Chronic kidney disease and the global public health agenda: an international consensus
Open accessAbstract
Early detection is a key strategy to prevent kidney disease, its progression and related complications, but numerous studies show that awareness of kidney disease at the population level is low. Therefore, increasing knowledge and implementing sustainable solutions for early detection of kidney disease are public health priorities. Economic and epidemiological data underscore why kidney disease should be placed on the global public health agenda - kidney disease prevalence is increasing globally and it is now the seventh leading risk factor for mortality worldwide. Moreover, demographic trends, the obesity epidemic and the sequelae of climate change are all likely to increase kidney disease prevalence further, with serious implications for survival, quality of life and health care spending worldwide. Importantly, the burden of kidney disease is highest among historically disadvantaged populations that often have limited access to optimal kidney disease therapies, which greatly contributes to current socioeconomic disparities in health outcomes. This joint statement from the International Society of Nephrology, European Renal Association and American Society of Nephrology, supported by three other regional nephrology societies, advocates for the inclusion of kidney disease in the current WHO statement on major non-communicable disease drivers of premature mortality.
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Chronic kidney disease affects over 10% of the global population.
“Chronic kidney disease (CKD) is a disorder of the loss of kidney function that affects over 10% of the global population [54].”
Cites
Vos, T., Lim, S. S., Abbafati, C., Abbas, K. M., Abbasi, M., Abbasifard, M., Abbasi-Kangevari, M., Abbastabar, H., Abd-Allah, F., Abdelalim, A., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30925-9 · Cited by 19,358 · see citing works
Self-citation2021 ESC Guidelines on cardiovascular disease prevention in clinical practice
Visseren, F. L. J., Mach, F., Smulders, Y. M., Carballo, D., Koskinas, K. C., Bäck, M., Benetos, A., Biffi, A., Boavida, J.-M., Capodanno, D., et al. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehab484 · Cited by 6,485 · see citing works
Self-citationVollset, S. E., Goren, E., Yuan, C.-W., Cao, J., Smith, A. E., Hsiao, T., Bisignano, C., Azhar, G. S., Castro, E., Chalek, J., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30677-2 · Cited by 1,506 · see citing works
Baigent, C., Emberson, J., Haynes, R., Herrington, W. G., Judge, P., Landray, M. J., Mayne, K. J., Ng, S. Y. A., Preiss, D., Roddick, A. J., et al. (2022) · The Lancet · doi:10.1016/s0140-6736(22)02074-8 · Cited by 1,020 · see citing works
Self-citationGlobal epidemiology of end-stage kidney disease and disparities in kidney replacement therapy
Thurlow, J. S., Joshi, M., Yan, G., Norris, K. C., Agodoa, L. Y., Yuan, C. M., & Nee, R. (2021) · American Journal of Nephrology · doi:10.1159/000514550 · Cited by 855 · see citing works
Fletcher, B. R., Damery, S., Aiyegbusi, O. L., Anderson, N., Calvert, M., Cockwell, P., Ferguson, J., Horton, M., Paap, M. C. S., Sidey-Gibbons, C., et al. (2022) · PLOS Medicine · doi:10.1371/journal.pmed.1003954 · Cited by 414 · see citing works
James, M. T., Grams, M. E., Woodward, M., Elley, C. R., Green, J. A., Wheeler, D. C., de Jong, P., Gansevoort, R. T., Levey, A. S., Warnock, D. G., et al. (2015) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2015.02.338 · Cited by 309 · see citing works
Crump, C., Sundquist, J., Winkleby, M. A., & Sundquist, K. (2019) · BMJ · doi:10.1136/bmj.l1346 · Cited by 265 · see citing works
Crosstalk between the nervous system and the kidney
Tanaka, S., & Okusa, M. D. (2020) · Kidney International · doi:10.1016/j.kint.2019.10.032 · Cited by 160 · see citing works
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Spinelli, J. C., Suleski, B. J., Wright, D. E., Grow, J. L., Fagans, G. R., Buckley, M. J., Yang, D. S., Yang, K., Beil, S. M., Wallace, J. C., et al. (2025) · npj Digital Medicine · doi:10.1038/s41746-025-01466-9 · Cited by 44 · see citing works
Hu, X., Yu, S.-J., Gao, Y.-C., Zhao, Y., He, Y.-S., Liu, Y.-C., Pan, H.-F., & Wang, P. (2025) · BMC Geriatrics · doi:10.1186/s12877-025-06344-3 · Cited by 15 · see citing works
Stadt, M. M., & Layton, A. T. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.01.651663
“Chronic kidney disease (CKD) is a disorder of the loss of kidney function that affects over 10% of the global population [54].”
- Authors
- Francis, A., Harhay, M. N., Ong, A. C. M., Tummalapalli, S. L., Ortiz, A., Fogo, A. B., Fliser, D., Roy-Chaudhury, P., Fontana, M., Nangaku, M., Wanner, C., Malik, C., Hradsky, A., Adu, D., Bavanandan, S., Cusumano, A., Sola, L., Ulasi, I., Jha, V., American Society of Nephrology, European Renal Association, & International Society of Nephrology
- Affiliations
- Children's Health Queensland Hospital and Health Service (AU)
- Drexel University (US)
- University of Sheffield (GB)
- Weill Cornell Medicine (US)
- Vanderbilt University Medical Center (US)
- Universitätsklinikum des Saarlandes (DE)
- University of Tokyo Hospital (JP)
- Universitätsklinikum Würzburg (DE)
- International Society of Nephrology (BE)
- University of Ghana (GH)
- Hospital Kuala Lumpur (MY)
- University of Nigeria Teaching Hospital (NG)
- Manipal Academy of Higher Education (IN)
- Corresponding author
- Jha, Vivekanand
- ORCID
- Venue
- Nature Reviews Nephrology
- Published
- 2024-04-03
- Volume
- 20
- Issue
- 7
- Pages
- 473-485
- ISSN
- 1745-8323 (ISSN-L)
- 1759-5061
- 1759-507X
- OpenAlex
- W4393854155
- Cited by
- 1,374
- References
- 9
- Citations by year
- 2026: 599 · 2025: 656 · 2024: 119
- FWCI
- 89.43
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Nature Reviews Nephrology (publishedVersion)
- PubMed (publishedVersion)
- White Rose Research Online (University of Leeds, The University of Sheffield, University of York) (acceptedVersion, other-oa)
- Funders
- American Society of Nephrology
- World Heart Federation
- Topics
- Health Sciences › Medicine › Nephrology › Chronic Kidney Disease and Diabetes
- Health Sciences › Medicine › Nephrology › Dialysis and Renal Disease Management
- Health Sciences › Medicine › Nephrology › Acute Kidney Injury Research
- Keywords
- chronic kidney disease, early detection, non-communicable diseases, premature mortality, socioeconomic disparities, health equity, obesity, climate change, kidney disease prevalence, health care spending
- MeSH terms
- Humans, Public Health, Risk Factors, Global Health, Consensus, Renal Insufficiency, Chronic
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