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Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

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Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile

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Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

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Colorectal cancer–associated T cell receptor repertoire abnormalities are linked to gut microbiome shifts and somatic cell mutations

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Novel therapeutic strategies and recent advances in gut microbiota synergy with nanotechnology for colorectal cancer treatment

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Dietary Modulation of Bacteriophages as an Additional Player in Inflammation and Cancer

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A seed-like hydrogel with metabolic cascade microbiota for oral treatment of liver failure

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Host mRNA Analysis of Periodontal Disease Patients Positive for Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans and Tannerella forsythia

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Improving the safety and efficacy of phage therapy from the perspective of phage-mammal interactions

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Gut microbiome associated dysbiosis: Limited regimens and expanding horizons of phage therapy

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Gut microbiota and immunosenescence in cancer

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Microbes Saving Lives and Reducing Suffering

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Microrobotic Swarms for Cancer Therapy

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Biomimetic “Trojan Horse” nanoparticles with biotactic behavior toward tumor-associated bacteria for targeted therapy of colorectal cancer

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Phage–nanomaterial platforms for precision antimicrobial therapy: from design to therapeutic application

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Lactiplantibacillus plantarum HNU082 inhibited the growth of Fusobacterium nucleatum and alleviated the inflammatory response introduced by F. nucleatum invasion

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The Microbiome in Pancreatic Cancer-Implications for Diagnosis and Precision Bacteriophage Therapy for This Low Survival Disease

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Parvimonas micra can translocate from the subgingival sulcus of the human oral cavity to colorectal adenocarcinoma

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Blocking Fusobacterium nucleatum-host cell interactions with responsive supramolecular GalNAc-derived nanoplatform for enhanced chemotherapy in colorectal cancer

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Advancements in colorectal cancer treatment: The role of metal-based and inorganic nanoparticles in modern therapeutic approaches

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Targeted Elimination of the Oral Pathogen to Overcome Chemoresistance of Oral Squamous Cell Carcinoma by Biologically Derived Nanotherapeutics

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The Emerging Roles of Human Gut Microbiota in Gastrointestinal Cancer

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Potential of bacteriophage therapy in managing Staphylococcus aureus infections during chemotherapy for lung cancer patients

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Cascade Catalytic Nanoparticles Selectively Alkalize Cancerous Lysosomes to Suppress Cancer Progression and Metastasis

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Late-Stage Functionalization of Living Organisms: Rethinking Selectivity in Biology

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Unveiling the hidden players: exploring the role of gut mycobiome in cancer development and treatment dynamics

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Role of gut microbiome in regulating the effectiveness of metformin in reducing colorectal cancer in type 2 diabetes

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Sendai virus-based immunoadjuvant in hydrogel vaccine intensity-modulated dendritic cells activation for suppressing tumorigenesis

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Targeting the Tumor Microbiota in Cancer Therapy Basing on Nanomaterials

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Recent Progress in Phage‐Based Nanoplatforms for Tumor Therapy

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Bacteria-nanodrug cancer treatment system: The combination of dual swords and the confrontation of needle tips

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Interaction between gut microbiota and T cell immunity in colorectal cancer

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Using tea nanoclusters as β-lactamase inhibitors to cure multidrug-resistant bacterial pneumonia: A promising therapeutic strategy by Chinese materioherbology

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Progress of tumor-resident intracellular bacteria for cancer therapy

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Applications of bacteriophages in precision engineering of the human gut microbiome

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Engineering bacteriophages for gut health: precision antimicrobials and beyond

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Phage therapy in gut microbiome

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Remotely Controllable Supramolecular Nanomedicine for Drug‐Resistant Colorectal Cancer Therapy Caused by Fusobacterium nucleatum

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Fusobacterium nucleatum: a novel regulator of antitumor immune checkpoint blockade therapy in colorectal cancer

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Effects of intratumoral microbiota on tumorigenesis, anti-tumor immunity, and microbe-based cancer therapy

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Emerging insights into the gut microbiota as a key regulator of immunity and response to immunotherapy in hepatocellular carcinoma

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Phages Enter the Fight against Colorectal Cancer

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The Viral Janus: Viruses as Aetiological Agents and Treatment Options in Colorectal Cancer

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Microbial manipulators: Fusobacterium nucleatum modulates the tumor immune microenvironment in colorectal cancer

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Advancement in Therapeutic Intervention of Prebiotic-Based Nanoparticles for Colonic Diseases

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Exploring phage engineering to advance nanobiotechnology

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An intratumor bacteria-targeted DNA nanocarrier for multifaceted tumor microenvironment intervention

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Fusobacterium nucleatum in Colorectal Cancer: Ally Mechanism and Targeted Therapy Strategies

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Microbiota and cancer: In vitro and in vivo models to evaluate nanomedicines

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Research advances in nanomedicine applied to the systemic treatment of colorectal cancer

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Tumor-Targeting Nanoassembly for Enhanced Colorectal Cancer Therapy by Eliminating Intratumoral Fusobacterium nucleatum

Li, X., Ma, Y., Xin, Y., Ma, F., & Gao, H. (2023) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c01210 · Cited by 17

The intratumoral microbiota in breast cancer: from basic research to clinical translation

Xu, Y., & Wang, M. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2560695 · Cited by 16

Engineered Bacteria-Nano Hybrid System: The Intelligent Drug Factory for Next-Generation Cancer Immunotherapy

Zi, G., Zhou, W., Zhou, L., Wang, L., Zheng, P., & Wei, S. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17101349 · Cited by 16

Mechanistic insights into the interaction between the host gut microbiome and malaria

Mandal, R. K., & Schmidt, N. W. (2023) · PLoS Pathogens · doi:10.1371/journal.ppat.1011665 · Cited by 16

Correlation of gut microbiota with leukopenia after chemotherapy in patients with colorectal cancer

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Targeting bacterial metabolites in tumor for cancer therapy: An alternative approach for targeting tumor-associated bacteria

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Harnessing and Mimicking Bacterial Features to Combat Cancer: From Living Entities to Artificial Mimicking Systems

Gao, P., Duan, Z., Xu, G., Gong, Q., Wang, J., Luo, K., & Chen, J. (2024) · Advanced Materials · doi:10.1002/adma.202405075 · Cited by 16

Living Biomaterials: Fabrication Strategies and Biomedical Applications

Chen, Q., & Zhang, X. (2024) · Accounts of Materials Research · doi:10.1021/accountsmr.4c00258 · Cited by 16

Gut microbiota — bidirectional modulator: role in inflammatory bowel disease and colorectal cancer

Cui, X., Li, C., Zhong, J., Liu, Y., Xiao, P., Liu, C., Zhao, M., & Yang, W. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1523584 · Cited by 16

Tailoring a Functional Synthetic Microbial Community Alleviates Fusobacterium nucleatum‐infected Colorectal Cancer via Ecological Control

Zhou, Z., Yang, M., Fang, H., Zhang, B., Ma, Y., Li, Y., Liu, Y., Cheng, Z., Zhao, Y., Si, Z., et al. (2025) · Advanced Science · doi:10.1002/advs.202414232 · Cited by 16

Viruses as biomaterials

Yang, T., Chen, Y., Xu, Y., Liu, X., Yang, M., & Mao, C. (2023) · Materials Science and Engineering R Reports · doi:10.1016/j.mser.2023.100715 · Cited by 16

Establishment of an Endoscopy-Guided Minimally Invasive Orthotopic Mouse Model of Colorectal Cancer

Chen, C., Neumann, J. H. L., Kühn, F., Lee, S. M. L., Drefs, M., Andrassy, J., Werner, J., Bazhin, A. V., & Schiergens, T. S. (2020) · Cancers · doi:10.3390/cancers12103007 · Cited by 16

Inhibiting PI3K/AKT/mTOR signaling by metal-organic frameworks for overcoming multiple drug resistance in chemoradiotherapy

Song, C., Guan, X., Xie, C., Jiang, S., Hong, Z., Wu, Q., Qu, G., Ma, T., & Cui, Y. (2024) · Science China Materials · doi:10.1007/s40843-023-2774-8 · Cited by 15

Curcumin-Modified Selenium Nanoparticles Improve S180 Tumour Therapy in Mice by Regulating the Gut Microbiota and Chemotherapy

Zhang, R., Zhang, W., Zhang, Q., Wang, L., Yang, F., Sun, W., Xu, Z., Wang, C., Song, X., & Wang, M. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s476686 · Cited by 15

Milk microbial composition of Brazilian dairy cows entering the dry period and genomic comparison between Staphylococcus aureus strains susceptible to the bacteriophage vB_SauM-UFV_DC4

Duarte, V. D. S., Treu, L., Sartori, C., Dias, R. S., Paes, I. D. S., Vieira, M. S., Santana, G. R., Marcondes, M. I., Giacomini, A., Corich, V., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-62499-6 · Cited by 15

The Microbiome in PDAC—Vantage Point for Future Therapies?

Pfisterer, N., Lingens, C., Heuer, C., Dang, L., Neeße, A., & Ammer‐Herrmenau, C. (2022) · Cancers · doi:10.3390/cancers14235974 · Cited by 15

Gut Phage Biobank: a collection of bacteriophages targeting human commensal bacteria

Xing, B., Liu, C., Chen, W., Li, Z., Jing, X., Wu, C., Liu, R., Zhang, X., Xu, X., Li, J., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-61946-0 · Cited by 14

Gut microbiota in cancer: insights on microbial metabolites and therapeutic strategies

Chen, Y., Wang, X., Ye, Y., & Ren, Q. (2023) · Medical Oncology · doi:10.1007/s12032-023-02249-6 · Cited by 14

Recent Progress of Oral Functional Nanomaterials for Intestinal Microbiota Regulation

Li, W., Zhan, M., Wen, Y., Chen, Y., Zhang, Z., Wang, S., Tian, D., & Tian, S. (2024) · Pharmaceutics · doi:10.3390/pharmaceutics16070921 · Cited by 14

Advances in Engineered Phages for Disease Treatment

Hou, X. L., Lin, Z., Fu, L., Lu, J., Guo, P., Zhang, Y., Zheng, D., & Ma, G. (2025) · Small Methods · doi:10.1002/smtd.202401611 · Cited by 14

Targeting Intratumoral Bacteria for Cancer Treatment

Shi, J., Liang, J., Li, Y., Zhang, Z., Sun, J. X., He, Z., Luo, C., Qu, X., Che, X., & Zhang, S. (2025) · Small · doi:10.1002/smll.202505651 · Cited by 14

Bacteriophages: cancer diagnosis, treatment, and future prospects

Abbaszadeh, F., Leylabadlo, H. E., Alinezhad, F., Feizi, H., Mobed, A., Baghbanijavid, S., & Baghi, H. B. (2020) · Journal of Pharmaceutical Investigation · doi:10.1007/s40005-020-00503-x · Cited by 14

What is unknown in using microbiota as a therapeutic?

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Intratumoral microorganisms in tumors of the digestive system

Xuan, M., Gu, X., Liu, Y., Li, Y., Li, Y., Huang, D., Li, J., & Xue, C. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-023-01425-5 · Cited by 13

Emerging implications of bacterial biofilm in cancer biology: Recent updates and major perspectives

Kushwaha, M., Nukala, V., Singh, A. K., Makharia, G. K., Mohan, A., Kumar, A., & Dalal, N. (2024) · Gut Microbes Reports · doi:10.1080/29933935.2024.2339270 · Cited by 13

Neutrophils in the Focus: Impact on Neuroimmune Dynamics and the Gut–Brain Axis

Kršek, A., & Batičić, L. (2024) · Gastrointestinal Disorders · doi:10.3390/gidisord6030039 · Cited by 13

Leveraging the intratumoral microbiota to treat human cancer: are engineered exosomes an effective strategy?

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Elucidating the genotoxicity of Fusobacterium nucleatum-secreted mutagens in colorectal cancer carcinogenesis

Xu, W., Zhang, Y., Chen, D.-J., Huang, D., Zhao, Y., Hu, W., Lin, L., Liu, Y., Wang, S., Zeng, J., et al. (2024) · Gut Pathogens · doi:10.1186/s13099-024-00640-w · Cited by 13

Adhesin RadD: the secret weapon of Fusobacterium nucleatum

Jia, D., & Chen, S. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2426617 · Cited by 13

Strategies for engineering biomimetic materials for tumor therapy

Ma, Z., Zhang, K., & Zhao, Y. (2025) · Matter · doi:10.1016/j.matt.2024.10.017 · Cited by 13

Unveiling the intratumor microbiome in liver cancer: Current insights and prospective applications

Ke, X., Jiang, S., Wei, Q., Sun, M., Sun, H., Pang, M., Liu, M., Sun, L., Yang, H., & Mao, Y. (2025) · Clinical and Molecular Hepatology · doi:10.3350/cmh.2024.1039 · Cited by 13

Engineered bacteria for cancer therapy: synergistic innovations in synthetic biology and materials science

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Nano drug delivery systems improve metastatic breast cancer therapy

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Integration of genetically engineered virus nanofibers and fibrin to form injectable fibrous neuron-rich hydrogels and enable neural differentiation

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The colorectal cancer-specific microbiome regulation and immune response activation via an artificial biomimetic nanovaccine

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The role of gut microbiota and drug interactions in the development of colorectal cancer

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