Cited by 2,270Infection Control and VentilationRespiratory viral infections researchSARS-CoV-2 and COVID-19 Research

The DOI matches its Crossref record; 47 of the 48 references it cites were found in a registry or an index.

Respiratory virus shedding in exhaled breath and efficacy of face masks

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Abstract

We identified seasonal human coronaviruses, influenza viruses and rhinoviruses in exhaled breath and coughs of children and adults with acute respiratory illness. Surgical face masks significantly reduced detection of influenza virus RNA in respiratory droplets and coronavirus RNA in aerosols, with a trend toward reduced detection of coronavirus RNA in respiratory droplets. Our results indicate that surgical face masks could prevent transmission of human coronaviruses and influenza viruses from symptomatic individuals.

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Metadata

Authors
Leung, N. H. L., Chu, D. K. W., Shiu, E. Y. C., Chan, K.-H., McDevitt, J. J., Hau, B. J. P., Yen, H.-L., Li, Y., Ip, D. K. M., Peiris, J. S. M., Seto, W.-H., Leung, G. M., Milton, D. K., & Cowling, B. J.
Affiliations
  • University of Hong Kong (HK)
  • Harvard University (US)
  • Queen Mary Hospital (CN)
  • University of Maryland, College Park (US)
Corresponding author
Cowling, Benjamin J.
Venue
Nature Medicine
Published
2020-04-03
Volume
26
Issue
5
Pages
676-680
ISSN
  • 1078-8956 (ISSN-L)
  • 1546-170X
OpenAlex
W3014271510
Cited by
2,270
References
48
Citations by year
2026: 43 · 2025: 98 · 2024: 166 · 2023: 232 · 2022: 400 · 2021: 683 · 2020: 643
FWCI
276.42
Type
journal article
Language
en
Open access
Locations
  • Nature Medicine (publishedVersion)
  • Research Square (acceptedVersion, cc-by)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • University Grants Committee (T11–705/14N)
  • Food and Health Bureau
  • Centers for Disease Control and Prevention (U01IP000497, U01CI000446)
  • Health and Medical Research Fund (13120592)
  • National Institute of Allergy and Infectious Diseases (RC1AI086900)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Infection Control and Ventilation
  • Health Sciences › Medicine › Epidemiology › Respiratory viral infections research
  • Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
Keywords
exhaled breath, surgical masks, influenza virus, human coronaviruses, rhinovirus, respiratory droplets, aerosols, acute respiratory illness, virus transmission prevention, children and adults
MeSH terms
COVID-19, Aerosols, Humans, Masks, Orthomyxoviridae, Pneumonia, Viral, Respiratory Tract Infections, RNA, Viral, Virus Shedding, Coronavirus Infections, Exhalation, Pandemics

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