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Cited by 1,002

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Measurement of SARS-CoV-2 RNA in wastewater tracks community infection dynamics

Open access
Peccia, Jordan, Zulli, Alessandro, Brackney, Doug E., Grubaugh, Nathan D., Kaplan, Edward H., Casanovas-Massana, Arnau, Ko, Albert I., Malik, Amyn A., Wang, Dennis, Wang, Mike, Warren, Joshua L., Weinberger, Daniel M., Arnold, Wyatt, Omer, Saad B.·2020·Nature Biotechnology

Abstract

We measured severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA concentrations in primary sewage sludge in the New Haven, Connecticut, USA, metropolitan area during the Coronavirus Disease 2019 (COVID-19) outbreak in Spring 2020. SARS-CoV-2 RNA was detected throughout the more than 10-week study and, when adjusted for time lags, tracked the rise and fall of cases seen in SARS-CoV-2 clinical test results and local COVID-19 hospital admissions. Relative to these indicators, SARS-CoV-2 RNA concentrations in sludge were 0–2 d ahead of SARS-CoV-2 positive test results by date of specimen collection, 0–2 d ahead of the percentage of positive tests by date of specimen collection, 1–4 d ahead of local hospital admissions and 6–8 d ahead of SARS-CoV-2 positive test results by reporting date. Our data show the utility of viral RNA monitoring in municipal wastewater for SARS-CoV-2 infection surveillance at a population-wide level. In communities facing a delay between specimen collection and the reporting of test results, immediate wastewater results can provide considerable advance notice of infection dynamics. Testing sewage for the novel coronavirus reveals epidemiological trends.

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Metadata

Authors
Peccia, J., Zulli, A., Brackney, D. E., Grubaugh, N. D., Kaplan, E. H., Casanovas-Massana, A., Ko, A. I., Malik, A. A., Wang, D., Wang, M., Warren, J. L., Weinberger, D. M., Arnold, W., & Omer, S. B.
Venue
Nature Biotechnology
Published
2020-09-18
Volume
38
Issue
10
Pages
1164-1167
ISSN
  • 0733-222X (ISSN-L)
  • 1087-0156
  • 1546-1696
OpenAlex
W3087611057
Cited by
1,002
References
3
FWCI
20.97
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Measurement of SARS-CoV-2 RNA in wastewater tracks community infection dynamics. https://app.cochat.ai/papers/10.1038/s41587-020-0684-z
The paper
Peccia, J., Zulli, A., Brackney, D. E., Grubaugh, N. D., Kaplan, E. H., Casanovas-Massana, A., Ko, A. I., Malik, A. A., Wang, D., Wang, M., Warren, J. L., Weinberger, D. M., Arnold, W., & Omer, S. B. (2020). Measurement of SARS-CoV-2 RNA in wastewater tracks community infection dynamics. Nature Biotechnology. https://doi.org/10.1038/s41587-020-0684-z

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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