The DOI matches its Crossref record; 67 of the 67 references it cites were found in a registry or an index.
Tunable and functional deep eutectic solvents for lignocellulose valorization
Open accessAbstract
Stabilization of reactive intermediates is an enabling concept in biomass fractionation and depolymerization. Deep eutectic solvents (DES) are intriguing green reaction media for biomass processing; however undesired lignin condensation is a typical drawback for most acid-based DES fractionation processes. Here we describe ternary DES systems composed of choline chloride and oxalic acid, additionally incorporating ethylene glycol (or other diols) that provide the desired ‘stabilization’ function for efficient lignocellulose fractionation, preserving the quality of all lignocellulose constituents. The obtained ethylene-glycol protected lignin displays high β-O-4 content (up to 53 per 100 aromatic units) and can be readily depolymerized to distinct monophenolic products. The cellulose residues, free from condensed lignin particles, deliver up to 95.9 ± 2.12% glucose yield upon enzymatic digestion. The DES can be recovered with high yield and purity and re-used with good efficiency. Notably, we have shown that the reactivity of the β-O-4 linkage in model compounds can be steered towards either cleavage or stabilization, depending on DES composition, demonstrating the advantage of the modular DES composition.
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Cites
Deep Eutectic Solvents (DESs) and Their Applications
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Deep eutectic solvents: syntheses, properties and applications
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Bright Side of Lignin Depolymerization: Toward New Platform Chemicals
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Self-citationDeconstruction of lignocellulosic biomass with ionic liquids
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Formaldehyde stabilization facilitates lignin monomer production during biomass depolymerization
Shuai, L., Amiri, M. T., Questell-Santiago, Y. M., Héroguel, F., Li, Y., Kim, H., Meilan, R., Chapple, C., Ralph, J., & Luterbacher, J. S. (2016) · Science · doi:10.1126/science.aaf7810 · Cited by 1,404
A sustainable wood biorefinery for low–carbon footprint chemicals production
Liao, Y., Koelewijn, S.-F., Van den Bossche, G., Van Aelst, J., Van den Bosch, S., Renders, T., Navare, K., Nicolaï, T., Van Aelst, K., Maesen, M., et al. (2020) · Science · doi:10.1126/science.aau1567 · Cited by 1,126
Van den Bosch, S., Schutyser, W., Vanholme, R., Driessen, T., Koelewijn, S.-F., Renders, T., De Meester, B., Huijgen, W. J. J., Dehaen, W., Courtin, C. M., et al. (2015) · Energy & Environmental Science · doi:10.1039/c5ee00204d · Cited by 896
Evaluation of toxicity and biodegradability of choline chloride based deep eutectic solvents
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Cited by
Wang, J., Bao, F., Wei, H., & Zhang, Y. (2024) · Scientific Reports · doi:10.1038/s41598-024-58540-7 · Cited by 47
Song, X., Guo, W., Zhu, Z., Han, G., & Cheng, W. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.128827 · Cited by 18
Metadata
- Authors
- Liu, Y., Deak, N., Wang, Z., Yu, H., Hameleers, L., Jurak, E., Deuss, P. J., & Barta, K.
- Venue
- Nature Communications
- Published
- 2021-09-14
- Volume
- 12
- Issue
- 1
- Pages
- 5424-5424
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W3199527194
- Cited by
- 452
- References
- 67
- FWCI
- 16.31
- Type
- journal article
- Language
- en
- Open access
- gold
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- Liu, Y., Deak, N., Wang, Z., Yu, H., Hameleers, L., Jurak, E., Deuss, P. J., & Barta, K. (2021). Tunable and functional deep eutectic solvents for lignocellulose valorization. Nature Communications. https://doi.org/10.1038/s41467-021-25117-1
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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