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The HDAC7–TET2 epigenetic axis is essential during early B lymphocyte development

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Advances in molecular characterization of myeloid proliferations associated with Down syndrome

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MIR retrotransposons link the epigenome and the transcriptome of coding genes in acute myeloid leukemia

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Preleukemic single-cell landscapes reveal mutation-specific mechanisms and gene programs predictive of AML patient outcomes

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Cell of origin epigenetic priming determines susceptibility to Tet2 mutation

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Quantifying Landscape‐Flux via Single‐Cell Transcriptomics Uncovers the Underlying Mechanism of Cell Cycle

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Epigenomic technologies for precision oncology

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CpG island methylator phenotype classification improves risk assessment in pediatric T-cell acute lymphoblastic leukemia

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A pilot clinical trial of oral tetrahydrouridine/decitabine for noncytotoxic epigenetic therapy of chemoresistant lymphoid malignancies

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DNMT3A and TET2 mutations reshape hematopoiesis in opposing ways

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Exposure to microbial products followed by loss of Tet2 promotes myelodysplastic syndrome via remodeling HSCs

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HDAC6 deacetylates IDH1 to promote the homeostasis of hematopoietic stem and progenitor cells

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Persistent postremission clonal hematopoiesis shapes the relapse trajectories of acute myeloid leukemia

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TET2 deficiency increases the competitive advantage of hematopoietic stem and progenitor cells through upregulation of thrombopoietin receptor signaling

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DNA methylation safeguards the generation of hematopoietic stem and progenitor cells by repression of Notch signaling

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Drug Repurposing by Tumor Tissue Editing

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Selective advantage of mutant stem cells in clonal hematopoiesis occurs by attenuating the deleterious effects of inflammation and agingPreprint

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Hematopoietic differentiation persists in human iPSCs defective in de novo DNA methylation

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Identifying ADGRG1 as a specific marker for tumor-reactive T cells in acute myeloid leukemia

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Clonal hematopoiesis landscape in frequent blood donors

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Increasing Complexity of Molecular Landscapes in Human Hematopoietic Stem and Progenitor Cells during Development and Aging

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Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylationPreprint

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Emerging DNA Methylome Targets in FLT3-ITD-Positive Acute Myeloid Leukemia: Combination Therapy with Clinically Approved FLT3 Inhibitors

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Epigenetic aspects of DC development and differentiation

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Molecular Landscapes and Models of Acute Erythroleukemia

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DNA Methylation Reflects Cis‐Genetic Differentiation Across the European Crow Hybrid Zone

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Cross-tissue patterns of DNA hypomethylation reveal genetically distinct histories of cell development

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Single cell genotypic and phenotypic analysis of measurable residual disease in acute myeloid leukemiaPreprint

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Molecular Plasticity Results in Oncofetal Reprogramming and Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia

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Shining light on dark selection in healthy human tissues

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Deciphering the regulatory landscape of murine splenic response to anemic stress at single-cell resolution

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Inclusion of temporal information in single cell transcriptomics

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Why Single-Cell Sequencing Has Promise in MDS

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Hematopoietic regeneration under the spell of epigenetic-epitranscriptomic factors and transposable elements

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A multiomics approach reveals RNA dynamics promote cellular sensitivity to DNA hypomethylation

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Ontogeny and transcriptional regulation of Thetis cells

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Epigenetic alterations in AML: Deregulated functions leading to new therapeutic options

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Predicting which subsets of patients with myelodysplastic neoplasms are more likely to progress to overt chronic myelomonocytic leukemia

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Biological insights into the role of TET2 in T cell lymphomas

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Clonal hematopoiesis of indeterminate potential (CHIP): A potential contributor to lymphoma

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Epigenetic modifiers in normal and aberrent erythropoeisis

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Cell-intrinsic factors governing quiescence vis-à-vis activation of adult hematopoietic stem cells

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NSD1 in erythroid differentiation and leukemogenesis

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TET2 in epigenetic control of immune cells: Implications for inflammatory responses and age-related pathologies

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Lineage tracing from cellular heritage to disease destiny

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Trained immunity links hematopoietic stem cell aging to aging-associated inflammation

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The molecular profile in patients with polycythemia vera and essential thrombocythemia is dynamic and correlates with disease’s phenotype

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The systemic costs of hematopoietic stem cell aging

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Clonal hematopoiesis in cardiovascular aging: Insights from the verona heart study

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Hematopoiesis of Indeterminate Potential and Atherothrombotic Risk

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Somatic Dnmt3a inactivation leads to slow, canonical DNA methylation loss in murine hematopoietic cells

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Frequent whole blood donations select for DNMT3A variants mediating enhanced response to erythropoietinPreprint

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TP53 clonal hematopoiesis promotes atherosclerosis

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ASXL1 deficiency causes epigenetic dysfunction, combined immunodeficiency, and EBV-associated lymphoma

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Aberrant splicing of MBD1 reshapes the epigenome to drive convergent myeloerythroid defects in MDS

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The Evolution of Polyclonal Competition in Aging Hematopoiesis

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A single-cell lens into the co-evolution of genotypes and phenotypes in cancer

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