Genomic basis of geographical adaptation to soil nitrogen in rice
Abstract
The intensive application of inorganic nitrogen underlies marked increases in crop production, but imposes detrimental effects on ecosystems 1,2: it is therefore crucial for future sustainable agriculture to improve the nitrogen-use efficiency of crop plants. Here we report the genetic basis of nitrogen-use efficiency associated with adaptation to local soils in rice (Oryza sativa L.). Using a panel of diverse rice germplasm collected from different ecogeographical regions, we performed a genome-wide association study on the tillering response to nitrogen-the trait that is most closely correlated with nitrogen-use efficiency in rice-and identified OsTCP19 as a modulator of this tillering response through its transcriptional response to nitrogen and its targeting to the tiller-promoting gene DWARF AND LOW-TILLERING (DLT)3,4. A 29-bp insertion and/or deletion in the OsTCP19 promoter confers a differential transcriptional response and variation in the tillering response to nitrogen among rice varieties. The allele of OsTCP19 associated with a high tillering response to nitrogen is prevalent in wild rice populations, but has largely been lost in modern cultivars: this loss correlates with increased local soil nitrogen content, which suggests that it might have contributed to geographical adaptation in rice. Introgression of the allele associated with a high tillering response into modern rice cultivars boosts grain yield and nitrogen-use efficiency under low or moderate levels of nitrogen, which demonstrates substantial potential for rice breeding and the amelioration of negative environment effects by reducing the application of nitrogen to crops.
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Biochemical conversion converts biomass into liquid fuels, natural gas, bio-products, and chemical building blocks using microbes and enzymes as catalysts.
“Biochemical conversion converts biomass into liquid fuels (e.g., alcohols and alkanes), natural gas (e.g., hydrogen and methane), different types of bio-products (e.g., carotenoids, omega-3 and omega-6 fatty acids), as well as other chemical building blocks (e.g., acetic acid and lactic acid) using microbes and enzymes as the catalyst.66”
From Technologies and perspectives for achieving carbon neutrality (2021) · cites this paper as [66]
Introduction of proliferating cell factor domain proteins such as OsTCP19-H into modern rice varieties has been shown to enhance NUE.
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From Technologies and perspectives for achieving carbon neutrality (2021) · cites this paper as [66]
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Technologies and perspectives for achieving carbon neutrality
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Self-citation
- Authors
- Liu, Y., Wang, H., Jiang, Z., Wang, W., Xu, R., Wang, Q., Zhang, Z., Li, A., Liang, Y., Ou, S., Liu, X., Cao, S., Tong, H., Wang, Y., Zhou, F., Liao, H., Hu, B., & Chu, C.
- Affiliations
- Chinese Academy of Sciences (CN)
- South China Agricultural University (CN)
- Peking University (CN)
- Chinese Academy of Agricultural Sciences (CN)
- Corresponding author
- Hu, Bin
- Chu, Chengcai
- ORCID
- Venue
- Nature
- Published
- 2021-01-06
- Volume
- 590
- Issue
- 7847
- Pages
- 600-605
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W3119006924
- Cited by
- 468
- References
- 41
- Citations by year
- 2026: 72 · 2025: 91 · 2024: 98 · 2023: 90 · 2022: 79 · 2021: 38
- FWCI
- 47.46
- Type
- journal article
- Language
- en
- Update notices
- correction (2022-09-23)
- Open access
- closed
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Rice Cultivation and Yield Improvement
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Mapping and Diversity in Plants and Animals
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant nutrient uptake and metabolism
- Keywords
- rice, nitrogen use efficiency, geographical adaptation, soil nitrogen, introgression, grain yield, sustainable agriculture
- MeSH terms
- Genetic Introgression, Adaptation, Physiological, Alleles, Epistasis, Genetic, Nitrogen, Plant Proteins, Promoter Regions, Genetic, Oryza, Soil, Genetic Variation, Gene Expression Regulation, Plant, Crops, Agricultural, INDEL Mutation, Genome-Wide Association Study
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