The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
ASGR1: an emerging therapeutic target in hypercholesterolemia
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ASGR1 is essential for maintaining the balance between the production and degradation of circulating glycoproteins.
“However, inhibiting ASGR1 to enhance lipoprotein clearance may also pose risks as ASGR1 is essential for maintaining the balance between the production and degradation of circulating glycoproteins.”
From The low-density lipoprotein receptor: Emerging post-transcriptional regulatory mechanisms (2025) · cites this paper as [122]
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Citations
Cites
Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease
Nioi, P., Sigurdsson, A., Thorleifsson, G., Helgason, H., Agustsdottir, A. B., Norddahl, G. L., Helgadottir, A., Magnusdottir, A., Jonasdottir, A., Gretarsdottir, S., et al. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1508419 · Cited by 189
Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion
Wang, J.-Q., Li, L.-L., Hu, A., Deng, G., Wei, J., Li, Y.-F., Liu, Y.-B., Lu, X.-Y., Qiu, Z.-P., Shi, X.-J., et al. (2022) · Nature · doi:10.1038/s41586-022-05006-3 · Cited by 188
Hypomorphic ASGR1 modulates lipid homeostasis via INSIG1-mediated SREBP signaling suppression
Xu, Y., Tao, J., Yu, X., Wu, Y., Chen, Y., You, K., Zhang, J., Getachew, A., Pan, T., Zhuang, Y., et al. (2021) · JCI Insight · doi:10.1172/jci.insight.147038 · Cited by 45
Flagged first, then by citations
Research works printed but not linked: 2
- Hoober, J. K. ASGR1 and Its Enigmatic Relative, CLEC10A. Int. J. Mol. Sci. 21, 4818 (2020). · DOI · Paper page
- Xie, B. et al. Deficiency of ASGR1 in pigs recapitulates reduced risk factor for cardiovascular disease in humans. PLoS Genet. 17, e1009891 (2021). · DOI · Paper page
Cited by
Sorted by citations
The low-density lipoprotein receptor: Emerging post-transcriptional regulatory mechanisms
Ndoj, K., Meurs, A., Papaioannou, D., Bjune, K., & Zelcer, N. (2025) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2024.119082 · Cited by 17
Metadata
- Authors
- Zhao, W., Xu, S., & Weng, J.
- ORCID
- Weng, Jianping
- Venue
- Signal Transduction and Targeted Therapy
- Published
- 2023-01-23
- Volume
- 8
- Issue
- 1
- ISSN
- 2059-3635
- PMC
- PMC9869305
- Cited by
- 23
- References
- 3
- Language
- en
- Funders
- National Key R&D Program of China
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