The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
In Situ Bioprinting of Autologous Skin Cells Accelerates Wound Healing of Extensive Excisional Full-Thickness Wounds
Open accessAbstract
The early treatment and rapid closure of acute or chronic wounds is essential for normal healing and prevention of hypertrophic scarring. The use of split thickness autografts is often limited by the availability of a suitable area of healthy donor skin to harvest. Cellular and non-cellular biological skin-equivalents are commonly used as an alternative treatment option for these patients, however these treatments usually involve multiple surgical procedures and associated with high costs of production and repeated wound treatment. Here we describe a novel design and a proof-of-concept validation of a mobile skin bioprinting system that provides rapid on-site management of extensive wounds. Integrated imaging technology facilitated the precise delivery of either autologous or allogeneic dermal fibroblasts and epidermal keratinocytes directly into an injured area, replicating the layered skin structure. Excisional wounds bioprinted with layered autologous dermal fibroblasts and epidermal keratinocytes in a hydrogel carrier showed rapid wound closure, reduced contraction and accelerated re-epithelialization. These regenerated tissues had a dermal structure and composition similar to healthy skin, with extensive collagen deposition arranged in large, organized fibers, extensive mature vascular formation and proliferating keratinocytes.
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Citations
Cites
3D bioprinting of tissues and organs
Murphy, S. V., & Atala, A. (2014) · Nature Biotechnology · doi:10.1038/nbt.2958 · Cited by 7,034
Self-citationUse of an acellular allograft dermal matrix (AlloDerm) in the management of full-thickness burns
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Artificial Dermis for Major Burns: A Multi-Center Randomized Clinical Trial
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Skin tissue generation by laser cell printing
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Cited by
Progress in 3D bioprinting technology for tissue/organ regenerative engineering
Matai, I., Kaur, G., Seyedsalehi, A., McClinton, A., & Laurencin, C. T. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2019.119536 · Cited by 1,156
Inkjet Bioprinting of Biomaterials
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Self-citationInnovative Treatment Strategies to Accelerate Wound Healing: Trajectory and Recent Advancements
Kolimi, P., Narala, S., Nyavanandi, D., Youssef, A. A. A., & Dudhipala, N. (2022) · Cells · doi:10.3390/cells11152439 · Cited by 585
Breakthrough treatments for accelerated wound healing
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Metadata
- Authors
- Albanna, M., Binder, K. W., Murphy, S. V., Kim, J., Qasem, S. A., Zhao, W., Tan, J., El-Amin, I. B., Dice, D. D., Marco, J., Green, J., Xu, T., Skardal, A., Holmes, J. H., Jackson, J. D., Atala, A., & Yoo, J. J.
- Venue
- Scientific Reports
- Published
- 2019-02-12
- Volume
- 9
- Issue
- 1
- Pages
- 1856-1856
- ISSN
- 2045-2322 (ISSN-L)
- OpenAlex
- W2912301972
- Cited by
- 512
- References
- 28
- FWCI
- 36.41
- Type
- journal article
- Language
- en
- Open access
- gold
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- CoChat. (2026). Citation check: In Situ Bioprinting of Autologous Skin Cells Accelerates Wound Healing of Extensive Excisional Full-Thickness Wounds. https://app.cochat.ai/papers/10.1038/s41598-018-38366-w
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- Albanna, M., Binder, K. W., Murphy, S. V., Kim, J., Qasem, S. A., Zhao, W., Tan, J., El-Amin, I. B., Dice, D. D., Marco, J., Green, J., Xu, T., Skardal, A., Holmes, J. H., Jackson, J. D., Atala, A., & Yoo, J. J. (2019). In Situ Bioprinting of Autologous Skin Cells Accelerates Wound Healing of Extensive Excisional Full-Thickness Wounds. Scientific Reports. https://doi.org/10.1038/s41598-018-38366-w
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
