Long-range enhancer–promoter contacts in gene expression control

An integrated encyclopedia of DNA elements in the human genome

The ENCODE Project Consortium (2012) · Nature · doi:10.1038/nature11247 · Cited by 18,072

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

Rao, S. S. P., Huntley, M. H., Durand, N. C., Stamenova, E. K., Bochkov, I. D., Robinson, J. T., Sanborn, A. L., Machol, I., Omer, A. D., Lander, E. S., et al. (2014) · Cell · doi:10.1016/j.cell.2014.11.021 · Cited by 9,212

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

Lieberman-Aiden, E., van Berkum, N. L., Williams, L., Imakaev, M., Ragoczy, T., Telling, A., Amit, I., Lajoie, B. R., Sabo, P. J., Dorschner, M. O., et al. (2009) · Science · doi:10.1126/science.1181369 · Cited by 8,898

Topological domains in mammalian genomes identified by analysis of chromatin interactions

Dixon, J. R., Selvaraj, S., Yue, F., Kim, A., Li, Y., Shen, Y., Hu, M., Liu, J. S., & Ren, B. (2012) · Nature · doi:10.1038/nature11082 · Cited by 6,829

Histone H3K27ac separates active from poised enhancers and predicts developmental state

Creyghton, M. P., Cheng, A. W., Welstead, G. G., Kooistra, T., Carey, B. W., Steine, E. J., Hanna, J., Lodato, M. A., Frampton, G. M., Sharp, P. A., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1016071107 · Cited by 4,302

Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

Maurano, M. T., Humbert, R., Rynes, E., Thurman, R. E., Haugen, E., Wang, H., Reynolds, A. P., Sandstrom, R., Qu, H., Brody, J., et al. (2012) · Science · doi:10.1126/science.1222794 · Cited by 3,716

Capturing Chromosome Conformation

Dekker, J., Rippe, K., Dekker, M., & Kleckner, N. (2002) · Science · doi:10.1126/science.1067799 · Cited by 3,652

Spatial partitioning of the regulatory landscape of the X-inactivation centre

Nora, E. P., Lajoie, B. R., Schulz, E. G., Giorgetti, L., Okamoto, I., Servant, N., Piolot, T., van Berkum, N. L., Meisig, J., Sedat, J., et al. (2012) · Nature · doi:10.1038/nature11049 · Cited by 2,895

Coactivator condensation at super-enhancers links phase separation and gene control

Sabari, B. R., Dall’Agnese, A., Boija, A., Klein, I. A., Coffey, E. L., Shrinivas, K., Abraham, B. J., Hannett, N. M., Zamudio, A. V., Manteiga, J. C., et al. (2018) · Science · doi:10.1126/science.aar3958 · Cited by 2,595

A unique chromatin signature uncovers early developmental enhancers in humans

Rada-Iglesias, A., Bajpai, R., Swigut, T., Brugmann, S. A., Flynn, R. A., & Wysocka, J. (2011) · Nature · doi:10.1038/nature09692 · Cited by 2,233

The epigenome under pressure: On regulatory adaptation to chronic stress in the brain

Arzate‐Mejía, R. G., Carullo, N. V. N., & Mansuy, I. M. (2023) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2023.102832 · Cited by 15

Hi-C, a chromatin 3D structure technique advancing the functional genomics of immune cells

Liu, R., Xu, R., Yan, S., Li, P., Jia, C., Sun, H., Sheng, K., Wang, Y., Zhang, Q., Guo, J., et al. (2024) · Frontiers in Genetics · doi:10.3389/fgene.2024.1377238 · Cited by 15

Chromatin profiling identifies chondrocyte-specific Sox9 enhancers important for skeletal development

Ichiyama‐Kobayashi, S., Hata, K., Wakamori, K., Takahata, Y., Murakami, T., Yamanaka, H., Takano, H., Yao, R., Uzawa, N., & Nishimura, R. (2024) · JCI Insight · doi:10.1172/jci.insight.175486 · Cited by 14

Reversible acetylation of HDAC8 regulates cell cycle

Sang, C.-W., Li, X., Liu, J., Chen, Z., Xia, M., Yu, M., & Yu, W. (2024) · EMBO Reports · doi:10.1038/s44319-024-00210-w · Cited by 14

CRISPR screening uncovers a long-range enhancer for ONECUT1 in pancreatic differentiation and links a diabetes risk variant

Kaplan, S. J., Wong, W., Yan, J., Pulecio, J., Cho, H., Li, Q., Zhao, J., Leslie-Iyer, J., Kazakov, J., Murphy, D., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114640 · Cited by 16

Implicating type 2 diabetes effector genes in relevant metabolic cellular models using promoter-focused Capture-C

Wachowski, N. A., Pippin, J. A., Boehm, K. D., Lu, S., Leonard, M. E., Manduchi, E., Parlin, U. W., Wabitsch, M., Chesi, A., Wells, A. D., et al. (2024) · Diabetologia · doi:10.1007/s00125-024-06261-x · Cited by 13

Multiome-wide Association Studies: Novel Approaches for Understanding Diseases

Shao, M., Chen, K., Zhang, S., Tian, M., Shen, Y., Cao, C., & Gu, N. (2024) · Genomics Proteomics & Bioinformatics · doi:10.1093/gpbjnl/qzae077 · Cited by 14

Technologies to study spatial genome organization: beyond 3C

Übelmesser, N., & Papantonis, A. (2019) · Briefings in Functional Genomics · doi:10.1093/bfgp/elz019 · Cited by 13

A modified protocol of Capture-C allows affordable and flexible high-resolution promoter interactome analysis

Golov, A. K., Abashkin, D. A., Kondratyev, N. V., Razin, S. V., Gavrilov, A. A., & Голимбет, В. Е. (2020) · Scientific Reports · doi:10.1038/s41598-020-72496-4 · Cited by 13

A nuclear enterprise: zooming in on nuclear organization and gene expression control in the African trypanosome

Faria, J. R. C. (2021) · Parasitology · doi:10.1017/s0031182020002437 · Cited by 13

Epigenomic links from metabolism—methionine and chromatin architecture

Xiao, Z., & Locasale, J. W. (2021) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2021.01.011 · Cited by 13

The two waves in single-cell 3D genomics

Ulianov, S. V., & Razin, S. V. (2021) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2021.05.021 · Cited by 15

Leveraging three-dimensional chromatin architecture for effective reconstruction of enhancer–target gene regulatory interactions

Salviato, E., Djordjilović, V., Hariprakash, J. M., Tagliaferri, I., Pal, K., & Ferrari, F. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab547 · Cited by 13

Making connections: enhancers in cellular differentiation

Herrmann, J. C., Beagrie, R. A., & Hughes, J. R. (2021) · Trends in Genetics · doi:10.1016/j.tig.2021.10.008 · Cited by 14

Multiple parameters shape the 3D chromatin structure of single nuclei at the doc locus in Drosophila

Götz, M., Messina, O., Espínola, S., Fiche, J.-B., & Nöllmann, M. (2022) · Nature Communications · doi:10.1038/s41467-022-32973-y · Cited by 16

Enhancers are genes that express organizational RNAs

Mattick, J. S. (2023) · Frontiers in RNA Research · doi:10.3389/frnar.2023.1194526 · Cited by 10

Off-target effects of CRISPRa on interleukin-6 expression

Soubeyrand, S., Lau, P., Peters, V., & McPherson, R. (2019) · PLoS ONE · doi:10.1371/journal.pone.0224113 · Cited by 13

Understanding Regulatory Mechanisms of Brain Function and Disease through 3D Genome Organization

Liu, W., Zhong, W., Chen, J. C., Huang, B., Hu, M., & Li, Y. (2022) · Genes · doi:10.3390/genes13040586 · Cited by 11

DNA methylation insulates genic regions from CTCF loops near nuclear specklesPreprint

Roseman, S. A., Siegenfeld, A. P., Lee, C., Lue, N. Z., Waterbury, A. L., & Liau, B. B. (2024) · eLife · doi:10.7554/elife.102930 · Cited by 15

Dose-dependent sensitivity of human 3D chromatin to a heart disease-linked transcription factorPreprint

Grant, Z. L., Kuang, S., Zhang, S., Horrillo, A. J., Rao, K. S., Kameswaran, V., Joubran, C., Lau, P. K., Dong, K., Yang, B., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.09.632202 · Cited by 13

CFA: An explainable deep learning model for annotating the transcriptional roles of cis-regulatory modules based on epigenetic codes

Yang, T.-H., Yu, Y.-H., Wu, S.-H., & Zhang, F. (2022) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2022.106375 · Cited by 12

Network propagation for GWAS analysis: a practical guide to leveraging molecular networks for disease gene discovery

Visonà, G., Bouzigon, E., Démenais, F., & Schweikert, G. (2024) · Briefings in Bioinformatics · doi:10.1093/bib/bbae014 · Cited by 11

RUNX1 C-terminal mutations impair blood cell differentiation by perturbing specific enhancer-promoter networks

Jayne, N. D., Liang, Z., Lim, D., Chen, P. B., Diaz, C., Arimoto, K., Xia, L., Liu, M., Ren, B., Fu, X., et al. (2024) · Blood Advances · doi:10.1182/bloodadvances.2023011484 · Cited by 13

A multi-regional human brain atlas of chromatin accessibility and gene expression facilitates promoter-isoform resolution genetic fine-mapping

Dong, P., Song, L., Bendl, J. M., Misir, R., Shao, Z., Edelstien, J., Davis, D. A., Haroutunian, V. H., Scott, W. K., Acker, S., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-54448-y · Cited by 12

DNALONGBENCH: a benchmark suite for long-range DNA prediction tasks

Cheng, W., Song, Z., Zhang, Y., Wang, S., Wang, D., Yang, M., Li, L., & Ma, J. (2025) · Nature Communications · doi:10.1038/s41467-025-65077-4 · Cited by 20

Advances in higher-order chromatin architecture: the move towards 4D genome

Jung, N., & Kim, T.-K. (2021) · BMB Reports · doi:10.5483/bmbrep.2021.54.5.035 · Cited by 14

Building a Mammalian Retina: An Eye on Chromatin Structure

Daghsni, M., & Aldiri, I. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.775205 · Cited by 11

Epigenetics of spondyloarthritis

Cherqaoui, B., Crémazy, F. G. E., Hue, C., Garchon, H., Bréban, M., & Costantino, F. (2020) · Joint Bone Spine · doi:10.1016/j.jbspin.2020.06.003 · Cited by 12

Computational Modeling of Gene-Specific Transcriptional Repression, Activation and Chromatin Interactions in Leukemogenesis by LASSO-Regularized Logistic Regression

Steinauer, N., Zhang, K., Guo, C. H., & Zhang, J. (2021) · IEEE Transactions on Computational Biology and Bioinformatics · doi:10.1109/tcbb.2021.3078128 · Cited by 12

The non-coding genome in genetic brain disorders: new targets for therapy?

Salsench, E. M., Karkala, F., Lanko, K., & Barakat, T. S. (2021) · Essays in Biochemistry · doi:10.1042/ebc20200121 · Cited by 11

ReFeaFi: Genome-wide prediction of regulatory elements driving transcription initiation

Umarov, R. K., Li, Y., Arakawa, T., Takizawa, S., Gao, X., & Arner, E. (2021) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1009376 · Cited by 12

Long-Range Control of Class Switch Recombination by Transcriptional Regulatory Elements

Dauba, A., & Khamlichi, A. A. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.738216 · Cited by 12

Association of DNA Methylation in Blood Pressure-Related Genes With Ischemic Stroke Risk and Prognosis

Zhang, H., Mo, X., Wang, A., Peng, H. Y., Guo, D., Zhong, C., Zhu, Z., Xu, T., & Zhang, Y. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.796245 · Cited by 12

When 3D genome technology meets viral infection, including SARS‐CoV‐2

Liang, W., Wang, S., Wang, H., Li, X., Meng, Q., Zhao, Y., & Zheng, C. (2022) · Journal of Medical Virology · doi:10.1002/jmv.28040 · Cited by 10

Gene structure heterogeneity drives transcription noise within human chromosomesPreprint

Chiang, M., Brackley, C. A., Naughton, C., Nozawa, R., Battaglia, C., Marenduzzo, D., & Gilbert, N. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.06.09.495447 · Cited by 11

The GRN concept as a guide for evolutionary developmental biology

Feigin, C. Y., Li, S., Moreno, J. A., & Mallarino, R. (2022) · Journal of Experimental Zoology Part B Molecular and Developmental Evolution · doi:10.1002/jez.b.23132 · Cited by 14

Genome analysis reveals hepatic transcriptional reprogramming changes mediated by enhancers during chick embryonic development

Sun, X., Wang, Y., Wang, C., Wang, Y., Ren, Z., Yang, X., Yang, X., & Liu, Y. (2023) · Poultry Science · doi:10.1016/j.psj.2023.102516 · Cited by 12

A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival

Abassah‐Oppong, S., Zoia, M., Mannion, B. J., Rouco, R., Tissières, V., Spurrell, C. H., Roland, V., Darbellay, F., Itum, A., Gamart, J., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-53009-7 · Cited by 15

Active enhancers: recent research advances and insights into disease

Zhang, J., Wang, Q., Liu, J., Duan, Y., Liu, Z., Zhang, Z., & Li, C. (2024) · Biology Direct · doi:10.1186/s13062-024-00559-x · Cited by 18

Long G4-rich enhancers target promoters via a G4 DNA-based mechanism

DeMeis, J. D., Roberts, J. T., Delcher, H. A., Godang, N. L., Coley, A. B., Brown, C. L., Shaw, M. H., Naaz, S., Dahal, A., Alqudah, S. Y., et al. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae1180 · Cited by 15

The emerging roles of long non-coding RNAs in the nervous system

Altaf, S., Cummins, M. J., Ittner, L. M., & Mattick, J. S. (2025) · Nature reviews. Neuroscience · doi:10.1038/s41583-025-00960-z · Cited by 18

A gene-level methylome-wide association analysis identifies novel Alzheimer’s disease genes

Wu, C., Bradley, J. R., Li, Y., Wu, L., & Deng, H. (2021) · Bioinformatics · doi:10.1093/bioinformatics/btab045 · Cited by 11

New insights into promoter–enhancer communication mechanisms revealed by dynamic single-molecule imaging

Li, J., & Pertsinidis, A. (2021) · Biochemical Society Transactions · doi:10.1042/bst20200963 · Cited by 10

Epigenome rewiring in human pluripotent stem cells

Yan, J., & Huangfu, D. (2021) · Trends in Cell Biology · doi:10.1016/j.tcb.2021.12.001 · Cited by 11

Interplay between epigenome and 3D chromatin structure

Han, M.-H., Issagulova, D., & Park, M. (2023) · BMB Reports · doi:10.5483/bmbrep.2023-0197 · Cited by 13

Exact results for gene-expression models with general waiting-time distributions

Zhang, J., Chen, A., Qiu, H., Zhang, J., Tian, T., & Zhou, T. (2024) · Physical review. E · doi:10.1103/physreve.109.024119 · Cited by 12

Recently Evolved Enhancers Emerge with High Interindividual Variability and Less Frequently Associate with Disease

Castelijns, B., Baak, M. L., Geeven, G., Vermunt, M. W., Wiggers, C. R. M., Timpanaro, I. S., Kondova, I. I., de Laat, W. L., & Creyghton, M. P. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.107799 · Cited by 11

Genetic Prioritization, Therapeutic Repositioning and Cross-Disease Comparisons Reveal Inflammatory Targets Tractable for Kidney Stone Disease

Fang, H., & Jiang, L. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.687291 · Cited by 11

A Shift in Paradigms: Spatial Genomics Approaches to Reveal Single-Cell Principles of Genome Organization

Gizzi, A. M. C. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.780822 · Cited by 13

CREaTor: zero-shot cis-regulatory pattern modeling with attention mechanisms

Li, Y., Ju, F., Chen, Z., Qu, Y., Xia, H., He, L., Wu, L., Zhu, J., Shao, B., & Deng, P. (2023) · Genome Biology · doi:10.1186/s13059-023-03103-8 · Cited by 12

PiER: web-based facilities tailored for genetic target prioritisation harnessing human disease genetics, functional genomics and protein interactions

Fang, H. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac379 · Cited by 10

The histone methyltransferase KMT2D is essential for embryo implantation via regulating precise differentiation of endometrial cells

Kobayashi, R., Tajika, Y., Kohmaru, J., Morita, S., Horii, T., Mizukami, Y., Aikawa, S., Hirota, Y., & Hatada, I. (2024) · Cell Death Discovery · doi:10.1038/s41420-024-02134-9 · Cited by 10

Genome-wide chromosome architecture prediction reveals biophysical principles underlying gene structure

Chiang, M., Brackley, C. A., Naughton, C., Nozawa, R., Battaglia, C., Marenduzzo, D., & Gilbert, N. (2024) · Cell Genomics · doi:10.1016/j.xgen.2024.100698 · Cited by 10

Unveiling genetic signatures of immune response in immune-related diseases through single-cell eQTL analysis across diverse conditions

Zhang, Z., Li, W., Zhan, Q., Aillaud, M., Botey-Bataller, J., Zoodsma, M., ter Horst, R., Joosten, L. A. B., Bock, C., Schulte, L. N., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-61192-4 · Cited by 11

Cohesin prevents local mixing of condensed euchromatic domains in living human cells

Shimazoe, M. A., Iida, S., Minami, K., Higashi, K., Tamura, S., Kobayashi, Y., Fujishiro, S., Xiong, L., Nakazato, K., Ashwin, S. S., et al. (2026) · Nature Genetics · doi:10.1038/s41588-026-02736-2 · Cited by 12

Interrogating the regulatory epigenome of cellular senescence

Thanos, D.-F., Ntintas, O. A., Athanasiadis, E. I., Papaspyropoulos, A., Petty, R., & Gorgoulis, V. G. (2025) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-025-05848-w · Cited by 10

Deregulation of enhancer structure, function, and dynamics in acute lymphoblastic leukemia

Belver, L., Alberó, R., & Ferrando, A. A. (2021) · Trends in Immunology · doi:10.1016/j.it.2021.03.005 · Cited by 13

Functional annotation of breast cancer risk loci: current progress and future directions

Cardoso, S. R., Gillespie, A., Haider, S. A., & Fletcher, O. (2021) · British Journal of Cancer · doi:10.1038/s41416-021-01612-6 · Cited by 10

Fluorescent labeling of genomic loci in Drosophila imaginal discs with heterologous DNA-binding proteins

Delker, R. K., Munce, R. H., Hu, M., & Mann, R. S. (2022) · Cell Reports Methods · doi:10.1016/j.crmeth.2022.100175 · Cited by 12

Can aggressive cancers be identified by the “aggressiveness” of their chromatin?

Gurova, K. V. (2022) · BioEssays · doi:10.1002/bies.202100212 · Cited by 9

Comprehensive characterization of enhancer RNA in hepatocellular carcinoma reveals three immune subtypes with implications for immunotherapy

Bu, X., Liu, S., Wen, D., Kan, A., Xu, Y., Lin, X., & Shi, M. (2022) · Molecular Therapy — Oncolytics · doi:10.1016/j.omto.2022.07.001 · Cited by 10

Factors and Mechanisms That Influence Chromatin-Mediated Enhancer–Promoter Interactions and Transcriptional Regulation

Ito, S., Das, N. D., Umehara, T., & Koseki, H. (2022) · Cancers · doi:10.3390/cancers14215404 · Cited by 13

A novel intergenic enhancer that regulates Bdnf expression in developing cortical neurons

Brookes, E., Cruz, B. M. D. L., Boulasiki, P., Au, H. Y. A., Varsally, W., Barrington, C., Hadjur, S., & Riccio, A. (2022) · iScience · doi:10.1016/j.isci.2022.105695 · Cited by 13

Strategies for activity analysis of single nucleotide polymorphisms associated with human diseases

Ren, N., Dai, S., Ma, S., & Yang, F. (2022) · Clinical Genetics · doi:10.1111/cge.14282 · Cited by 12

3D genomic organization in cancers

Wang, J., Tao, H., Li, H., Bo, X., & Chen, H. (2023) · Quantitative Biology · doi:10.15302/j-qb-022-0317 · Cited by 10

Epigenomic perturbation of novel EGFR enhancers reduces the proliferative and invasive capacity of glioblastoma and increases sensitivity to temozolomide

Vincent, C. A., Nissen, I., Dakhel, S., Hörnblad, A., & Remeseiro, S. (2023) · BMC Cancer · doi:10.1186/s12885-023-11418-9 · Cited by 10

Pan-Cancer Analysis of Head-to-Head Gene Pairs in Terms of Transcriptional Activity, Co-expression and Regulation

Chen, Y., Li, H., Li, Y., & Li, Y. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2020.560997 · Cited by 10

Quantifying RNA synthesis at rate-limiting steps of transcription using nascent RNA-sequencing data

Rabenius, A., Chandrakumaran, S., Sistonen, L., & Vihervaara, A. (2022) · STAR Protocols · doi:10.1016/j.xpro.2021.101036 · Cited by 10

Identification of a distal enhancer that determines the expression pattern of acute phase marker C-reactive protein

Wang, M., Zhang, C., Zhou, H., Ge, Z.-B., Su, C.-C., Lou, Z.-H., Zhang, X., Xu, T., Li, S., Zhu, L., et al. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102160 · Cited by 10

A comprehensive revisit of the machine‐learning tools developed for the identification of enhancers in the human genome

Phan, L. T., Oh, C., He, T., & Manavalan, B. (2023) · PROTEOMICS · doi:10.1002/pmic.202200409 · Cited by 11

Mechanistic Dissection of RNA-Binding Proteins in Regulated Gene Expression at Chromatin LevelsPreprint

Chen, J., Lim, D., & Fu, X. (2019) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2019.84.039222 · Cited by 10

Regulatory Landscapes of Nppa and Nppb

Sobreira, D. R., & Nóbrega, M. A. (2021) · Circulation Research · doi:10.1161/circresaha.120.318495 · Cited by 10

KMT2D haploinsufficiency in Kabuki syndrome disrupts neuronal function through transcriptional and chromatin rewiring independent of H3K4-monomethylationPreprint

Gabriele, M., Vitriolo, A., Cuvertino, S., Pereira, M. F., Franconi, C., Germain, P., Capocefalo, D., Castaldi, D., Tenderini, E., Bèchet, N. B., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.04.22.440945 · Cited by 10

HNF4A guides the MLL4 complex to establish and maintain H3K4me1 at gene regulatory elements

Thakur, A., Park, K., Cullum, R., Fuglerud, B. M., Khoshnoodi, M., Drissler, S., Stephan, T. L., Lotto, J., Kim, D., Gonzalez, F. J., et al. (2024) · Communications Biology · doi:10.1038/s42003-024-05835-0 · Cited by 10

Making Biological Sense of Genetic Studies of Age-Related Macular Degeneration

Singh, N., Swaroop, A., & Ratnapriya, R. (2021) · Advances in Experimental Medicine and Biology · doi:10.1007/978-3-030-66014-7_8 · Cited by 11

Three‐Dimensional Chromosomal Landscape Revealing miR ‐146a Dysfunctional Enhancer in Lupus and Establishing a CRISPR‐Mediated Approach to Inhibit the Interferon Pathway

Zhu, X., Zhang, Y., Yin, Z., Ye, Z., Qin, Y., Cheng, Z., Shen, Y., Yin, Z., Ma, J., Tang, Y., et al. (2023) · Arthritis & Rheumatology · doi:10.1002/art.42703 · Cited by 10

Benzo[a]pyrene exposure affects colorectal cancer susceptibility by regulating ERβ-mediated LINC02977 transcription

Ben, S., Li, S., Gu, D., Zhao, L., Xu, S., Ding, Z., Chen, S., Cheng, Y., Xin, J., Du, M., et al. (2024) · Environment International · doi:10.1016/j.envint.2024.108443 · Cited by 11

Powdery mildew-induced changes in phyllosphere microbial community dynamics of cucumber

Yue, C., Du, C., Wang, X., et al. (2024) · FEMS Microbiology Ecology · doi:10.1093/femsec/fiae050 · Cited by 9

Physical and functional interaction among Irf8 enhancers during dendritic cell differentiation

Yamasaki, T., Nishiyama, A., Kurogi, N., Nishimura, K., Nishida, S., Kurotaki, D., Ban, T., Ramilowski, J. A., Ozato, K., Toyoda, A., et al. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114107 · Cited by 8

Integrative analysis of the 3D genome and epigenome in mouse embryonic tissues

Yu, M., Zemke, N. R., Chen, Z., Jurić, I., Hu, R., Raviram, R., Abnousi, A., Fang, R., Zhang, Y., Gorkin, D. U., et al. (2024) · Nature Structural & Molecular Biology · doi:10.1038/s41594-024-01431-2 · Cited by 9

Identification of a distal enhancer of Ucp1 essential for thermogenesis and mitochondrial function in brown fat

Su, D., Jiang, T., Song, Y., Li, D., Zhan, S., Zhong, T., Guo, J., Li, L., Zhang, H., & Wang, L. (2025) · Communications Biology · doi:10.1038/s42003-025-07468-3 · Cited by 12

Roles for the 3D genome in the cell cycle, DNA replication, and double strand break repair

Giles, K. A., Taberlay, P. C., Cesare, A. J., & Jones, M. V. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1548946 · Cited by 11

Super-enhancer-hijacking RBBP7 potentiates metastasis and stemness of breast cancer via recruiting NuRD complex subunit LSD1

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Genomic regions occupied by both RARα and VDR are involved in the convergence and cooperation of retinoid and vitamin D signaling pathways

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