The DOI matches its Crossref record; 159 of the 161 references it cites were found in a registry or an index.
Epicardial adipose tissue in contemporary cardiology
Open accessAbstract
Interest in epicardial adipose tissue (EAT) is growing rapidly, and research in this area appeals to a broad, multidisciplinary audience. EAT is unique in its anatomy and unobstructed proximity to the heart and has a transcriptome and secretome very different from that of other fat depots. EAT has physiological and pathological properties that vary depending on its location. It can be highly protective for the adjacent myocardium through dynamic brown fat-like thermogenic function and harmful via paracrine or vasocrine secretion of pro-inflammatory and profibrotic cytokines. EAT is a modifiable risk factor that can be assessed with traditional and novel imaging techniques. Coronary and left atrial EAT are involved in the pathogenesis of coronary artery disease and atrial fibrillation, respectively, and it also contributes to the development and progression of heart failure. In addition, EAT might have a role in coronavirus disease 2019 (COVID-19)-related cardiac syndrome. EAT is a reliable potential therapeutic target for drugs with cardiovascular benefits such as glucagon-like peptide 1 receptor agonists and sodium-glucose co-transporter 2 inhibitors. This Review provides a comprehensive and up-to-date overview of the role of EAT in cardiovascular disease and highlights the translational nature of EAT research and its applications in contemporary cardiology.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Perivascular and epicardial adipose tissue impose direct adverse effects on the vascular endothelium and myocardium. 30”
From Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (2023) · cites this paper as [30]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Visceral adiposity in particular has been causally implicated in adverse cardiovascular outcomes via the release of proinflammatory cytokines.6”
From Semaglutide and cardiovascular outcomes by baseline and changes in adiposity measurements: a prespecified analysis of the SELECT trial (2025) · cites this paper as [6]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Paracardiac adipose tissue has been hypothesized to act in a paracrine manner, with release of proinflammatory and profibrotic adipocytokines and excess free fatty acids with resultant intramyocardial lipid accumulation and myocardial inflammation and fibrosis.19”
From Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure (2025) · cites this paper as [19]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
Zinman, B., Wanner, C., Lachin, J. M., Fitchett, D., Bluhmki, E., Hantel, S., Mattheus, M., Devins, T., Johansen, O. E., Woerle, H. J., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1504720 · Cited by 12,315
Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes
Marso, S. P., Daniels, G. H., Brown-Frandsen, K., Kristensen, P., Mann, J. F. E., Nauck, M. A., Nissen, S. E., Pocock, S., Poulter, N. R., Ravn, L. S., et al. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1603827 · Cited by 7,629
Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes
Marso, S. P., Bain, S. C., Consoli, A., Eliaschewitz, F. G., Jódar, E., Leiter, L. A., Lingvay, I., Rosenstock, J., Seufert, J., Warren, M. L., et al. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1607141 · Cited by 6,900
Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes
Wiviott, S. D., Raz, I., Bonaca, M. P., Mosenzon, O., Kato, E. T., Cahn, A., Silverman, M. G., Zelniker, T. A., Kuder, J. F., Murphy, S. A., et al. (2019) · New England Journal of Medicine · doi:10.1056/nejmoa1812389 · Cited by 6,382
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
Lan, J., Ge, J., Yu, J., Shan, S., Zhou, H., Fan, S., Zhang, Q., Shi, X., Wang, Q., Zhang, L., et al. (2020) · Nature · doi:10.1038/s41586-020-2180-5 · Cited by 5,983
2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure
Yancy, C. W., Jessup, M. L., Bozkurt, B., Butler, J., Casey, D. E., Colvin, M. M., Drazner, M. H., Filippatos, G. S., Fonarow, G. C., Givertz, M. M., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.04.025 · Cited by 3,532
Gerstein, H. C., Colhoun, H. M., Dagenais, G. R., Diaz, R., Lakshmanan, M., Pais, P., Probstfield, J., Riesmeyer, J. S., Riddle, M. C., Rydén, L., et al. (2019) · The Lancet · doi:10.1016/s0140-6736(19)31149-3 · Cited by 3,163
Yancy, C. W., Jessup, M., Bozkurt, B., Butler, J., Casey, D. E., Colvin, M. M., Drazner, M. H., Filippatos, G. S., Fonarow, G. C., Givertz, M. M., et al. (2017) · Circulation · doi:10.1161/cir.0000000000000509 · Cited by 3,109
COVID-19 and the cardiovascular system
Zheng, Y.-Y., Ma, Y.-T., Zhang, J.-Y., & Xie, X. (2020) · Nature Reviews Cardiology · doi:10.1038/s41569-020-0360-5 · Cited by 2,970
Myocardial Fatty Acid Metabolism in Health and Disease
Lopaschuk, G. D., Ussher, J. R., Folmes, C. D. L., Jaswal, J. S., & Stanley, W. C. (2010) · Physiological Reviews · doi:10.1152/physrev.00015.2009 · Cited by 2,228
Cited by
Sorted by citations
Items 201–300 of 812
Анатольевна, К. О., Naryzhnaya, N. V., Кологривова, И. В., Суслова, Т. Е., Kravchenko, E. S., Анатольевна, Х. О., Andreev, S. L., Margolis, N. Y., Sharipova, N. G., & Сергеевна, К. А. (2023) · Сибирский журнал клинической и экспериментальной медицины · doi:10.29001/2073-8552-2023-38-1-64-74 · Cited by 10
Ruocco, C., Malavazos, A. E., Ragni, M., Carruba, M. O., Valerio, A., Iacobellis, G., & Nisoli, E. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.106892 · Cited by 10
Self-citationLin, T., Lee, C., Huang, K., Wu, C., Lee, J., Lan, C.-W., Su, M.-Y. M., Hwang, J., Wang, Y., & Lin, L. (2023) · Journal of the American Heart Association · doi:10.1161/jaha.122.027781 · Cited by 10
Wang, Z., Li, J., Chen, J., Guo, H., He, H., Jiao, S., Chen, Y., Dong, J., & Sun, Y.-H. (2023) · Circulation Journal · doi:10.1253/circj.cj-23-0474 · Cited by 9
Wang, Y., Wang, A., Wang, L., Tan, W., Xu, L., Wang, J., Li, S., Liu, J., Sun, Y., Yang, B., et al. (2024) · Biomedical Signal Processing and Control · doi:10.1016/j.bspc.2024.107167 · Cited by 9
Marcon, L. M. R., & Mazzieri, A. (2025) · Immuno · doi:10.3390/immuno5010011 · Cited by 11
Methods to model epicardial adipose tissue-mediated atrial fibrillation
Cook, L., Perry, M., Hill, A. P., & Thorpe, J. (2025) · npj Cardiovascular Health · doi:10.1038/s44325-025-00065-7 · Cited by 9
Epicardial adipose tissue and new-onset atrial fibrillation in a Danish cohort
Pedersen, J. J., Kühl, J. T., Elming, M. B., Pham, M. H. C., Sigvardsen, P. E., Nordestgaard, B. G., Fuchs, A., Køber, L., & Kofoed, K. F. (2025) · European Heart Journal · doi:10.1093/eurheartj/ehaf515 · Cited by 9
Crum, Y., van Veldhuisen, D. J., Shah, S. J., Mylavarapu, U., Hu, M., Komtebedde, J., Lobeek, M., Hoendermis, E. S., Litwin, S. E., Solomon, S. D., et al. (2025) · JACC Advances · doi:10.1016/j.jacadv.2025.102185 · Cited by 9
He, S., Zhu, H., Zhang, J., Yang, X., & Zhao, L. (2023) · PubMed Central · Cited by 9
Dogan, N., Ozuynuk, A. S., Balkanay, O. O., Yıldız, C. E., Güçlü-Geyik, F., Kirsan, C. B., & Çoban, N. (2023) · Gene · doi:10.1016/j.gene.2023.147988 · Cited by 8
Kotha, S., Plein, S., Greenwood, J. P., & Levelt, E. (2024) · Therapeutic Advances in Endocrinology and Metabolism · doi:10.1177/20420188241229540 · Cited by 11
Cheang, I., Zhu, X., Yue, X., Tang, Y. Y., Gao, Y., Lu, X., Shi, S., Liao, S., Yao, W., Zhou, Y., et al. (2023) · iScience · doi:10.1016/j.isci.2023.106755 · Cited by 9
Epicardial adipose tissue in heart failure: risk factor or mediator?
Inciardi, R. M., & Chandra, A. (2022) · European Journal of Heart Failure · doi:10.1002/ejhf.2577 · Cited by 8
Cui, M., Bao, S., Li, J., Dong, H., Xu, Z., Yan, F., & Yang, W. (2024) · The International Journal of Cardiovascular Imaging · doi:10.1007/s10554-024-03096-w · Cited by 8
Obesity and Transcatheter Aortic Valve Replacement
Seo, J., Kharawala, A., Borkowski, P., Singh, N., Akunor, H., Nagraj, S., Avgerinos, D. V., & Kokkinidis, D. G. (2024) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd11060169 · Cited by 8
Marttila, J., Sipola, P., Juutilainen, A., Sillanmäki, S., Hedman, M., & Kuusisto, J. (2024) · High Blood Pressure & Cardiovascular Prevention · doi:10.1007/s40292-024-00659-9 · Cited by 8
Epicardial Adipose Tissue and Psoriasis: A Systematic Review and Meta-Analysis
Chen, X., Xiang, H., Lü, J., & Yang, M. J. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13164761 · Cited by 8
How Semaglutide Effects on Epicardial Fat Inflammation Can Be Good for the Heart
Iacobellis, G., & Malavazos, A. E. (2025) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2024.08.088 · Cited by 8
Self-citationPop, A. S. K., Dănilă, M. D., Giuchici, S., Buriman, D. G., Lolescu, B. M., Sturza, A., Muntean, D. M., & Lascu, A. (2025) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2024-0384 · Cited by 8
Zhu, R., Wang, W., Gao, Y., Wang, J., Li, B., Cheng, Z., Ji, C., Gu, H. C., Yuan, X., Yang, S., et al. (2025) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-025-01695-8 · Cited by 8
Alizadehasl, A., Mokhayeri, M., Sohani, Z., Zamanian, M. Y., Shahbazi, P., & Borzouei, S. (2025) · Clinical Cardiology · doi:10.1002/clc.70153 · Cited by 10
Yamaura, H., Otsuka, K., Ishikawa, H., Hojo, K., Matsumoto, K., Fujisawa, N., Okamoto, A., Yamaguchi, T., Kagawa, S., Shimada, T., et al. (2025) · European Heart Journal - Imaging Methods and Practice · doi:10.1093/ehjimp/qyaf079 · Cited by 8
Peri-Atrial Adipose Tissue Inflammation in Atrial Fibrillation
Vickneson, K., Gharaviri, A., Vigneswaran, V., Tonko, J., Bodagh, N., Kliś, M., Kotadia, I., Wright, M. J., Newby, D. E., Dweck, M. R., et al. (2025) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2025.04.023 · Cited by 8
Sarcopenia and sarcopenic obesity in cardiovascular disease: a comprehensive review
Tan, L. F., Sia, C., & Merchant, R. A. (2025) · Singapore Medical Journal · doi:10.4103/singaporemedj.smj-2024-233 · Cited by 10
Gerculy, R., Benedek, I., Kovács, I., Raț, N., Rodean, I. P., Matyas, B., Blîndu, E., Păcurar, D., Grigoroaea, C.-G., & Benedek, T. (2025) · Diagnostics · doi:10.3390/diagnostics15162003 · Cited by 8
From Cushion to Culprit: The Role of Epicardial Adipose Tissue in Cardiovascular Disease
Khanna, S., Mann, G. V., Vasanthakumar, S. A., Arnott, C. G., & Nerlekar, N. (2025) · Heart Lung and Circulation · doi:10.1016/j.hlc.2025.07.010 · Cited by 11
Zhou, Y., Yan, H., Zhu, Y., Jiang, W., & Zhang, S. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1701459 · Cited by 8
Oxidative Stress in Diabetic Cardiomyopathy: Molecular Mechanisms and Emerging Therapeutic Targets
Capece, U., Nilo, D., Morciano, C., Nilo, R., Spiezia, S., Sircana, M. C., Russo, V., Perrone, M. A., Bonfrate, L., Acierno, C., et al. (2026) · Biomolecules · doi:10.3390/biom16030470 · Cited by 11
Das, S. S., Kar, A., Rajkumar, S., Lee, S. H., Alvarez, M., Pietiläinen, K. H., & Pajukanta, P. (2023) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.123.319358 · Cited by 8
Quarta, S., Santarpino, G., Carluccio, M. A., Calabriso, N., Maffia, M., Siculella, L., Damiano, F., Madonna, R., & Massaro, M. (2023) · Vascular Pharmacology · doi:10.1016/j.vph.2023.107210 · Cited by 10
Macías-Cervantes, H. E., Martínez-Ramírez, D. B., Hinojosa-Gutiérrez, L. R., Córdova-Silva, D. A., & Rios-Muñoz, J. A. (2023) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2023.102213 · Cited by 8
Progenitor Cell Function and Cardiovascular Remodelling Induced by SGLT2 Inhibitors
Stougiannou, T. M., Christodoulou, K. C., Koufakis, T., Mitropoulos, F. A., Mikroulis, D. A., Mazer, C. D., & Karangelis, D. (2024) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2904145 · Cited by 9
Ballatore, A., Gatti, M., Mella, S., Tore, D., Xhakupi, H., Giorgino, F., Saglietto, A., Carmagnola, L., Roagna, E., Ferrari, G. M. D., et al. (2024) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd11050137 · Cited by 8
Evaluation of epicardial adipose tissue in children with type 1 diabetes
Trabzon, G., Güngör, Ş., Güllü, Ş. D., Çalışkan, O. F., & Güllü, U. U. (2024) · Pediatric Research · doi:10.1038/s41390-024-03319-9 · Cited by 8
Ryk, A., Marcinkiewicz, A. M., Chrzanowski, J., Michalak, A., Dróźdż, I., Burzyński, J., Krejca, M., & Fendler, W. M. (2024) · Cardiovascular Diabetology · doi:10.1186/s12933-024-02322-y · Cited by 8
Camatti, J., Santunione, A. L., Draisci, S., Antonella, D., Amorico, M. G., Ligabue, G., Silingardi, E., Torricelli, P., & Cecchi, R. (2024) · Forensic Imaging · doi:10.1016/j.fri.2024.200620 · Cited by 8
Role of Epicardial Adipose Tissue in Triggering and Maintaining Atrial Fibrillation
Wang, W., Tian, Y., Wang, W., Yin, H., Yin, D., & Tian, Y. (2022) · Cardiovascular Innovations and Applications · doi:10.15212/cvia.2022.0012 · Cited by 8
Aburel, O.-M., Brăescu, L., Buriman, D. G., Merce, A. P., Bînă, A. M., Borza, C., Mornoş, C., Sturza, A., & Muntean, D. M. (2024) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-024-05092-z · Cited by 7
Evans, A. J., & Li, Y. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252212464 · Cited by 8
Long-term effects of SGLT2 inhibitors on arrhythmias: a systematic review and meta-analysis
Li, P., Chen, W., Chen, R., Zhang, H., Yu, Z., Yan, H., Du, B., & Yang, P. C. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1558367 · Cited by 8
Yu, J., Zhang, Y., Zhang, T., Bi, Y., Chen, Y., Chen, Z. L., Dai, Z., Guo, F., Guo, L., Hu, C., et al. (2025) · Life Medicine · doi:10.1093/lifemedi/lnaf027 · Cited by 8
Firouznia, M., Molnar, D., Edin, C., Hjelmgren, O., Östgren, C. J., Lundberg, P., Henningsson, M., Bergström, G. M. L., & Carlhäll, C. (2025) · Radiology Cardiothoracic Imaging · doi:10.1148/ryct.240531 · Cited by 7
Watanabe, R., Yokoyama, K., Nagashima, K., Hirata, M., Hirata, S., Wakamatsu, Y., Sawada, M., Kurokawa, S., Ikeda, A., Murotani, K., et al. (2025) · Journal of the American Heart Association · doi:10.1161/jaha.125.043484 · Cited by 7
Bresticker, J. E., Pavelec, C. M., Echols, J. T., Patel, A. R., Wolf, M. J., & Epstein, F. H. (2025) · Journal of Cardiovascular Magnetic Resonance · doi:10.1016/j.jocmr.2025.101947 · Cited by 7
Song, Y., Hu, M., Ren, H., Fang, Q., Zheng, T., Feng, Z., Wang, X., Xu, L., & Gong, L. (2025) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jeaf305 · Cited by 7
de Vecchi, A., Cámara, Ó., Cavarra, R., del Álamo, J. C., El‐Bouri, W. K., Ferro, A., Lu, H. H.-S., Melidoro, P., Ogbomo-Harmitt, S., Olier, I., et al. (2026) · Thrombosis and Haemostasis · doi:10.1055/a-2761-5903 · Cited by 7
Epicardial Adipose Tissue, Coronary Plaque Progression, and Major Adverse Cardiovascular Events
Filtz, A., Lorenzatti, D., Scotti, A., Bhatia, K., Yametti, F. C., Cossettini, F. J., Chang, H., Lee, S. W., Slomka, P. J., Berman, D. S., et al. (2026) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2026.02.003 · Cited by 7
Requena-Ibáñez, J. A., Santos‐Gallego, C. G., & Badimón, J. J. (2022) · Revista Española de Cardiología (English Edition) · doi:10.1016/j.rec.2022.04.019 · Cited by 7
Dye, C. A., Cruz, M. D., Larsen, T. R., Nair, G. G., Marinescu, K. K., Suboc, T. M. B., Engelstein, E. D., Marsidi, J. L., Patel, P., Sharma, P. S., et al. (2023) · American Heart Journal Plus Cardiology Research and Practice · doi:10.1016/j.ahjo.2023.100309 · Cited by 7
Hu, Y., Jiang, S., Yu, X., Huang, S., Lan, Z., Yu, Y., Zhang, X., Chen, J., & Zhang, J. (2023) · Quantitative Imaging in Medicine and Surgery · doi:10.21037/qims-23-233 · Cited by 7
Yang, L., Yu, W., Wan, P., Wang, J., Shao, X., Zhang, F., Yang, X., Chen, Y., Li, Q., Jiang, D., et al. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1261215 · Cited by 7
Li, T.-L., Zhu, N.-N., Yin, Z., Sun, J., Guo, J.-P., Yuan, H., Shi, X., Guo, H., Li, S., & Shan, Z. (2024) · Gene · doi:10.1016/j.gene.2024.148528 · Cited by 7
Kitagawa, T., Sentani, K., Ikegami, Y., Takasaki, T., Takahashi, S., & Nakano, Y. (2024) · Circulation Journal · doi:10.1253/circj.cj-24-0226 · Cited by 8
Amangurbanova, M., Daher, R., Asbeutah, A. A., Vemuri, B., Mirza, H. M., Waseem, S., Malik, A., & Welty, F. K. (2024) · Journal of clinical lipidology · doi:10.1016/j.jacl.2024.06.006 · Cited by 7
McCarthy, B. E., Feng, R., Torigian, D. A., Tong, Y., Fritz, J. S., Minhas, J., Mazurek, J. A., Smith, K. A., Palevsky, H. I., Pugliese, S. C., et al. (2024) · CHEST Journal · doi:10.1016/j.chest.2024.11.020 · Cited by 7
Ritvo, P.-G., Charpentier, E., Zeitouni, M., Rahoual, G., Boussouar, S., Croisille, C., Silvain, J., Kernéis, M., Procopi, N., Rouanet, S., et al. (2025) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jeae335 · Cited by 7
Edsen, F., Habib, P., Matz, O., Nikoubashman, O., Wiesmann, M., Frick, M., Marx, N., Schulz, J. B., Reich, A., & Pinho, J. (2022) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.51617 · Cited by 7
Xuan, Y., Pang, S., Xie, W., He, R., Li, Q., & Yuan, J. (2023) · Medicine · doi:10.1097/md.0000000000035976 · Cited by 6
Zhan, W., Li, Y., Luo, H., He, J., Jiao, L., Xu, Y., & Yang, Y. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1462566 · Cited by 6
Clinical Role of Epicardial Adipose Tissue
Raggi, P., & Stillman, A. E. (2025) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2025.02.021 · Cited by 8
Peng, R., Meng, W., Lei, D., Shen, Q., Xu, Y., Changzheng, G., Qizhong, G., & Xiaoyan, W. (2025) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2025.06.003 · Cited by 6
Epicardial Fat Thickness as a Marker of Coronary Artery Disease in Diabetics: A Single Center Study
Akhter, A., Aisha, F., Moazzam, A. B., Khan, S. H. B., Malik, J., & Perveen, A. (2025) · Clinical Cardiology · doi:10.1002/clc.70171 · Cited by 6
Cinti, F., Morciano, C., Guarneri, A., Cappannoli, L., Sorice, G. P., Gugliandolo, S., Capece, U., Splendore, A., Avolio, A., Mezza, T., et al. (2025) · Cardiovascular Diabetology · doi:10.1186/s12933-025-02912-4 · Cited by 9
Quarta, S., SANTARPINO, G., Calabriso, N., Carluccio, M. A., Siracusa, L., Strano, T., Cardetta, F., Siculella, L., Damiano, F., Caterina, R. D., et al. (2026) · Food & Function · doi:10.1039/d5fo03219a · Cited by 6
Sowa, H., Karasaki, K., Ishiwata, M., Cheng, X., Hashimoto, M., & Ueda, K. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2026.1766197 · Cited by 7
Oikonomou, E. K., Chan, K., Patel, P., Wahome, E., Dangas, K., Desai, R., Sobirov, I., Khera, R., Petersen, S. E., Pugliese, F., et al. (2026) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2026.02.5116 · Cited by 6
Epicardial Adipose Tissue: A Piece of The Puzzle in Pediatric Hypertension
Schweighofer, N., Rupreht, M., Varda, N. M., Caf, P., Povalej, P., & Kanič, V. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12062192 · Cited by 10
Gavara, J., Merenciano-Gonzalez, H., Llopis‐Lorente, J., Molina-García, T., Pérez-Solé, N., de Dios, E., Marcos‐Garcés, V., Monmeneu, J. V., López-Lereu, M. P., Cànoves, J., et al. (2024) · Diagnostics · doi:10.3390/diagnostics14040368 · Cited by 6
Wang, X., Leng, S., Adamson, P. D., Greer, C., Huang, W., Lee, H. K., Loong, Y. T., Raffiee, N. A. S., Sia, C., Tan, S. Y., et al. (2025) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jeaf019 · Cited by 6
Lorenzatti, D., Filtz, A., Geers, J., Grodecki, K., Jaspan, V. N., Pierce, C., Miller, M. J., Park, C. M., Danilov, A., Blankstein, R., et al. (2025) · Journal of cardiovascular computed tomography · doi:10.1016/j.jcct.2025.01.008 · Cited by 6
Proarrhythmic Lipid Inflammatory Mediators: Mechanisms in Obesity Arrhythmias
Taqanaki, P. B., Aromolaran, K. A., & Aromolaran, A. S. (2025) · Journal of Cellular Physiology · doi:10.1002/jcp.70012 · Cited by 6
Gangitano, E., Barbaro, G., Gnessi, L., Iacobellis, G., & Lubrano, C. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06335-3 · Cited by 6
Self-citationKatsura, M., Horiuchi, Y., Yoshiura, D., Yahagi, K., Gonda, Y., Asami, M., Taniwaki, M., Komiyama, K., Yuzawa, H., Tanaka, J., et al. (2025) · Heart and Vessels · doi:10.1007/s00380-025-02576-w · Cited by 6
Benefits of GLP-1 Mimetics on Epicardial Adiposity
Yaribeygi, H., Maleki, M., Nasimi, F. S., Jamialahmadi, T., Stanford, F. C., & Sahebkar, A. (2023) · Current Medicinal Chemistry · doi:10.2174/0929867330666230113110431 · Cited by 6
Yang, Z., Tang, D., Luo, Y., Xiang, C., Huang, L., & Xia, L. (2023) · British Journal of Radiology · doi:10.1259/bjr.20221030 · Cited by 6
Han, W. M., Apornpong, T., Chattranukulchai, P., Siwamogsatham, S., Lwin, H. M. S., Boonrungsirisap, J., Wichiansan, T., Gatechompol, S., Ubolyam, S., Kerr, S. J., et al. (2023) · HIV Medicine · doi:10.1111/hiv.13499 · Cited by 6
Epicardial fat thickness in type 2 diabetes outpatient care
Iacobellis, G., Goldberger, J. J., Malavazos, A. E., Sterling, C. M., & Canturk, A. (2023) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2023.10.016 · Cited by 6
Self-citationFukuta, H., Goto, T., & Kamiya, T. (2024) · IJC Heart & Vasculature · doi:10.1016/j.ijcha.2024.101444 · Cited by 6
Extrarenal Benefits of SGLT2 Inhibitors in the Treatment of Cardiomyopathies
Yerra, V. G., & Connelly, K. A. (2024) · Physiology · doi:10.1152/physiol.00008.2024 · Cited by 6
Perivascular and epicardial adipose tissue
Badimón, L., Arderiu, G., Vilahur, G., Padró, T., Cordero, A., & Mendieta, G. (2023) · Vascular Pharmacology · doi:10.1016/j.vph.2023.107254 · Cited by 5
Piña, P., Lorenzatti, D., Filtz, A., Scotti, A., Gil, E. V., Torres, J. D., Perea, C. M., Shaw, L. J., Lavie, C. J., Berman, D. S., et al. (2025) · The International Journal of Cardiovascular Imaging · doi:10.1007/s10554-024-03307-4 · Cited by 6
Self-citationKhan, I., Hondros, C. A. B., Hanseth, S., Pedersen, E. R., Hovland, S., Larsen, T. H., & Lønnebakken, M. T. (2025) · Coronary Artery Disease · doi:10.1097/mca.0000000000001539 · Cited by 5
Yu, T., Wang, P., & Dong, Z. (2025) · International Journal of Obesity · doi:10.1038/s41366-025-01852-z · Cited by 7
Yu, L., Yang, W., Ling, R., Yu, Y., Dai, X. D., Sun, J., Zhang, J., & Zheng, X. (2025) · La radiologia medica · doi:10.1007/s11547-025-02063-2 · Cited by 5
Perivascular adipose tissue in cardiovascular disease: From mechanisms to therapeutic targets
Ueda, K. (2025) · Journal of Cardiology · doi:10.1016/j.jjcc.2025.08.001 · Cited by 5
Peripulmonary Vein Adipose Tissue Attenuation as a Novel Marker of Atrial Fibrillation Risk
Lim, M. W., Muthalaly, R. G., Wong, G. R., Al‐Kaisey, A., Dey, D., Marwick, T. H., Kistler, P. M., Kalman, J. M., & Nerlekar, N. (2025) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2025.07.020 · Cited by 5
Barison, A., Aquaro, G. D., Dellegrottaglie, S., Rizzo, S., Luca, A. D., Maestrini, V., Scatteia, A., Baggiano, A., Gaspari, M. D., Filardi, P. P., et al. (2025) · Circulation · doi:10.1161/circulationaha.124.072926 · Cited by 5
Research Progress on the Association Between GLP-1 Receptor Agonists and Cardiomyopathy
Yang, X., & Li, X. (2025) · Reviews in Cardiovascular Medicine · doi:10.31083/rcm37180 · Cited by 6
Artificial intelligence in nuclear cardiology: Enhancing diagnostic accuracy and efficiency
Miller, R. J. H., Chareonthaitawee, P., & Slomka, P. J. (2025) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2025.09.010 · Cited by 6
Arrhythmia-Induced Cardiomyopathy in Atrial Fibrillation: Pathogenesis, Diagnosis, and Treatment
Karakasis, P., Theofilis, P., Vlachakis, P. K., Apostolos, A., Ktenopoulos, N., Grigoriou, K., Patoulias, D., Antoniadis, A. P., & Fragakis, N. (2025) · Life · doi:10.3390/life15111675 · Cited by 8
Epicardial Fat Inflammation and GLP-1/GIP Receptor Analogs: Are we Shifting our Perspective?
Iacobellis, G. (2025) · Current Cardiology Reports · doi:10.1007/s11886-025-02325-5 · Cited by 5
Self-citation3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction
Celebi, L. E., & Zorlutuna, P. (2026) · Advanced Science · doi:10.1002/advs.202516114 · Cited by 5
Cooling Down Inflammation in the Cardiovascular System via the Nicotinic Acetylcholine Receptor
Kaplan, A., Lakkis, B., El‐Samadi, L., Karaayvaz, E. B., Booz, G. W., & Zouein, F. A. (2023) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000001455 · Cited by 5
Gastric Submucosal Fat Accumulation Is Associated with Insulin Resistance in Patients with Obesity
Lu, T., Kan, J., He, X., Zou, J., Sheng, D., Xue, Y., Wang, Y., & Xu, L. (2024) · Obesity Surgery · doi:10.1007/s11695-023-07014-2 · Cited by 5
FM-Net: A Fully Automatic Deep Learning Pipeline for Epicardial Adipose Tissue Segmentation
Feng, F., Carlhäll, C., Tan, Y., Agrawal, S., Lundberg, P., Bai, J., Yang, J. Z., Trew, M. L., & Zhao, J. (2024) · Lecture notes in computer science · doi:10.1007/978-3-031-52448-6_9 · Cited by 6
Ren, Y., Chen, L., Liu, J., Wu, Y., Du, X., Li, M., & Lu, Y. (2024) · International Journal of Cardiology · doi:10.1016/j.ijcard.2024.132016 · Cited by 5
Zhang, X., Bao, S., Wang, M., Xu, Z., Yan, F., & Yang, W. (2024) · European Journal of Radiology · doi:10.1016/j.ejrad.2024.111545 · Cited by 5
Bialobroda, J., Bouazizi, K., Ponnaiah, M., Kachenoura, N., Charpentier, E., Zarai, M., Clément, K., Andréelli, F., Aron‐Wisnewsky, J., Hatem, S. N., et al. (2024) · European Heart Journal - Imaging Methods and Practice · doi:10.1093/ehjimp/qyae057 · Cited by 5
Cacciapuoti, F., Mauro, C., D’Andrea, D., Capone, V., Liguori, C., & Cacciapuoti, F. (2024) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0000000000001652 · Cited by 5
Metadata
- Authors
- Iacobellis, G.
- Affiliations
- University of Miami (US)
- Corresponding author
- Iacobellis, Gianluca
- ORCID
- Iacobellis, Gianluca
- Venue
- Nature Reviews Cardiology
- Published
- 2022-03-16
- Volume
- 19
- Issue
- 9
- Pages
- 593-606
- ISSN
- 1759-5002 (ISSN-L)
- 1759-5010
- PMC
- PMC8926097
- OpenAlex
- W4220961850
- Cited by
- 797
- References
- 161
- Citations by year
- 2026: 195 · 2025: 236 · 2024: 214 · 2023: 118 · 2022: 32
- FWCI
- 31.35
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Nature Reviews Cardiology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Fibrosis and Remodeling
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
- Keywords
- epicardial adipose tissue, coronary artery disease, atrial fibrillation, heart failure, brown fat thermogenesis, inflammatory cytokines, profibrotic cytokines, GLP-1 receptor agonists, SGLT2 inhibitors, cardiovascular risk factors
- MeSH terms
- COVID-19, Adipose Tissue, Atrial Fibrillation, Cardiology, Humans, Pericardium
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review