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The RNA m6A landscape during human oocyte-to-embryo transition

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The catalytic efficiency of METTL16 affects cellular processes by governing the intracellular S-adenosylmethionine setpoint

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Crosstalk between m6A and coding/non-coding RNA in cancer and detection methods of m6A modification residues

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Epitranscriptomic control of cancer immunity and therapy resistance

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Nanopore direct RNA sequencing and the epitranscriptome: Advances in mapping native RNA landscapes

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Exploring N6-methyladenosine (m6A) modification in tree species: opportunities and challenges

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The role of m6A methylation in targeted therapy resistance in lung cancer

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The pseudorabies virus UL13 protein kinase triggers phosphorylation of the RNA demethylase FTO, which is associated with FTO-dependent suppression of interferon-stimulated gene expression

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Epigenetic regulation in female reproduction: the impact of m6A on maternal-fetal health

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m6A modification regulates cell proliferation via reprogramming the balance between glycolysis and pentose phosphate pathway

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The Transcriptome-Wide Mapping of 2-Methylthio-N6-isopentenyladenosine at Single-Base Resolution

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Allele-specific RNAN6-methyladenosine modifications reveal functional genetic variants in human tissuesPreprint

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Challenges to mapping and defining m 6 A function in viral RNA

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A review of advances in analytical strategies for RNA methylation

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Hypoxic stabilization of RIPOR3 mRNA via METTL3-mediated m6A methylation drives breast cancer progression and metastasis

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m6ATM: a deep learning framework for demystifying the m6A epitranscriptome with Nanopore long-read RNA-seq data

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A Quantitative Sequencing Method for 5‐Formylcytosine in RNA

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Ascorbic Acid Reprograms Epigenome and Epitranscriptome by Reducing Fe(III) in the Catalytic Cycle of Dioxygenases

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The metabolic baton: conducting the dance of N6-methyladenosine writing and erasing

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Refining the role of N6-methyladenosine in cancer

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AI techniques have facilitated the understanding of epitranscriptome distribution

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Loss of YTHDC1 m6A reading function promotes invasiveness in urothelial carcinoma of the bladder

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Directing RNA-modifying machineries towards endogenous RNAs: opportunities and challenges.

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txtools: an R package facilitating analysis of RNA modifications, structures, and interactions

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Chemical and Enzyme‐Mediated Chemical Reactions for Studying Nucleic Acids and Their Modifications

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Quantitative mapping of the mammalian epitranscriptome

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m6A modification: a new avenue for anti-cancer therapy

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Reinvestigating the clinical relevance of the m6A writer METTL3 in urothelial carcinoma of the bladder

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Strategies for RNA m6A modification application in crop improvement

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RNA Modification in Metabolism

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Decoding m6Am by simultaneous transcription-start mapping and methylation quantification

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Exploring Site-Specific N6-Methyladenosine Modifications as New Cancer Biomarkers via SERS-Based Single-Cell Assay and Histopathological Imaging

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Unraveling brain complexity: from single-cell to spatial m6A technologies

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Meta-unstable mRNAs in activated CD8+ T cells are defined by interlinked AU-rich elements and m6A mRNA methylation

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Recent advances in the interplay between stress granules and m6A RNA modification

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Decoding N6-methyladenosine’s dynamic role in stem cell fate and early embryo development: insights into RNA–chromatin interactions

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m6A modification is incorporated into bacterial mRNA without specific functional benefit

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Understanding the Epitranscriptome for Avant-Garde Brain Tumour Diagnostics

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Interplay between N-adenosine RNA methylation and mRNA splicing

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An experimental workflow for identifying RNA m6A alterations in cellular senescence by methylated RNA immunoprecipitation sequencing

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Spatially Resolved Multibait Mapping of Stress Granule and Processing Body Transcriptome

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ALKBH5 in development: decoding the multifaceted roles of m6A demethylation in biological processes

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Regulatory roles of RNA modifications in plant development and fruit ripening

Li, T., Huang, J., Wang, G., Li, H., & Lü, P. (2025) · aBIOTECH · doi:10.1007/s42994-025-00240-5 · Cited by 7

Epitranscriptomic modifications in embryonic development: insights into natural and ART-induced mechanisms and implications

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Complexoform-restricted covalent TRMT112 ligands that allosterically agonize METTL5

Goetzke, F. W., Bernard, S. M., Ju, C., Pollock, J., DeMeester, K. E., Gross, J., Simon, G. M., He, C., Melillo, B. N., & Cravatt, B. F. (2026) · Nature Chemical Biology · doi:10.1038/s41589-025-02099-5 · Cited by 8

Comprehensive mapping of RNA modification dynamics and crosstalk via deep learning and nanopore direct RNA-sequencing

Dong, H., Gao, Y., Cai, Z., Li, Y., Li, X., Zhao, F., & Zhang, J. (2026) · Nature Communications · doi:10.1038/s41467-026-68419-y · Cited by 7

m6A RNA Methylation in Plants: From Molecular Insights to Applications

Song, P., Cai, Z., & Jia, G. (2026) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-070225-033859 · Cited by 7

DNA-Compatible Benzotriazinone Formation through Aryl Diazonium Intermediates

Liu, C., Li, X., Zhang, J., Li, Y., Zhang, G., & Li, Y. (2023) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.2c02686 · Cited by 7

Decoding epitranscriptomic regulation of viral infection: mapping of RNA N6-methyladenosine by advanced sequencing technologies

Fan, X., Zhang, Y., Guo, R., Yue, K., Smagghe, G. J., Lu, Y., & Wang, L. (2024) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-024-00564-y · Cited by 7

RNA methylation: A new promising biomaker in cancer liquid biopsy

Xu, C., Xu, X., Huang, Y., Shang, S., & Ma, L. (2025) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2025.189337 · Cited by 7

Disease Diagnosis Based on Nucleic Acid Modifications

Xue, X., Wang, Z., Wang, Y., & Zhou, X. (2023) · ACS Chemical Biology · doi:10.1021/acschembio.3c00251 · Cited by 7

SCARPET: site-specific quantification of methylated and nonmethylated adenosines reveals m6A stoichiometry

Mirza, A. H., Bram, Y., Schwartz, R. E., & Jaffrey, S. R. (2023) · RNA · doi:10.1261/rna.079776.123 · Cited by 7

Passive shaping of intra- and intercellular m6A dynamics via mRNA metabolismPreprint

Dierks, D., Shachar, R., Nir, R., García-Campos, M. A., Uzonyi, A., Wiener, D., Toth, U., Rossmanith, W., Lasman, L., Slobodin, B., et al. (2024) · eLife · doi:10.7554/elife.100448 · Cited by 7

N6-methyladenosine and intervertebral disc degeneration: Advances in detection and pathological insights

Liu, B., Song, G., Wang, Y., Song, C., Cao, Y., Tong, J., Wang, Y., Fan, X., Shi, N., Zhao, H., et al. (2025) · Journal of Orthopaedic Translation · doi:10.1016/j.jot.2025.05.004 · Cited by 6

m6AConquer: a consistently quantified and orthogonally validated database for the N 6-methyladenosine (m6A) epitranscriptome

Zhao, X., Ye, H., He, D., Liu, H., Li, T., Rigden, D. J., & Wei, Z. C. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf1204 · Cited by 6

Mitochondria at the intersections of RNA modifications and metabolism reprogramming implications in cell death, tumor microenvironment, and immunotherapy

Zhang, J., Zhang, H., Chen, L., Wu, Y., Xie, J., Yang, Y., Chen, A., Shahatiaili, A., Muhammad, S., Yang, W., et al. (2025) · Journal of Hematology & Oncology · doi:10.1186/s13045-025-01762-7 · Cited by 7

Advances in Quantitative Techniques for Mapping RNA Modifications

Tian, L., Vallabhaneni, B., & Chang, Y. (2025) · Life · doi:10.3390/life15121888 · Cited by 6

Advances in mapping analysis of ribonucleic acid modifications through sequencing

Xiong, J., Feng, T., & Yuan, B. (2024) · Chinese Journal of Chromatography · doi:10.3724/sp.j.1123.2023.12025 · Cited by 6

N6-methyladenosine and its epitranscriptomic effects on hematopoietic stem cell regulation and leukemogenesis

Chang, K.-J., Shiau, L.-Y., Lin, S.-C., Cheong, H.-P., Wang, C., Ma, C., Liang, Y., Yang, Y., Ko, P., Hsu, C.-H., et al. (2024) · Molecular Medicine · doi:10.1186/s10020-024-00965-x · Cited by 6

High‐throughput detection of RNA modifications at single base resolution

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Heterogeneity of chemical modifications on RNA

Goh, W. S. S., & Kuang, Y. (2023) · Biophysical Reviews · doi:10.1007/s12551-023-01128-8 · Cited by 6

Decoding m6Am by simultaneous transcription-start mapping and methylation quantificationPreprint

Liu, J. F., Hawley, B. R., Nicholson, L. S., & Jaffrey, S. R. (2024) · eLife · doi:10.7554/elife.104139 · Cited by 6

Epi-transcriptome analysis reveals the lack of N-methyladenosine modifications in two RNA viruses infecting watermelon

Pan, F., Jing, J., Qiu, Y., Li, M., Zhou, X., & Li, S. (2025) · 中国科学通报：英文版 · doi:10.1016/j.scib.2025.07.019 · Cited by 5

Molecular mechanisms and crop improvement potential of RNA N6-methyladenosine in plants

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Quantitative CRACI reveals transcriptome-wide distribution of RNA dihydrouridine at base resolution

Ju, C., Li, H., Jiang, B., Zhu, X., Liang, C., Han, Z., Zou, J., Liu, Y., Shen, S., Shah, H., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-63918-w · Cited by 5

Multi-region m6A epitranscriptome profiling of the human brain reveals spatial and temporal variation and enrichment of disease-associated loci

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Comprehensive discovery of m6A sites in the human transcriptome at single-molecule resolution

Kang, G., Hwang, H., Jeon, H., Choi, H., Chang, H. R., Yeo, N., Park, J., Son, N., Jeon, E., Lim, J., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-67417-w · Cited by 5

FOCAS: Transcriptome-wide screening of individual m6A sites functionally dissects epitranscriptomic control of gene expression in cancer

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Integrative analysis of nanopore direct RNA sequencing data reveals a global impact of pseudouridylation on m6A and m5C modifications

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