Schoenfelder, Stefan

Single-cell Hi-C reveals cell-to-cell variability in chromosome structure

Nagano, T., Lubling, Y., Stevens, T. J., Schoenfelder, S., Yaffe, E., Dean, W., Laue, E. D., Tanay, A., & Fraser, P. (2013) · Nature

Genomics and Chromatin DynamicsGenomic variations and chromosomal abnormalities

Cited by 1,589

Long-range enhancer–promoter contacts in gene expression control

Schoenfelder, S., & Fraser, P. (2019) · Nature Reviews Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 1,102

Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C

Mifsud, B., Tavares-Cadete, F., Young, A. N., Sugar, R., Schoenfelder, S., Ferreira, L., Wingett, S. W., Andrews, S., Grey, W., Ewels, P. A., et al. (2015) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 990

Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins

Wutz, G., Várnai, C., Nagasaka, K., Cisneros, D. A., Stocsits, R. R., Tang, W., Schoenfelder, S., Jessberger, G., Muhar, M., Hossain, M. J., et al. (2017) · The EMBO Journal

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 864

The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements

Schoenfelder, S., Furlan-Magaril, M., Mifsud, B., Tavares-Cadete, F., Sugar, R., Javierre, B.-M., Nagano, T., Katsman, Y., Sakthidevi, M., Wingett, S. W., et al. (2015) · Genome Research

Genomics and Chromatin DynamicsChromosomal and Genetic Variations

Cited by 460

CHiCAGO: robust detection of DNA looping interactions in Capture Hi-C data

Cairns, J., Freire-Pritchett, P., Wingett, S. W., Várnai, C., Dimond, A., Plagnol, V., Zerbino, D., Schoenfelder, S., Javierre, B.-M., Osborne, C., et al. (2016) · Genome Biology

Genomics and Chromatin DynamicsBioinformatics and Genomic Networks

Cited by 417

Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome

Schoenfelder, S., Sugar, R., Dimond, A., Javierre, B.-M., Armstrong, H., Mifsud, B., Dimitrova, E., Matheson, L., Tavares-Cadete, F., Furlan-Magaril, M., et al. (2015) · Nature Genetics

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 398

Global reorganization of the nuclear landscape in senescent cells

Chandra, T., Ewels, P. A., Schoenfelder, S., Furlan-Magaril, M., Wingett, S. W., Kirschner, K., Thuret, J.-Y., Andrews, S., Fraser, P., & Reik, W. (2015) · Cell Reports

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 348

Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci

Martin, P., McGovern, A., Orozco, G., Duffus, K., Yarwood, A., Schoenfelder, S., Cooper, N. J., Barton, A., Wallace, C., Fraser, P., et al. (2015) · Nature Communications

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 213

Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours

Harewood, L., Kishore, K., Eldridge, M. D., Wingett, S., Pearson, D., Schoenfelder, S., Collins, V. P., & Fraser, P. (2017) · Genome Biology

Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms

Cited by 178

Cohesin-Dependent and -Independent Mechanisms Mediate Chromosomal Contacts between Promoters and Enhancers

Thiecke, M. J., Wutz, G., Muhar, M., Tang, W., Bevan, S., Malysheva, V., Stocsits, R., Neumann, T., Zuber, J., Fraser, P., et al. (2020) · Cell Reports

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 177

Comparison of Hi-C results using in-solution versus in-nucleus ligation

Nagano, T., Várnai, C., Schoenfelder, S., Javierre, B.-M., Wingett, S. W., & Fraser, P. (2015) · Genome Biology

Genomics and Chromatin DynamicsChromosomal and Genetic Variations

Cited by 166

Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells

Freire-Pritchett, P., Schoenfelder, S., Várnai, C., Wingett, S. W., Cairns, J., Collier, A. J., García-Vílchez, R., Furlan-Magaril, M., Osborne, C. S., Fraser, P., et al. (2017) · eLife

Genomics and Chromatin DynamicsPluripotent Stem Cells Research

Cited by 161

Long-Range Enhancer Interactions Are Prevalent in Mouse Embryonic Stem Cells and Are Reorganized upon Pluripotent State Transition

Novo, C. L., Javierre, B.-M., Cairns, J., Segonds-Pichon, A., Wingett, S. W., Freire-Pritchett, P., Furlan-Magaril, M., Schoenfelder, S., Fraser, P., & Rugg-Gunn, P. J. (2018) · Cell Reports

Genomics and Chromatin DynamicsPluripotent Stem Cells Research

Cited by 119

Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence

Olan, I., Parry, A. J., Schoenfelder, S., Narita, M., Ito, Y., Chan, A. S. L., Slater, G. S. C., Bihary, D., Bando, M., Shirahige, K., et al. (2020) · Nature Communications

Genomics and Chromatin DynamicsTelomeres, Telomerase, and Senescence

Cited by 76

Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages

Schoenfelder, S., Mifsud, B., Senner, C. E., Todd, C. D., Chrysanthou, S., Darbo, E., Hemberger, M., & Branco, M. R. (2018) · Nature Communications

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 54

Thrombopoietin signaling to chromatin elicits rapid and pervasive epigenome remodeling within poised chromatin architectures

Comoglio, F., Park, H. J., Schoenfelder, S., Barozzi, I., Bode, D., Fraser, P., & Green, A. R. (2018) · Genome Research

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 41

Locus-specific induction of gene expression from heterochromatin loci during cellular senescence

Tomimatsu, K., Bihary, D., Olan, I., Parry, A. J., Schoenfelder, S., Chan, A. S. L., Slater, G. S. C., Ito, Y., Rugg-Gunn, P. J., Kirschner, K., et al. (2021) · Nature Aging

Genomics and Chromatin DynamicsTelomeres, Telomerase, and Senescence

Cited by 25