The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Flavonoid intake is associated with lower mortality in the Danish Diet Cancer and Health Cohort
Open accessAbstract
Flavonoids, plant-derived polyphenolic compounds, have been linked with health benefits. However, evidence from observational studies is incomplete; studies on cancer mortality are scarce and moderating effects of lifestyle risk factors for early mortality are unknown. In this prospective cohort study including 56,048 participants of the Danish Diet, Cancer, and Health cohort crosslinked with Danish nationwide registries and followed for 23 years, there are 14,083 deaths. A moderate habitual intake of flavonoids is inversely associated with all-cause, cardiovascular- and cancer-related mortality. This strong association plateaus at intakes of approximately 500 mg/day. Furthermore, the inverse associations between total flavonoid intake and mortality outcomes are stronger and more linear in smokers than in non-smokers, as well as in heavy (>20 g/d) vs. low-moderate (<20 g/d) alcohol consumers. These findings highlight the potential to reduce mortality through recommendations to increase intakes of flavonoid-rich foods, particularly in smokers and high alcohol consumers.
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Self-citationFlavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women
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When do we need competing risks methods for survival analysis in nephrology?
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Cited by
Food as medicine: targeting the uraemic phenotype in chronic kidney disease
Mafra, D., Borges, N. A., Lindholm, B., Shiels, P. G., Evenepoel, P., & Stenvinkel, P. (2021) · Nature Reviews Nephrology · doi:10.1038/s41581-020-00345-8 · Cited by 238
Metadata
- Authors
- Bondonno, N. P., Dalgaard, F., Kyrø, C., Murray, K., Bondonno, C. P., Lewis, J. R., Croft, K. D., Gislason, G., Scalbert, A., Cassidy, A., Tjønneland, A., Overvad, K., & Hodgson, J. M.
- Venue
- Nature Communications
- Published
- 2019-08-13
- Volume
- 10
- Issue
- 1
- Pages
- 3651-3651
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W2968145135
- Cited by
- 322
- References
- 35
- FWCI
- 30.16
- Type
- journal article
- Language
- en
- Open access
- gold
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- Bondonno, N. P., Dalgaard, F., Kyrø, C., Murray, K., Bondonno, C. P., Lewis, J. R., Croft, K. D., Gislason, G., Scalbert, A., Cassidy, A., Tjønneland, A., Overvad, K., & Hodgson, J. M. (2019). Flavonoid intake is associated with lower mortality in the Danish Diet Cancer and Health Cohort. Nature Communications. https://doi.org/10.1038/s41467-019-11622-x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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