The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Hydrogen peroxide positively regulates brassinosteroid signaling through oxidation of the BRASSINAZOLE-RESISTANT1 transcription factor
Open accessAbstract
Hydrogen peroxide (H 2 O 2) is an important signaling molecule in plant developmental processes and stress responses. However, whether H 2 O 2-mediated signaling crosstalks with plant hormone signaling is largely unclear. Here, we show that H 2 O 2 induces the oxidation of the BRASSINAZOLE-RESISTANT1 (BZR1) transcription factor, which functions as a master regulator of brassinosteroid (BR) signaling. Oxidative modification enhances BZR1 transcriptional activity by promoting its interaction with key regulators in the auxin-signaling and light-signaling pathways, including AUXIN RESPONSE FACTOR6 (ARF6) and PHYTOCHROME INTERACTING FACTOR4 (PIF4). Genome-wide analysis shows that H 2 O 2-dependent regulation of BZR1 activity plays a major role in modifying gene expression related to several BR-mediated biological processes. Furthermore, we show that the thioredoxin TRXh5 can interact with BZR1 and catalyzes its reduction. We conclude that reversible oxidation of BZR1 connects H 2 O 2-mediated and thioredoxin-mediated redox signaling to BR signaling to regulate plant development.
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Oxidative Modifications to Cellular Components in Plants
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Inducers of Plant Systemic Acquired Resistance Regulate NPR1 Function through Redox Changes
Mou, Z., Fan, W., & Dong, X. (2003) · Cell · doi:10.1016/s0092-8674(03)00429-x · Cited by 1,568
BRASSINOSTEROIDS: Essential Regulators of Plant Growth and Development
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Plant Immunity Requires Conformational Charges of NPR1 via S-Nitrosylation and Thioredoxins
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Self-citationInteraction between BZR1 and PIF4 integrates brassinosteroid and environmental responses
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Mechanisms of ROS Regulation of Plant Development and Stress Responses
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Metadata
- Authors
- Tian, Y., Fan, M., Qin, Z., Lv, H., Wang, M., Zhang, Z., Zhou, W., Zhao, N., Li, X., Han, C., Ding, Z., Wang, W., Wang, Z.-Y., & Bai, M.-Y.
- Venue
- Nature Communications
- Published
- 2018-03-14
- Volume
- 9
- Issue
- 1
- Pages
- 1063-1063
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W2792647569
- Cited by
- 265
- References
- 43
- FWCI
- 20.03
- Type
- journal article
- Language
- en
- Open access
- gold
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- Tian, Y., Fan, M., Qin, Z., Lv, H., Wang, M., Zhang, Z., Zhou, W., Zhao, N., Li, X., Han, C., Ding, Z., Wang, W., Wang, Z.-Y., & Bai, M.-Y. (2018). Hydrogen peroxide positively regulates brassinosteroid signaling through oxidation of the BRASSINAZOLE-RESISTANT1 transcription factor. Nature Communications. https://doi.org/10.1038/s41467-018-03463-x
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