Cited by 32Blood Pressure and Hypertension StudiesSodium Intake and HealthClinical practice guidelines implementation

Latest hypertension research to inform clinical practice in Asia

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Kario, Kazuomi, Mogi, Masaki, Hoshide, Satoshi·2022·Hypertension Research

Abstract

Despite the challenges associated with the coronavirus pandemic, the last 2 years have been active periods for hypertension research and initiatives in Asia. There are new hypertension guidelines from the World Health Organization that can be interpreted and applied locally. This is also the case for data from the latest Blood Pressure Lowering Treatment Trialists' Collaboration meta-analysis, which showed that greater reductions in systolic blood pressure (BP) are associated with lower risks of cardiovascular events. The randomized controlled Strategy of Blood Pressure Intervention in the Elderly Hypertensive study and the Salt Substitute and Stroke Study provide local data to inform practice. Other initiatives to help reduce high salt intake in Asia are also underway. Both drug-resistant and nocturnal hypertension are appropriate areas of focus in Asia, and there are an increasing number of pharmacological and non-pharmacological treatment options for these conditions. Digital therapeutics to promote uptake and implementation of lifestyle interventions are showing promise, and other digital-based strategies such as telemedicine, wearable BP monitors to detect beat-by-beat BP and artificial intelligence will no doubt become integral parts of future strategies to reduce the burden of hypertension and hypertension-related disease. A number of initiatives from the Hypertension Cardiovascular Outcome Prevention and Evidence in Asia Network and Japanese Society of hypertension are underway, and there is good reason for optimism regarding the ongoing and future management of hypertension in Asia based on these and the active research activities in the region.

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  • Asians generally experience greater benefits from strict blood pressure control compared to Western populations.

    “It's important to highlight that Asians generally seems to experience greater benefits (reduced the onset of cardiovascular disease, stroke, coronary artery disease and heart failure) from strict BP control compared to Western populations (Fig. 1) [3].”

    From The WHO Global report 2023 on hypertension warning the emerging hypertension burden in globe and its treatment strategy (2024) · cites this paper as [3]

    The STEP study section reports greater cardiovascular risk reduction with intensive blood-pressure lowering in older Chinese patients than in the Western comparator studies. It says this may indicate greater benefits in elderly Asian populations, but calls for further study; it does not establish the claim for Asians generally. (LLM, conf=0.88)

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Research works printed but not linked: 2

  1. [3]3. Lippi G, Wong J, Henry BM. Hypertension in patients with coronavirus disease 2019 (COVID-19): a pooled analysis. Pol Arch Intern Med. 2020;130:304-9.
  2. [145]145. Kario K, Kanegae H, Tomitani N, Okawara Y, Fujiwara T, Yano Y, et al. Nighttime blood pressure measured by home blood pressure monitoring as an independent predictor of cardiovas- cular events in general practice. Hypertension. 2019;73:1240-8.

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Authors
Kario, K., Mogi, M., & Hoshide, S.
Affiliations
  • Jichi Medical University (JP)
  • Ehime University (JP)
Corresponding author
Kario, Kazuomi
Venue
Hypertension Research
Published
2022-04
Volume
45
Issue
4
Pages
555-572
ISSN
  • 0916-9636 (ISSN-L)
  • 1348-4214
OpenAlex
W4223416607
Cited by
32
References
173
Citations by year
2026: 5 · 2025: 4 · 2024: 11 · 2023: 3 · 2022: 9
FWCI
4.74
Type
journal article
Language
en
Open access
Locations
  • Hypertension Research (publishedVersion)
  • PubMed (publishedVersion)
Funders
Jichi Medical University
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
  • Health Sciences › Nursing › Nutrition and Dietetics › Sodium Intake and Health
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
Keywords
hypertension, hypertension guidelines, WHO guidelines, blood pressure reduction, cardiovascular events, systolic blood pressure reduction, salt reduction, resistant hypertension, nocturnal hypertension, digital therapeutics, telemedicine, wearable blood pressure monitor, artificial intelligence, lifestyle intervention
MeSH terms
Aged, Artificial Intelligence, Asia, Blood Pressure, Humans, Hypertension, Blood Pressure Monitoring, Ambulatory

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