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Cited by 259

The DOI matches its Crossref record; 229 of the 229 references it cites were found in a registry or an index.

Incongruence in the phylogenomics era

Open access
Steenwyk, Jacob L., Li, Yuanning, Zhou, Xiaofan, Shen, Xing-Xing, Rokas, Antonis·2023·Nature Reviews Genetics

Abstract

Genome-scale data and the development of novel statistical phylogenetic approaches have greatly aided the reconstruction of a broad sketch of the tree of life and resolved many of its branches. However, incongruence — the inference of conflicting evolutionary histories — remains pervasive in phylogenomic data, hampering our ability to reconstruct and interpret the tree of life. Biological factors, such as incomplete lineage sorting, horizontal gene transfer, hybridization, introgression, recombination and convergent molecular evolution, can lead to gene phylogenies that differ from the species tree. In addition, analytical factors, including stochastic, systematic and treatment errors, can drive incongruence. Here, we review these factors, discuss methodological advances to identify and handle incongruence, and highlight avenues for future research. Incongruence occurs when phylogenetic trees show conflicting evolutionary histories such as patterns of branching or relationships among taxa. This Review discusses the biological and analytical factors that lead to incongruence, methodological advances to identify and resolve incongruence, and avenues for future research.

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Metadata

Authors
Steenwyk, J. L., Li, Y., Zhou, X., Shen, X.-X., & Rokas, A.
Venue
Nature Reviews Genetics
Published
2023-06-27
Volume
24
Issue
12
Pages
834-850
ISSN
  • 1471-0056 (ISSN-L)
  • 1471-0064
OpenAlex
W4382248980
Cited by
259
References
229
FWCI
6.47
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Incongruence in the phylogenomics era. https://app.cochat.ai/papers/10.1038/s41576-023-00620-x
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Steenwyk, J. L., Li, Y., Zhou, X., Shen, X.-X., & Rokas, A. (2023). Incongruence in the phylogenomics era. Nature Reviews Genetics. https://doi.org/10.1038/s41576-023-00620-x

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