Fanconi anemia repair pathway

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Programmable “triple attack” cancer therapy through in situ activation of disulfiram toxification combined with phototherapeutics

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DNA polymerase α/primase extraction from chromatin by VCP/p97 restricts ATR activation during unperturbed DNA replication

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Polatuzumab vedotin and CD79B : A study of efficacy in R‐CHOP‐resistant diffuse large B‐cell lymphoma

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Repurposing Disulfiram as a Chemo-Therapeutic Sensitizer: Molecular Targets and Mechanisms

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Disulfiram enhances chemotherapeutic effects of doxorubicin liposomes against human hepatocellular carcinoma via activating ROS-induced cell stress response pathways

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Proteomics Analysis Revealed Smad3 as a Potential Target of the Synergistic Antitumor Activity of Disulfiram and Cisplatin in Ovarian Cancer

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NPLOC4 is a potential target and a poor prognostic signature in lung squamous cell carcinoma

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Disulfiram activates autophagy via proteasome inhibition and c-Fos/beclin-1 upregulation, synergizing with chloroquine

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Ambivalent Copper: Mechanistically Distinct Immune Effects Driving Innovation in Cancer Nanomedicine

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Copper homeostasis and cuproptosis in cancer: mitochondrial metabolic dependency and nanomedicine-based therapeutic strategies

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Preparation of disulfiram-Cu2+-polylactide nanofibrous membranes via electrostatic spinning and evaluation of their in vitro anticancer effects

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Drug Repurposing for Targeting Cancer Stem-like Cells in Glioblastoma

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Quantitative proteomics analysis reveals novel insights into mechanisms of action of disulfiram (DSF)

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Drug Repurposing and DNA Damage in Cancer Treatment: Facts and Misconceptions

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Disulfiram';s Anticancer Activity: Evidence and Mechanisms

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Inhibitory effect on ovarian cancer ALDH+ stem-like cells by Disulfiram and Copper treatment through ALDH and ROS modulation

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Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4

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Repositioning an Old Anti-Alcoholism Drug: Disulfiram as a Selective, Effective and Economical Anticancer Agent

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Disulfiram (Antabuse) acts as a potent chemo-radio sensitizer and abolishes stem cells in HNSCC cell lines in vitro

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