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Quercetin boosts gut microbiota-driven production of isovanillic acid to alleviate colitis via enhancing intestinal barrier function

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Integrated Macrogenomics and Metabolomics Explore Alterations and Correlation between Gut Microbiota and Serum Metabolites in Adult Epileptic Patients: A Pilot Study

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The altered TBI fecal microbiome is stable and functionally distinct

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Polygonatum cyrtonema polysaccharides reshape the gut microbiota to ameliorate dextran sodium sulfate-induced ulcerative colitis in mice

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Gas-propelled nanomotors alleviate colitis through the regulation of intestinal immunoenvironment-hematopexis-microbiota circuits

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Review and revamp of compositional data transformation: A new framework combining proportion conversion and contrast transformation

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Vagus nerve and brain–gut communication in neurodegenerative diseases: Mechanism and therapeutic perspectives

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Parasutterella excrementihominis exacerbates experimental colitis and colitis-associated colorectal cancer via pathogenic NETosis activation

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Using the Microbiome as a Regenerative Medicine Strategy for Autoimmune Diseases

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An ROS/DAMP dual-scavenging nanomedicine for normalizing macrophage polarization and microbiome in colitis

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Function-based selection of synthetic communities enables mechanistic microbiome studies

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Epigenetic regulation and therapeutic strategies in ulcerative colitis

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Lupus and inflammatory bowel disease share a common set of microbiome features distinct from other autoimmune disorders

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Impact of commercial gut health interventions on caecal metagenome and broiler performance

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OTUD3 prevents ulcerative colitis by inhibiting microbiota-mediated STING activation

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Microbial and Immune Regulation of the Gut-Lung Axis during Viral-Bacterial Coinfection

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Peimisine ameliorates DSS-induced colitis by suppressing Jak–Stat activation and alleviating gut microbiota dysbiosis in mice

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Cold-tolerance mechanisms in foodborne pathogens: Escherichia coli and Listeria monocytogenes as examples

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Microbial Signatures in COVID-19: Distinguishing Mild and Severe Disease via Gut Microbiota

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The impact of Astragaloside IV on the inflammatory response and gut microbiota in cases of acute lung injury is examined through the utilization of the PI3K/AKT/mTOR pathway

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Emerging concepts and shifting paradigms for understanding the microbial basis of inflammatory bowel diseases

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A Bacteroides fragilis protease activates host PAR2 to induce intestinal pain and inflammation

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Harnessing human microbiomes for disease prediction

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The proteolytic activity in inflammatory bowel disease: insight from gut microbiota

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Stored white tea ameliorates DSS-induced ulcerative colitis in mice by modulating the composition of the gut microbiota and intestinal metabolites

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IL-22-dependent responses and their role during Citrobacter rodentium infection

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Bacteroides salyersiae Is a Candidate Probiotic Species with Potential Anti-Colitis Properties in the Human Colon: First Evidence from an In Vivo Mouse Model

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Integrating the serum proteomic and fecal metaproteomic to analyze the impacts of overweight/obesity on IBD: a pilot investigation

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Recruitment and Residence of Intestinal T Cells – Lessons for Therapy in Inflammatory Bowel Disease

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Gut Microbiota Mediates Skin Ulceration Syndrome Outbreak by Readjusting Lipid Metabolism in Apostichopus japonicus

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Advances in natural compound-based nanomedicine and the interaction with gut microbiota in ulcerative colitis therapy

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Integration and implementation of precision medicine in the multifaceted inflammatory bowel disease

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Anemoside B4 attenuates necrotic enteritis of laying hens induced by Clostridium perfringens via inhibiting NF-κB and PI3K/Akt/mTOR signalling pathways

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Restoring mucosal barrier homeostasis by in situ formation of a living-synthetic therapeutic coating

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Alfalfa Polysaccharide Alleviates Colitis by Regulating Intestinal Microbiota and the Intestinal Barrier Against the TLR4/MyD88/NF-κB Pathway

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A triple-helix white tea polysaccharide alleviates ulcerative colitis via the gut microbiota–metabolites–inflammation regulatory axis

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Food-derived extracellular vesicles: an emerging intervention strategy for inflammatory bowel disease

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Impact of dietary carbohydrate, fat or protein restriction on the human gut microbiome: a systematic review

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Aging Gut Microbiome in Healthy and Unhealthy Aging

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Core microbiome-associated proteins associated with ulcerative colitis interact with cytokines for synergistic or antagonistic effects on gut bacteria

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Dietary fiber for the prevention of childhood obesity: a focus on the involvement of the gut microbiota

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Regulation of Bacteroides acidifaciens by the aryl hydrocarbon receptor in IL-22-producing immune cells has sex-dependent consequential impact on colitis

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Peonidin-3-O-(3,6-O-dimalonyl-β-D-glucoside), a polyacylated anthocyanin isolated from the black corncobs, alleviates colitis by modulating gut microbiota in DSS-induced mice

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Novel histological repertoire of crypt-associated anomalies in inflamed colon mucosa

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Oleanolic acid 28-O-β-D-glucopyranoside: A novel therapeutic agent against ulcerative colitis via anti-inflammatory, barrier-preservation, and gut microbiota-modulation

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Do high-protein diets have the potential to reduce gut barrier function in a sex-dependent manner?

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Multi-omics reveals the alleviating effect of berberine on ulcerative colitis through modulating the gut microbiome and bile acid metabolism in the gut-liver axis

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Faecal proteomics links neutrophil degranulation with mortality in patients with alcohol-associated hepatitis

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Safety and efficacy of curcumin in the treatment of ulcerative colitis: An updated systematic review and meta-analysis of randomized controlled trials

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Mass spectrometry-based metabolomics approaches to interrogate host–microbiome interactions in mammalian systems

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An acidic polysaccharide from Lycium barbarum L: Isolation, purification, structural characterization, and therapeutic effects on ulcerative colitis

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Comprehensive metagenomic and lipidomic analysis showed that baicalin could improve depressive behaviour in atherosclerotic mice by inhibiting nerve cell ferroptosis

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A small‐molecule microtubule‐stabilizing agent safely reduces Aβ plaque and tau pathology in transgenic mouse models of Alzheimer's disease

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Organoids in gastrointestinal diseases: from bench to clinic

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Gut-Derived Ursodeoxycholic Acid from Saponins of Quinoa Regulated Colitis via Inhibiting the TLR4/NF-κB Pathway

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Diet–pathobiont interplay in health and inflammatory bowel disease

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A review of suspension trapping digestion method in bottom‐up proteomics

Duong, V., Park, J., & Lee, H. (2022) · Journal of Separation Science · doi:10.1002/jssc.202200297 · Cited by 12

Extremely small and incredibly close: Gut microbes as modulators of inflammation and targets for therapeutic intervention

Piazzesi, A., & Putignani, L. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.958346 · Cited by 12

Gut microbial ethanol metabolism contributes to auto-brewery syndrome in an observational cohort

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Navigating multi-omic integration methods for human microbiome research

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A Lipopolysaccharide-Enriched Cow’s Milk Allergy Microbiome Promotes a TLR4-Dependent Proinflammatory Intestinal Immune Response

Campbell, E., Hesser, L. A., Canani, R. B., Carucci, L., Paparo, L., Patry, R. T., & Nagler‐Anderson, C. (2024) · The Journal of Immunology · doi:10.4049/jimmunol.2300518 · Cited by 11

Integrated Microbiome-Metabolomics Analysis Reveals the Potential Mechanism of Dandelion Root Polysaccharides to Ameliorate Ulcerative Colitis

Yan, S., & Dong, R. (2024) · Metabolites · doi:10.3390/metabo14070351 · Cited by 12

Sustained mucosal colonization and fecal metabolic dysfunction by Bacteroides associates with fecal microbial transplant failure in ulcerative colitis patients

Zhang, B., Magnaye, K. M., Stryker, E., Anderson, J. M., Porsche, C. E., Hertz, S., McCauley, K. E., Smith, B. J., Zydek, M., Pollard, K. S., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-62463-8 · Cited by 11

Huang Lian Jie Du decoction attenuated colitis via suppressing the macrophage Csf1r/Src pathway and modulating gut microbiota

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Structural Variations in Ulcerative Colitis–associated Escherichia coli Reduce Fructose Utilization and Aggravate Inflammation Under High-Fructose Diet

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Exploring the health benefits of gut microbiota metabolites on combating ulcerative colitis via network pharmacology, bioinformatics and molecular docking

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Potential Phytotherapy of DSS-Induced Colitis: Ameliorating Reactive Oxygen Species-Mediated Necroptosis and Gut Dysbiosis with a New Crataegus pinnatifida Bunge Variety—Daehong

Lee, K.-I., Jo, Y., Yuk, H. J., Kim, S., Kim, H., Kim, H. J., Hwang, S.-K., & Park, K.-S. (2024) · Antioxidants · doi:10.3390/antiox13030340 · Cited by 11

Depressive disorder prevention by DIET crosslink: Diet, intestinal microbiota, enzyme and traits of metabolism

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Seaweed-derived bioactives: Gut microbiota targeted interventions for immune function

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Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution

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Understanding crosstalk between the gut and liver microbiome: pathogenesis to therapeutic approaches in liver cancer

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Constituents of stable commensal microbiota imply diverse colonic epithelial cell reactivity in patients with ulcerative colitis

Inčiūraitė, R., Gedgaudas, R., Lukoševičius, R., Tilinde, D., Ramonaitė, R., Link, A., Kašėtienė, N., Malakauskas, M., Kiudelis, G., Jonaitis, L. V., et al. (2024) · Gut Pathogens · doi:10.1186/s13099-024-00612-0 · Cited by 10

Effects of gut microbiota-derived short-chain fatty acids on cognitive impairment: An in-silico study

Nguyen, H. D., Vu, G. H., & Kim, W. (2024) · Aspects of Molecular Medicine · doi:10.1016/j.amolm.2024.100047 · Cited by 9

Predicting acute lung injury in infants with congenital heart disease after cardiopulmonary bypass by gut microbiota

Jiang, L., Cun, Y., Wang, Q., Wu, K., Hu, M., Wu, Z., Zhu, T., Yang, Z., Patel, N., Cai, X., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1362040 · Cited by 9

The Alleviating Effect of Abalone Viscera Collagen Peptide in DSS-Induced Colitis Mice: Effect on Inflammatory Cytokines, Oxidative Stress, and Gut Microbiota

Liu, B., Liu, L., Li, C., Guo, T., Li, C., Tian, M., & Fang, T. (2025) · Nutrients · doi:10.3390/nu17111926 · Cited by 9

Gut microbiota-derived Proline-Leucine dipeptide aggravated sepsis-induced acute lung injury via activating Nod2/NF-κB signaling pathway

Yang, L., He, S., Wei, A., Wang, X., He, L., Cui, L., Zhang, S., Zhong, C., Zhuo, Y., & Wang, X. (2025) · Molecular Immunology · doi:10.1016/j.molimm.2025.05.024 · Cited by 9

The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy

Zhang, L., Hu, L., Tan, L., Zhang, Z., Chen, M., Gan, W., Chen, L., Zou, Y., Wang, S., Pang, Y., et al. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1618947 · Cited by 9

Contributions of Synthetic Chemicals to Autoimmune Disease Development and Occurrence

Kosarek, N. N., & Preston, E. V. (2024) · Current Environmental Health Reports · doi:10.1007/s40572-024-00444-9 · Cited by 9

Structural elucidation of a capsular polysaccharide from Bacteroides uniformis and its ameliorative impact on DSS-induced colitis in mice

Ma, C., Zhang, S., Renaud, S. J., Zhang, Q., Qi, H., Zhou, H.-Y., Jin, Y., Yu, H., Xu, Y., Huang, H., et al. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.135119 · Cited by 9

Bile-Liver phenotype: Exploring the microbiota landscape in bile and intratumor of cholangiocarcinoma

Wang, L., Zhao, H. Y., Wu, F., Chen, J., Xu, H., Gong, W., Wen, S., Yang, M., Xia, J., Chen, Y., et al. (2025) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2025.03.030 · Cited by 8

Gut microbiome alterations and hepatic encephalopathy post-TIPS in liver cirrhosis patients

Li, S., Xu, Z., Diao, H., Zhou, A., Tu, D., Wang, S., Feng, Y., Feng, X., Lai, Y., Yang, S., et al. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06774-y · Cited by 8

Dual-mechanism mucoadhesive hydrogel integrating pH-independent barriers and autophagy-driven immunotherapy for the treatment of ulcerative colitis

Wang, J., Ouyang, S., Lin, G., Li, D., Ding, B., Chen, Y., Tong, B., Ouyang, T., Xu, H., & Wu, W. (2025) · Acta Biomaterialia · doi:10.1016/j.actbio.2025.09.006 · Cited by 8

Proteases in intestinal health and disease

Deraison, C., & Vergnolle, N. (2025) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-025-01129-w · Cited by 9

Alpha-lipoic acid improves intestinal homeostasis and ameliorates colitis through modulation of gut microbiota and production of short chain fatty acids in mice

Huang, S., Ding, H., Su, Y., Chen, Z., He, W., Chen, Z., & Zhu, H. (2026) · Food Research International · doi:10.1016/j.foodres.2026.118582 · Cited by 8

Dietary methionine restriction ameliorates ulcerative colitis in mice: A role for the H₂S and short-chain fatty acids balance via gut microbiota remodeling

Yang, H., Yang, Y., Qian, J., Hu, W., Jinjie, L. I. U., Mwabulili, F., Li, P., & Xie, Y. (2026) · Food Research International · doi:10.1016/j.foodres.2026.119038 · Cited by 8

Discovery of anthraquinones as DPP-IV inhibitors: Structure-activity relationships and inhibitory mechanism

Ma, H., Zhang, J., Li, C.-Q., & Zou, L. (2023) · Fitoterapia · doi:10.1016/j.fitote.2023.105549 · Cited by 8

Anaerobes in specific infectious and noninfectious diseases: new developments

Boyanova, L., Markovska, R. D., Yordanov, D., Gergova, R. T., & Hadzhiyski, P. (2023) · Anaerobe · doi:10.1016/j.anaerobe.2023.102714 · Cited by 8

Oral Administration of Bioactive Nanoparticulates for Inflammatory Bowel Disease Therapy by Mitigating Oxidative Stress and Restoring Intestinal Microbiota Homeostasis

Wu, H., Shi, C., Li, Q., Wang, L., Wang, R., Chen, F., Li, R., Guo, X., Chen, Y., & She, J. (2024) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.4c00499 · Cited by 7

Proteus mirabilis exacerbates ulcerative colitis by inhibiting mucin production

Jiang, Z., Li, P., Qiu, K., Liao, Y., Chen, X., Xuan, J., Wang, F., Ma, H., Wang, Y., & Zhu, M. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1556953 · Cited by 8

Unveiling the fungal frontier: mycological insights into inflammatory bowel disease

Chen, S., Yi, M., Yi, X., Zhou, Y., Song, H., & Zeng, M. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1551289 · Cited by 10

Dietary impact on the gut resistome: western diet independently increases the prevalence of antibiotic resistance genes within the gut microbiota

Keskey, R. C., Bluiminck, S., Sangwan, N., Meltzer, R. S., Lam, A., Thewissen, R., Zaborin, A., van Goor, H., Zaborina, O. Y., & Alverdy, J. C. (2025) · Microbiology Spectrum · doi:10.1128/spectrum.02766-24 · Cited by 7

Fucoidan-based hydrogel with ultrafast self-healing properties for enhanced probiotic delivery to alleviate colitis and microbiota dysbiosis in mice

Liu, Q., Yang, X., Zhong, X., Liu, W., Zhang, J., Xiang, S., & Tan, M. (2026) · Biomaterials · doi:10.1016/j.biomaterials.2026.123984 · Cited by 7

Novel insights into diarrhea mechanism from gut-kidney axis perspective: correlations among intestinal mucosal injury, AQP4 water transport disorder and gut microbiota dysbiosis

Peng, H., Peng, X., Liu, Q., Deng, N., Xie, X., & Tan, Z. (2026) · 3 Biotech · doi:10.1007/s13205-026-04774-3 · Cited by 7

Bifidobacterium breve modulates lactic acid to curtail Escherichia coli expansion and alleviate inflammatory bowel disease

Gao, X., Xia, Y., Sun, X., Dou, W., Chen, R., Huang, P., Yu, L., Tian, F., Zhao, J., Chen, W., et al. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.104626 · Cited by 7

Bowel preparation before colonoscopy: Consequences, mechanisms, and treatment of intestinal dysbiosis

Zheng, Z.-L., Zheng, Q.-F., Wang, L., & Liu, Y. (2024) · World Journal of Gastroenterology · doi:10.3748/wjg.v31.i2.100589 · Cited by 9

The colonic mucosal virome in inflammatory bowel disease reveals Crassvirales depletion and disease-specific virome features

Yan, A., Butcher, J., Mack, D. R., & Stintzi, A. P. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2539450 · Cited by 6

Gut commensal microbiota drive tailored macrophage responses

Jones, J. P., García-Martínez, K. Y., Lee, Y.-Y., Rhee, M. W., Nath, R. R., Takahashi, S., Grodner, B., Vlaminck, I. D., Leifer, C. A., & Brito, I. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116157 · Cited by 7

OP31 Meta–omics reveals microbiome-driven proteolysis as a contributing factor to the severity of ulcerative colitis disease activity

Mills, R. H., Dulai, P. S., Vázquez‐Baeza, Y., Zhu, Q., Humphrey, G., Goldasich, L. D., Quinn, R. A., Gewirtz, A. T., Chassaing, B., Chu, H., et al. (2020) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjz203.030 · Cited by 2

A35 MICROBIAL PROTEOLYTIC SIGNATURE IN ULCERATIVE COLITIS INDUCES AN INFLAMMATORY SIGNATURE IN MICROBIOTA-HUMANIZED MICE

Galipeau, H. J., Turpin, W., Fernández, A. C., Santiago, A., Libertucci, J., Bermúdez-Brito, M., Armstrong, S., Bedrani, L., Croitoru, K., & Verdu, E. F. (2020) · Journal of the Canadian Association of Gastroenterology · doi:10.1093/jcag/gwz047.034

Novel Fecal Biomarkers That Precede Clinical Diagnosis of Ulcerative Colitis

Galipeau, H. J., Caminero, A., Turpin, W., Bermudez-Brito, M., Santiago, A., Libertucci, J., Constante, M., Raygoza Garay, J. A., Rueda, G., Armstrong, S., et al. (2021) · Gastroenterology · doi:10.1053/j.gastro.2020.12.004 · Cited by 190

Proteolytic Colonic Microbiota Is Associated with Increased Clinical and Endoscopic Disease Activity in Ulcerative Colitis Running head : Microbiota and disease activity in ulcerative colitis

Kwenandar, J., Parewangi, A. M. L., Syahriani, F., Bakri, S., Bayu, D., & Seweng, A. (2026) · International Journal of Drug Delivery Technology · doi:10.25258/ijddt.16.57s.9

A276 CHARACTERIZING MICROBIOTA COMPOSITION AND FUNCTION THAT PRECEDE DEVELOPMENT OF CLINICALLY RELEVANT INFLAMMATION IN UC PATIENTS

Bermúdez-Brito, M., Galipeau, H. J., Fernández, A. C., Turpin, W., Bedrani, L., Croitoru, K., & Verdu, E. F. (2018) · Journal of the Canadian Association of Gastroenterology · doi:10.1093/jcag/gwy009.276