The DOI matches its Crossref record; 85 of the 85 references it cites were found in a registry or an index.
Salmonella enterica genomes from victims of a major sixteenth-century epidemic in Mexico
Open accessAbstract
Indigenous populations of the Americas experienced high mortality rates during the early contact period as a result of infectious diseases, many of which were introduced by Europeans. Most of the pathogenic agents that caused these outbreaks remain unknown. Through the introduction of a new metagenomic analysis tool called MALT, applied here to search for traces of ancient pathogen DNA, we were able to identify Salmonella enterica in individuals buried in an early contact era epidemic cemetery at Teposcolula-Yucundaa, Oaxaca in southern Mexico. This cemetery is linked, based on historical and archaeological evidence, to the 1545–1550 ce epidemic that affected large parts of Mexico. Locally, this epidemic was known as ‘cocoliztli’, the pathogenic cause of which has been debated for more than a century. Here, we present genome-wide data from ten individuals for Salmonella enterica subsp. enterica serovar Paratyphi C, a bacterial cause of enteric fever. We propose that S. Paratyphi C be considered a strong candidate for the epidemic population decline during the 1545 cocoliztli outbreak at Teposcolula-Yucundaa.Ancient DNA from victims of a sixteenth-century disease in Mexico suggests that Salmonella enterica Paratyphi C (enteric fever) was responsible for a devastating epidemic that closely followed European presence in the region.
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Cited by
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Self-citationAncient pathogen genomics as an emerging tool for infectious disease research
Spyrou, M. A., Bos, K. I., Herbig, A., & Krause, J. (2019) · Nature Reviews Genetics · doi:10.1038/s41576-019-0119-1 · Cited by 285
Self-citationSpyrou, M. A., Keller, M., Tukhbatova, R. I., Scheib, C. L., Nelson, E. A., Andrades Valtueña, A., Neumann, G. U., Walker, D., Alterauge, A., Carty, N., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12154-0 · Cited by 182
Self-citationKeller, M., Spyrou, M. A., Scheib, C. L., Neumann, G. U., Kröpelin, A., Haas-Gebhard, B., Päffgen, B., Haberstroh, J., Ribera i Lacomba, A., Raynaud, C., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1820447116 · Cited by 156
Self-citationHOPS: automated detection and authentication of pathogen DNA in archaeological remains
Hübler, R., Key, F. M., Warinner, C., Bos, K. I., Krause, J., & Herbig, A. (2019) · Genome Biology · doi:10.1186/s13059-019-1903-0 · Cited by 141
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Metadata
- Authors
- Vågene, Å. J., Herbig, A., Campana, M. G., Robles García, N. M., Warinner, C., Sabin, S., Spyrou, M. A., Andrades Valtueña, A., Huson, D., Tuross, N., Bos, K. I., & Krause, J.
- Venue
- Nature Ecology & Evolution
- Published
- 2018-01-15
- Volume
- 2
- Issue
- 3
- Pages
- 520-528
- ISSN
- 2397-334X (ISSN-L)
- OpenAlex
- W2784010265
- Cited by
- 316
- References
- 85
- FWCI
- 261.73
- Type
- journal article
- Language
- en
- Open access
- green
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- Vågene, Å. J., Herbig, A., Campana, M. G., Robles García, N. M., Warinner, C., Sabin, S., Spyrou, M. A., Andrades Valtueña, A., Huson, D., Tuross, N., Bos, K. I., & Krause, J. (2018). Salmonella enterica genomes from victims of a major sixteenth-century epidemic in Mexico. Nature Ecology & Evolution. https://doi.org/10.1038/s41559-017-0446-6
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