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Analytical and biomedical applications of microfluidics in traditional Chinese medicine research

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3D printed microfluidics for cell biological applications

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Alliance of Heart and Endoderm: Multilineage Organoids to Model Co-development

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Engineering human immune organoids for translational immunology

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Establishment of advanced tumor organoids with emerging innovative technologies

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Modeling the human maternal-fetal interface

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Array Tomography Workflow for the Targeted Acquisition of Volume Information using Scanning Electron Microscopy

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Integration of Patient-Derived Organoids and Organ-on-Chip Systems: Investigating Colorectal Cancer Invasion within the Mechanical and GABAergic Tumor MicroenvironmentPreprint

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From Cancer to Immune Organoids: Innovative Preclinical Models to Dissect the Crosstalk between Cancer Cells and the Tumor Microenvironment

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Three-Dimensional Tumor Models to Study Cancer Stemness-Mediated Drug Resistance

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Bioengineering toolkits for potentiating organoid therapeutics

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Synthetic Photoresponsive Hydrogels Enable In Situ Control Over Murine Intestinal Monolayer Differentiation and Crypt Formation

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Engineering the Future of Regenerative Medicines in Gut Health with Stem Cell-Derived Intestinal Organoids

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Guiding tissue-scale self-organization

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Gut Microbiota in Colorectal Cancer: Associations, Mechanisms, and Clinical Approaches

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Modelling adult stem cells and their niche in health and disease with epithelial organoids

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Organoid-based in vitro system and reporter for the study of Cryptosporidium parvum sexual reproduction

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Establishment of a Modular Anaerobic Human Intestine Chip

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Exploring Toxoplasma gondii´s Biology within the Intestinal Epithelium: intestinal-derived models to unravel sexual differentiation

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Work smart, not hard: How array tomography can help increase the ultrastructure data output

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Deciphering the Tumor Microenvironment of Colorectal Cancer and Guiding Clinical Treatment With Patient-Derived Organoid Technology: Progress and Challenges

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A novel membrane-on-chip guides morphogenesis for the reconstruction of the intestinal crypt-villus axis

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Facile photopatterning of perfusable microchannels in hydrogels for microphysiological systems

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Fibroblasts modulate epithelial cell behavior within the proliferative niche and differentiated cell zone within a human colonic crypt model

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Emerging biofabrication approaches for gastrointestinal organoids towards patient specific cancer models

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The mechanical forces that shape our senses

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Recent advances in biofabricated gut models to understand the gut-brain axis in neurological diseases

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Advancing intestinal organoid technology to decipher nano-intestine interactions and treat intestinal disease

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Application of colloidal photonic crystals in study of organoids

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A Microfluidics Approach for the Functional Investigation of Signaling Oscillations Governing Somitogenesis

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Bioengineered Microphysiological Placental Models: Towards Improving Understanding of Pregnancy Health and Disease

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Leveraging microphysiological systems to expedite understanding of host–parasite interactions

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Advancing intestinal disease research using gut-on-a-chip

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Three-dimensional bioprinting of in vitro tumor organoid and organ-on-a-chip models

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Research Models to Mimic Necrotizing Enterocolitis and Inflammatory Bowel Diseases: Focus on Extracellular Vesicles Action

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Utilization of intestinal organoid models for assessment of micro/nano plastic-induced toxicity

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Structural materials meet synthetic biology in biomedical applications

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Bridging systems biology and tissue engineering: Unleashing the full potential of complex 3D in vitro tissue models of disease

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Peiminine ameliorates Crohn’s disease-like colitis by enhancing the function of the intestinal epithelial barrier through Nrf2/HO1 signal

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Recent advances in cell-based in vitro models for predicting drug permeability across brain, intestinal, and pulmonary barriers

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Bioengineered human gut-on-a-chip for advancing non-clinical pharmaco-toxicology

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Understanding neurotropic enteric viruses: routes of infection and mechanisms of attenuation

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Organ‐on‐Chip: The Future of Nutrition Research in a One Health World

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Dissecting Exosomal–Tumoral–Vascular Interactions of Single Tumor Cells and Clusters Using a Tumoral-Transendothelial Migration Chip

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The importance of intermediate filaments in the shape maintenance of myoblast model tissues

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A vascularized crypt-patterned colon model for high-throughput drug screening and disease modelling

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An Individual Patient's “Body” on Chips—How Organismoid Theory Can Translate Into Your Personal Precision Therapy Approach

Marx, U., Accastelli, E., David, R. M., Erfurth, H., Koenig, L., Lauster, R., Ramme, A. P., Reinke, P., Volk, H., Winter, A., et al. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.728866 · Cited by 15

An extracellular matrix niche secreted by epithelial cells drives intestinal organoid formation

Chrisnandy, A., & Lütolf, M. P. (2025) · Developmental Cell · doi:10.1016/j.devcel.2025.06.026 · Cited by 11

Engineering biomimetic tissue barrier models on chips: From design and fabrication to applications in disease modeling and drug screening

Nasiri, R., Madadelahi, M., Nikmaneshi, M. R., Gökçe, B., Bijarchi, M. A., Shah, S., Tirpáková, Z., Gastel, D. V., Taebnia, N., de Barros, N. R., et al. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123739 · Cited by 14

Organoids in respiratory virus research: advances and perspectives

Li, X., Xiao, H., Zhou, M., Yang, C., Yang, X., Cheng, T., Yuan, L., & Xia, N. (2025) · Molecular Biomedicine · doi:10.1186/s43556-025-00343-x · Cited by 11

Cardiac Organoids: A 3D Technology for Disease Modeling and Drug Screening

Zhu, Y., Yang, S., Zhang, T., Ge, Y., Wan, X., & Liang, G. (2023) · Current Medicinal Chemistry · doi:10.2174/0929867331666230727104911 · Cited by 11

3D sheep rumen epithelial structures driven from single cells in vitro

Xu, Z., Xu, X., Yang, B., Mi, Y., & Wang, J. (2023) · Veterinary Research · doi:10.1186/s13567-023-01234-1 · Cited by 11

Adult Bovine-Derived Small and Large Intestinal Organoids: In Vitro Development and Maintenance

Kawasaki, M., Dykstra, G. D., McConnel, C. S., Burbick, C. R., & Ambrosini, Y. M. (2023) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1155/2023/3095002 · Cited by 11

Hydrogel-Integrated Millifluidic Systems: Advancing the Fabrication of Mucus-Producing Human Intestinal Models

Almalla, A., Alzain, N., Elomaa, L., Richter, F., Scholz, J., Lindner, M., Siegmund, B., & Weinhart, M. (2024) · Cells · doi:10.3390/cells13131080 · Cited by 12

Construction of multilayered small intestine-like tissue by reproducing interstitial flow

Deguchi, S., Kosugi, K., Takeishi, N., Watanabe, Y., Morimoto, S., Negoro, R., Yokoi, F., Futatsusako, H., Nakajima‐Koyama, M., Iwasaki, M., et al. (2024) · Cell stem cell · doi:10.1016/j.stem.2024.06.012 · Cited by 11

Novel organoids mode evaluating the food nutrition and safety: Current state and future prospects

Tan, F., Cui, P., Li, S., Tan, Y., & Ma, A. (2024) · Food Frontiers · doi:10.1002/fft2.451 · Cited by 11

Fabrication Strategies for Bioinspired and Functional Lung‐on‐Chips

Doryab, A., Braig, J., Jüngst, T., Ryma, M., & Gröll, J. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202407725 · Cited by 12

Compressible Hollow Microlasers in Organoids for High-Throughput and Real-Time Mechanical Screening

Fang, G., Ho, B. X., Xu, H., Gong, C., Qiao, Z., Liao, Y., Zhu, S., Lu, H., Nie, N., Zhou, T., et al. (2024) · ACS Nano · doi:10.1021/acsnano.4c08886 · Cited by 12

Bioengineering microfluidic organoids-on-a-chipPreprint

Nikolaev, M., Mitrofanova, O., Broguière, N., Geraldo, S., Tabata, Y., Brandenberg, N., Gjorevski, N., & Lütolf, M. P. (2020) · doi:10.21203/rs.3.pex-903/v1 · Cited by 3

Bioengineering human mini-intestines with in vivo-like complexity and function

Mitrofanova, O. (2023) · Infoscience (Ecole Polytechnique Fédérale de Lausanne) · doi:10.5075/epfl-thesis-10047

Intestinal epithelial organoids fuse to form self-organizing tubes in floating collagen gels

Sachs, N., Tsukamoto, Y., Kujala, P., Peters, P. J., & Clevers, H. C. (2017) · Development · doi:10.1242/dev.143933 · Cited by 144

Bioengineering of morphologically and functionally accurate in vitro intestinal models

Langer, J. (2025) · Infoscience (Ecole Polytechnique Fédérale de Lausanne) · doi:10.5075/epfl-thesis-10932

Next-generation intestinal organoids

Ray, K. (2020) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-020-00371-8 · Cited by 10