The DOI matches its Crossref record; 96 of the 96 references it cites were found in a registry or an index.
The role of osteopontin in the progression of solid organ tumour
Open accessAbstract
Osteopontin (OPN) is a bone sialoprotein involved in osteoclast attachment to mineralised bone matrix, as well as being a bone matrix protein, OPN is also a versatile protein that acts on various receptors which are associated with different signalling pathways implicated in cancer. OPN mediates various biological events involving the immune system and the vascular system; the protein plays a role in processes such as immune response, cell adhesion and migration, and tumorigenesis. This review discusses the potential role of OPN in tumour cell proliferation, angiogenesis and metastasis, as well as the molecular mechanisms involved in these processes in different cancers, including brain, lung, kidney, liver, bladder, breast, oesophageal, gastric, colon, pancreatic, prostate and ovarian cancers. The understanding of OPN’s role in tumour development and progression could potentially influence cancer therapy and contribute to the development of novel anti-tumour treatments.
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Jemal, A., Bray, F., Center, M. M., Ferlay, J., Ward, E., & Forman, D. (2011) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.20107 · Cited by 54,679
Helicobacter pylori Infection and the Risk of Gastric Carcinoma
Parsonnet, J., Friedman, G. D., Vandersteen, D. P., Chang, Y., Vogelman, J. H., Orentreich, N., & Sibley, R. K. (1991) · New England Journal of Medicine · doi:10.1056/nejm199110173251603 · Cited by 3,894
The physics of cancer: the role of physical interactions and mechanical forces in metastasis
Wirtz, D., Konstantopoulos, K., & Searson, P. C. (2011) · Nature Reviews Cancer · doi:10.1038/nrc3080 · Cited by 1,344
Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment
Sui, X., Chen, R., Wang, Z., Huang, Z., Kong, N., Zhang, M., Han, W., Lou, F., Yang, J., Zhang, Q., et al. (2013) · Cell Death & Disease · doi:10.1038/cddis.2013.350 · Cited by 1,204
The role of STATs in transcriptional control and their impact on cellular function
Bromberg, J., & Darnell, J. E. (2000) · Oncogene · doi:10.1038/sj.onc.1203476 · Cited by 1,201
Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?
Chen, Q., Shou, P., Zheng, C., Jiang, M., Cao, G., Yang, Q., Cao, J., Xie, N., Velletri, T., Zhang, X., et al. (2016) · Cell Death & Differentiation · doi:10.1038/cdd.2015.168 · Cited by 1,156
Self-citationSodek, J., Ganss, B., & McKee, M. D. (2000) · Critical Reviews in Oral Biology & Medicine · doi:10.1177/10454411000110030101 · Cited by 993
Ye, Q.-H., Qin, L.-X., Forgues, M., He, P., Kim, J. W., Peng, A. C., Simon, R., Li, Y., Robles, A. I., Chen, Y., et al. (2003) · Nature Medicine · doi:10.1038/nm843 · Cited by 850
The role of nitric oxide in cancer
XU, W., LIU, L. Z., LOIZIDOU, M., AHMED, M., & CHARLES, I. G. (2002) · Cell Research · doi:10.1038/sj.cr.7290133 · Cited by 826
Osteopontin--a possible anchor of osteoclasts to bone.
Reinholt, F. P., Hultenby, K., Oldberg, A., & Heinegård, D. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.12.4473 · Cited by 824
Cited by
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Altered perivascular fibroblast activity precedes ALS disease onset
Månberg, A., Skene, N., Sanders, F., Trusohamn, M., Remnestål, J., Szczepińska, A., Aksoylu, I. S., Lönnerberg, P., Ebarasi, L., Wouters, S., et al. (2021) · Nature Medicine · doi:10.1038/s41591-021-01295-9 · Cited by 120
Harnessing Extracellular Matrix Biology for Tumor Drug Delivery
Subrahmanyam, N., & Ghandehari, H. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11020088 · Cited by 42
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Metadata
- Authors
- Zhao, H., Chen, Q., Alam, A., Cui, J., Suen, K. C., Soo, A. P., Eguchi, S., Gu, J., & Ma, D.
- Venue
- Cell Death & Disease
- Published
- 2018-03-02
- Volume
- 9
- Issue
- 3
- Pages
- 356-356
- ISSN
- 2041-4889 (ISSN-L)
- OpenAlex
- W2790339676
- Cited by
- 371
- References
- 96
- FWCI
- 23.30
- Type
- journal article
- Language
- en
- Open access
- gold
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- Zhao, H., Chen, Q., Alam, A., Cui, J., Suen, K. C., Soo, A. P., Eguchi, S., Gu, J., & Ma, D. (2018). The role of osteopontin in the progression of solid organ tumour. Cell Death & Disease. https://doi.org/10.1038/s41419-018-0391-6
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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