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Cited by 530

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Etiological and epidemiological features of acute respiratory infections in China

Open access
Li, Zhong-Jie, Zhang, Hai-Yang, Ren, Li-Li, Lu, Qing-Bin, Ren, Xiang, Zhang, Cui-Hong, Wang, Yi-Fei, Lin, Sheng-Hong, Zhang, Xiao-Ai, Li, Jun, Zhao, Shi-Wen, Yi, Zhi-Gang, Chen, Xiao, Yang, Zuo-Sen, Meng, Lei, Wang, Xin-Hua, Liu, Ying-Le, Wang, Xin, Cui, Ai-Li, Lai, Sheng-Jie, Jiang, Tao, Yuan, Yang, Shi, Lu-Sha, Liu, Meng-Yang, Zhu, Yu-Liang, Zhang, An-Ran, Zhang, Zhi-Jie, Yang, Yang, Ward, Michael P., Feng, Lu-Zhao, Jing, Huai-Qi, Huang, Liu-Yu, Xu, Wen-Bo, Chen, Yu, Wu, Jian-Guo, Yuan, Zheng-Hong, Li, Meng-Feng, Wang, Yu, Wang, Li-Ping, Fang, Li-Qun, Liu, Wei, Hay, Simon I., Gao, George F., Yang, Wei-Zhong, The Chinese Centers for Disease Control and Prevention (CDC) Etiology of Respiratory Infection Surveillance Study Team, Yang, Wei-Zhong, Gao, George F., Li, Zhong-Jie, Wang, Li-Ping, Ren, Xiang, Wang, Yi-Fei, Lin, Sheng-Hong, Zhang, Cui-Hong, Geng, Meng-Jie, Wang, Xin, Jing, Huai-Qi, Xu, Wen-Bo, Cui, Ai-Li, Shen, Yu-Juan, Jiang, Yan-Yan, Sun, Qiao, Hao, Li-Peng, Ye, Chu-Chu, Liu, Wei, Zhang, Xiao-Ai, Huang, Liu-Yu, Wang, Yong, Zhang, Wen-Yi, Zhang, Qi, Liu, Wei-Yong, Sun, Zi-Yong, Zhan, Fa-Xian, Xiong, Ying, Yu, De-Shan, Wang, Chun-Xiang, Zhao, Sheng-Cang, Wang, Wen-Rui, Lei, Xia, Li, Juan-Sheng, Wang, Yu-Hong, Zhang, Yan, Yang, Jun-Peng, Wang, Yan-Bo, Quan, Fu-Cai, Xiong, Zhi-Jun, Liang, Li-Ping, Chang, Quan-E, Wang, Yun, Wang, Ping, Mao, Ling-Ling, Li, Jia-Meng, Lv, Li-Kun, Xu, Jun, Shu, Chang, Chen, Xiao, Chen, Yu, Zhang, Yan-Jun, Cui, Lun-Biao, Zheng, Kui-Cheng, Zhang, Xing-Guo, Zhang, Xi, Tu, Li-Hong, Wang, Wei, Zhou, Xiao-Fang, Pei, Xiao-Fang, Zheng, Tian-Li, Zhong, Xiao-Ni, Li, Qin, Ling, Hua, Wang, Ding-Ming, Li, Shi-Jun, He, Shu-Sen, Zhu, Xun, Ke, Chang-Wen, Xiao, Hong, Di, Biao, Zhang, Ying, Zhou, Hong-Wei, Yu, Nan, Li, Hong-Jian, Yang, Fang, Wang, Fu-Xiang, Wang, Jun·2021·Nature Communications

Abstract

Nationwide prospective surveillance of all-age patients with acute respiratory infections was conducted in China between 2009‒2019. Here we report the etiological and epidemiological features of the 231,107 eligible patients enrolled in this analysis. Children <5 years old and school-age children have the highest viral positivity rate (46.9%) and bacterial positivity rate (30.9%). Influenza virus, respiratory syncytial virus and human rhinovirus are the three leading viral pathogens with proportions of 28.5%, 16.8% and 16.7%, and Streptococcus pneumoniae, Mycoplasma pneumoniae and Klebsiella pneumoniae are the three leading bacterial pathogens (29.9%, 18.6% and 15.8%). Negative interactions between viruses and positive interactions between viral and bacterial pathogens are common. A Join-Point analysis reveals the age-specific positivity rate and how this varied for individual pathogens. These data indicate that differential priorities for diagnosis, prevention and control should be highlighted in terms of acute respiratory tract infection patients’ demography, geographic locations and season of illness in China.

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Authors
Li, Z.-J., Zhang, H.-Y., Ren, L.-L., Lu, Q.-B., Ren, X., Zhang, C.-H., Wang, Y.-F., Lin, S.-H., Zhang, X.-A., Li, J., Zhao, S.-W., Yi, Z.-G., Chen, X., Yang, Z.-S., Meng, L., Wang, X.-H., Liu, Y.-L., Wang, X., Cui, A.-L., Lai, S.-J., Jiang, T., Yuan, Y., Shi, L.-S., Liu, M.-Y., Zhu, Y.-L., Zhang, A.-R., Zhang, Z.-J., Yang, Y., Ward, M. P., Feng, L.-Z., Jing, H.-Q., Huang, L.-Y., Xu, W.-B., Chen, Y., Wu, J.-G., Yuan, Z.-H., Li, M.-F., Wang, Y., Wang, L.-P., Fang, L.-Q., Liu, W., Hay, S. I., Gao, G. F., Yang, W.-Z., The Chinese Centers for Disease Control and Prevention (CDC) Etiology of Respiratory Infection Surveillance Study Team, Yang, W.-Z., Gao, G. F., Li, Z.-J., Wang, L.-P., Ren, X., Wang, Y.-F., Lin, S.-H., Zhang, C.-H., Geng, M.-J., Wang, X., Jing, H.-Q., Xu, W.-B., Cui, A.-L., Shen, Y.-J., Jiang, Y.-Y., Sun, Q., Hao, L.-P., Ye, C.-C., Liu, W., Zhang, X.-A., Huang, L.-Y., Wang, Y., Zhang, W.-Y., Zhang, Q., Liu, W.-Y., Sun, Z.-Y., Zhan, F.-X., Xiong, Y., Yu, D.-S., Wang, C.-X., Zhao, S.-C., Wang, W.-R., Lei, X., Li, J.-S., Wang, Y.-H., Zhang, Y., Yang, J.-P., Wang, Y.-B., Quan, F.-C., Xiong, Z.-J., Liang, L.-P., Chang, Q.-E., Wang, Y., Wang, P., Mao, L.-L., Li, J.-M., Lv, L.-K., Xu, J., Shu, C., Chen, X., Chen, Y., Zhang, Y.-J., Cui, L.-B., Zheng, K.-C., Zhang, X.-G., Zhang, X., Tu, L.-H., Wang, W., Zhou, X.-F., Pei, X.-F., Zheng, T.-L., Zhong, X.-N., Li, Q., Ling, H., Wang, D.-M., Li, S.-J., He, S.-S., Zhu, X., Ke, C.-W., Xiao, H., Di, B., Zhang, Y., Zhou, H.-W., Yu, N., Li, H.-J., Yang, F., Wang, F.-X., & Wang, J.
Venue
Nature Communications
Published
2021-08-18
Volume
12
Issue
1
Pages
5026-5026
ISSN
2041-1723 (ISSN-L)
OpenAlex
W3194441010
Cited by
530
References
5
FWCI
36.00
Type
journal article
Language
en
Open access
gold

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Li, Z.-J., Zhang, H.-Y., Ren, L.-L., Lu, Q.-B., Ren, X., Zhang, C.-H., Wang, Y.-F., Lin, S.-H., Zhang, X.-A., Li, J., Zhao, S.-W., Yi, Z.-G., Chen, X., Yang, Z.-S., Meng, L., Wang, X.-H., Liu, Y.-L., Wang, X., Cui, A.-L., . . . Wang, J. (2021). Etiological and epidemiological features of acute respiratory infections in China. Nature Communications. https://doi.org/10.1038/s41467-021-25120-6

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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