The DOI matches its Crossref record; 88 of the 88 references it cites were found in a registry or an index.
An update on the human and animal enteric pathogen Clostridium perfringens
Open accessAbstract
Clostridium perfringens, a rapid-growing pathogen known to secrete an arsenal of >20 virulent toxins, has been associated with intestinal diseases in both animals and humans throughout the past century. Recent advances in genomic analysis and experimental systems make it timely to re-visit this clinically and veterinary important pathogen. This Review will summarise our understanding of the genomics and virulence-linked factors, including antimicrobial potentials and secreted toxins of this gut pathogen, and then its up-to-date clinical epidemiology and biological role in the pathogenesis of several important human and animal-associated intestinal diseases, including pre-term necrotising enterocolitis. Finally, we highlight some of the important unresolved questions in relation to C. perfringens-mediated infections, and implications for future research directions.
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Cited by
Gut microbial molecules in behavioural and neurodegenerative conditions
Needham, B. D., Kaddurah-Daouk, R., & Mazmanian, S. K. (2020) · Nature Reviews Neuroscience · doi:10.1038/s41583-020-00381-0 · Cited by 379
Alshammari, M. K., AlKhulaifi, M. M., Al Farraj, D. A., Somily, A. M., & Albarrag, A. M. (2020) · Anaerobe · doi:10.1016/j.anaerobe.2019.102114 · Cited by 53
Cryo‐EM structure of the octameric pore of Clostridium perfringens β‐toxin
Bruggisser, J., Iacovache, I., Musson, S. C., Degiacomi, M. T., Posthaus, H., & Zuber, B. (2022) · The EMBO Reports · doi:10.15252/embr.202254856 · Cited by 13
Metadata
- Authors
- Kiu, R., & Hall, L. J.
- Venue
- Emerging Microbes & Infections
- Publisher
- Informa UK Limited
- Published
- 2018-08-06
- Volume
- 7
- Issue
- 1
- Pages
- 1-15
- ISSN
- 2222-1751 (ISSN-L)
- OpenAlex
- W2885835166
- Cited by
- 445
- References
- 88
- FWCI
- 23.69
- Type
- journal article
- Language
- en
- Open access
- gold
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- Kiu, R., & Hall, L. J. (2018). An update on the human and animal enteric pathogen Clostridium perfringens. Emerging Microbes & Infections. https://doi.org/10.1038/s41426-018-0144-8
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