The DOI matches its Crossref record; 260 of the 260 references it cites were found in a registry or an index.
Global epidemiology, health burden and effective interventions for elevated blood pressure and hypertension
Open accessAbstract
High blood pressure is one of the most important risk factors for ischaemic heart disease, stroke, other cardiovascular diseases, chronic kidney disease and dementia. Mean blood pressure and the prevalence of raised blood pressure have declined substantially in high-income regions since at least the 1970s. By contrast, blood pressure has risen in East, South and Southeast Asia, Oceania and sub-Saharan Africa. Given these trends, the prevalence of hypertension is now higher in low-income and middle-income countries than in high-income countries. In 2015, an estimated 8.5 million deaths were attributable to systolic blood pressure >115 mmHg, 88% of which were in low-income and middle-income countries. Measures such as increasing the availability and affordability of fresh fruits and vegetables, lowering the sodium content of packaged and prepared food and staples such as bread, and improving the availability of dietary salt substitutes can help lower blood pressure in the entire population. The use and effectiveness of hypertension treatment vary substantially across countries. Factors influencing this variation include a country's financial resources, the extent of health insurance and health facilities, how frequently people interact with physicians and non-physician health personnel, whether a clear and widely adopted clinical guideline exists and the availability of medicines. Scaling up treatment coverage and improving its community effectiveness can substantially reduce the health burden of hypertension.
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Cites
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Self-citation2018 ESC/ESH Guidelines for the management of arterial hypertension
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Cited by
Zhou, B., Carrillo-Larco, R. M., Danaei, G., Riley, L. M., Paciorek, C. J., Stevens, G. A., Gregg, E. W., Bennett, J. E., Solomon, B., Singleton, R. K., et al. (2021) · The Lancet · doi:10.1016/s0140-6736(21)01330-1 · Cited by 3,902
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Mostert, C. M., Udeh-Momoh, C., Winkler, A. S., McLaughlin, C., Eyre, H., Salama, M., Ranchod, K., Trepel, D., Vradenburg, G., Hynes, W., et al. (2025) · eBioMedicine · doi:10.1016/j.ebiom.2025.105950 · Cited by 42
Challenges of managing hypertension in Pakistan - a review
Elahi, A., Ali, A. A., Khan, A. H., Samad, Z., Shahab, H., Aziz, N., & Almas, A. (2023) · Clinical Hypertension · doi:10.1186/s40885-023-00245-6 · Cited by 34
Latest hypertension research to inform clinical practice in Asia
Kario, K., Mogi, M., & Hoshide, S. (2022) · Hypertension Research · doi:10.1038/s41440-022-00874-8 · Cited by 32
Metadata
- Authors
- Zhou, B., Perel, P., Mensah, G. A., & Ezzati, M.
- Venue
- Nature Reviews Cardiology
- Published
- 2021-05-28
- Volume
- 18
- Issue
- 11
- Pages
- 785-802
- ISSN
- 1759-5002 (ISSN-L)
- 1759-5010
- OpenAlex
- W3164570271
- Cited by
- 1,521
- References
- 260
- FWCI
- 56.99
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Zhou, B., Perel, P., Mensah, G. A., & Ezzati, M. (2021). Global epidemiology, health burden and effective interventions for elevated blood pressure and hypertension. Nature Reviews Cardiology. https://doi.org/10.1038/s41569-021-00559-8
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
