Cited by 305Reproductive tract infections researchGut microbiota and healthOral microbiology and periodontitis research

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Racioethnic diversity in the dynamics of the vaginal microbiome during pregnancy

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Serrano, Myrna G., Parikh, Hardik I., Brooks, J. Paul, Edwards, David J., Arodz, Tom J., Edupuganti, Laahirie, Huang, Bernice, Girerd, Philippe H., Bokhari, Yahya A., Bradley, Steven P., Brooks, Jamie L., Dickinson, Molly R., Drake, Jennifer I., Duckworth, Robert A., Fong, Stephen S., Glascock, Abigail L., Jean, Sophonie, Jimenez, Nicole R., Khoury, Joseph, Koparde, Vishal N., Lara, Ana M., Lee, Vladimir, Matveyev, Andrey V., Milton, Sarah H., Mistry, Shreni D., Rozycki, Sarah K., Sheth, Nihar U., Smirnova, Ekaterina, Vivadelli, Stephany C., Wijesooriya, N. Romesh, Xu, Jie, Xu, Ping, Chaffin, Donald O., Sexton, Amber L., Gravett, Michael G., Rubens, Craig E., Hendricks-Muñoz, Karen D., Jefferson, Kimberly K., Strauss, Jerome F., Fettweis, Jennifer M., Buck, Gregory A.·2019·Nature Medicine

DOI 10.1038/s41591-019-0465-8PMC PMC6746180

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Abstract

The microbiome of the female reproductive tract has implications for women's reproductive health. We examined the vaginal microbiome in two cohorts of women who experienced normal term births: a cross-sectionally sampled cohort of 613 pregnant and 1,969 non-pregnant women, focusing on 300 pregnant and 300 non-pregnant women of African, Hispanic or European ancestry case-matched for race, gestational age and household income; and a longitudinally sampled cohort of 90 pregnant women of African or non-African ancestry. In these women, the vaginal microbiome shifted during pregnancy toward Lactobacillus-dominated profiles at the expense of taxa often associated with vaginal dysbiosis. The shifts occurred early in pregnancy, followed predictable patterns, were associated with simplification of the metabolic capacity of the microbiome and were significant only in women of African or Hispanic ancestry. Both genomic and environmental factors are likely contributors to these trends, with socioeconomic status as a likely environmental influence.

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Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
Benjamini, Y., & Hochberg, Y. (1995) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1995.tb02031.x · Cited by 109,482
Fitting Linear Mixed-Effects Models Using lme4
Bates, D., Mächler, M., Bolker, B., & Walker, S. (2015) · Journal of Statistical Software · doi:10.18637/jss.v067.i01 · Cited by 86,835
Trimmomatic: a flexible trimmer for Illumina sequence data
Bolger, A. M., Lohse, M., & Usadel, B. (2014) · Bioinformatics · doi:10.1093/bioinformatics/btu170 · Cited by 65,548
Fast and accurate short read alignment with Burrows-Wheeler transform
Li, H., & Durbin, R. (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp324 · Cited by 58,607
Fast and accurate long-read alignment with Burrows-Wheeler transform.
Li, H., & Durbin, R. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btp698 · Cited by 12,063
Vaginal microbiome of reproductive-age women
Ravel, J., Gajer, P., Abdo, Z., Schneider, G. M., Koenig, S. S. K., McCulle, S. L., Karlebach, S., Gorle, R., Russell, J., Tacket, C. O., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1002611107 · Cited by 4,254
Controlling the false discovery rate in behavior genetics research
Benjamini, Y., Drai, D., Elmer, G., Kafkafi, N., & Golani, I. (2001) · Behavioural Brain Research · doi:10.1016/s0166-4328(01)00297-2 · Cited by 4,146
The worldwide incidence of preterm birth: a systematic review of maternal mortality and morbidity
Beck, S., WOJDYLA, D. M., Say, L., Betrán, A. P., Meraldi, M., Requejo, J. H., Rubens, C. E., Menon, R., & Look, P. V. (2009) · Bulletin of the World Health Organization · doi:10.2471/blt.08.062554 · Cited by 2,190
Self-citation
The NIH Human Microbiome ProjectPreprint
The NIH HMP Working Group, Peterson, J. L., Garges, S., Giovanni, M. Y., McInnes, P., Wang, L., Schloss, J. A., Bonazzi, V. R., McEwen, J. E., Wetterstrand, K. A., et al. (2009) · Genome Research · doi:10.1101/gr.096651.109 · Cited by 2,168
Metagenomic microbial community profiling using unique clade-specific marker genes
Segata, N., Waldron, L., Ballarini, A., Narasimhan, V., Jousson, O., & Huttenhower, C. (2012) · Nature Methods · doi:10.1038/nmeth.2066 · Cited by 1,776

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Strout, N., Pasic, L., Hicks, C., Chua, X., Tashvighi, N., Butler, P., Liu, Z., El‐Assaad, F., Holmes, E. C., Susic, D. F., et al. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20186736 · Cited by 4
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Cervicovaginal microbiome in twin vs singleton gestations
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Liu, Z., Yu, W., Sun, T., Li, M., Li, X., Qin, L., Liu, X., Bian, Y., Zhao, S., Zhao, Q., et al. (2025) · Microbiome · doi:10.1186/s40168-025-02212-9 · Cited by 1
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Ruiz‐Ruiz, S., Piquer-Esteban, S., Pérez-Rocher, B., Pérez‐Brocal, V., Arnau, V., Artacho, A., Diaz, W., Jiménez‐Hernández, N., Pons, J., Castro, J. A., et al. (2026) · Scientific Reports · doi:10.1038/s41598-026-35033-3 · Cited by 1
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Liu, X., Tang, W., Li, C., Jiao, Y., Bai, Y., Xiang, L., & Wu, Z. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1770446 · Cited by 2
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Banchi, P., Mila, H., Selma‐Royo, M., Tal, S., Péron, F., & Gaillard, V. (2026) · Frontiers in Veterinary Science · doi:10.3389/fvets.2026.1817504 · Cited by 1
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Wright, M. L. (2020) · Journal of Women s Health · doi:10.1089/jwh.2020.8394 · Cited by 1
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Halani, P. K., Gelman, E., Duchein, Y., Roselli, N., & Leegant, A. (2021) · Urogynecology · doi:10.1097/spv.0000000000001085 · Cited by 1
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Beliaeva, N. R., Budilovskaya, O. V., Khusnutdinova, T. А., Krysanova, A. А., Shalepo, K. V., Savicheva, A. M., & Tapilskaya, N. I. (2023) · Journal of obstetrics and women s diseases · doi:10.17816/jowd585649 · Cited by 1
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Kendle, A. M., Buhimschi, C. S., & Lockwood, C. J. (2023) · Wiley eBooks · doi:10.1002/9781119636540.ch40 · Cited by 1
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Li, D., Tian, S., Zhu, W. Y., Su, Y., Wang, T., Ma, T., Mishra, S. K., Shi, L., Wei, R., Xu, Z., et al. (2020) · doi:10.21203/rs.2.23607/v2
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Rahnavard, A., Chatterjee, R., Wen, H., Gaylord, C. K., Mugusi, S. F., Klatt, K. C., & Smith, E. R. (2022) · Research Square · doi:10.21203/rs.3.rs-2214567/v1
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Additional file 2 of Composition of the vaginal microbiota during pregnancy in women living in sub-Saharan Africa: a PRISMA-compliant review
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Authors: Serrano, M. G., Parikh, H. I., Brooks, J. P., Edwards, D. J., Arodz, T. J., Edupuganti, L., Huang, B., Girerd, P. H., Bokhari, Y. A., Bradley, S. P., Brooks, J. L., Dickinson, M. R., Drake, J. I., Duckworth, R. A., Fong, S. S., Glascock, A. L., Jean, S., Jimenez, N. R., Khoury, J., Koparde, V. N., Lara, A. M., Lee, V., Matveyev, A. V., Milton, S. H., Mistry, S. D., Rozycki, S. K., Sheth, N. U., Smirnova, E., Vivadelli, S. C., Wijesooriya, N. R., Xu, J., Xu, P., Chaffin, D. O., Sexton, A. L., Gravett, M. G., Rubens, C. E., Hendricks-Muñoz, K. D., Jefferson, K. K., Strauss, J. F., Fettweis, J. M., & Buck, G. A.
Affiliations: Virginia Commonwealth University (US)
Global Alliance to Prevent Prematurity and Stillbirth (US)
University of Washington (US)
Corresponding author: Buck, Gregory A.
ORCID: Serrano, Myrna G.
Parikh, Hardik I.
Brooks, J. Paul
Edwards, David J.
Arodz, Tom J.
Edupuganti, Laahirie
Bokhari, Yahya A.
Brooks, Jamie L.
Drake, Jennifer I.
Fong, Stephen S.
Glascock, Abigail L.
Jimenez, Nicole R.
Rozycki, Sarah K.
Smirnova, Ekaterina
Xu, Ping
Gravett, Michael G.
Jefferson, Kimberly K.
Strauss, Jerome F.
Fettweis, Jennifer M.
Buck, Gregory A.
Venue: Nature Medicine
Publisher: Springer Science and Business Media LLC
Published: 2019-05-29
Volume: 25
Issue: 6
Pages: 1001-1011
ISSN: 1078-8956 (ISSN-L)
1546-170X
DOI: 10.1038/s41591-019-0465-8
PMC: PMC6746180
OpenAlex: W2947787281
Cited by: 300
References: 70
Citations by year: 2026: 28 · 2025: 31 · 2024: 40 · 2023: 58 · 2022: 46 · 2021: 52 · 2020: 33 · 2019: 12
FWCI: 26.69
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.springernature.com/gp/researchers/text-and-data-mining (tdm)
www.springernature.com/gp/researchers/text-and-data-mining (vor)
Locations: Nature Medicine (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of General Medical Sciences (R25GM090084)
National Institute of Allergy and Infectious Diseases (UH2AI083263, UH3AI083263)
National Institute of Dental and Craniofacial Research (U54DE023786)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (U54HD080784, R01HD092415, R21HD092965)
Topics: Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
Keywords: vaginal microbiota, pregnancy, racial and ethnic diversity, Lactobacillus, vaginal dysbiosis, African ancestry, Hispanic origin, socioeconomic status, reproductive tract microbiome, term birth
MeSH terms: Host Microbial Interactions, Adult, Black or African American, Cross-Sectional Studies, Female, Hispanic or Latino, Humans, Pregnancy, Social Class, Vagina, Cohort Studies, White People, Biodiversity, Microbiota

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Racioethnic diversity in the dynamics of the vaginal microbiome during pregnancy

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