Cited by 3693D Printing in Biomedical ResearchHydrogels: synthesis, properties, applicationsTissue Engineering and Regenerative Medicine

Recent progress in extrusion 3D bioprinting of hydrogel biomaterials for tissue regeneration: a comprehensive review with focus on advanced fabrication techniques

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Askari, Mohsen, Afzali Naniz, Moqaddaseh, Kouhi, Monireh, Saberi, Azadeh, Zolfagharian, Ali, Bodaghi, Mahdi·2021·Biomaterials Science

Abstract

Over the last decade, 3D bioprinting has received immense attention from research communities to bridge the divergence between artificially engineered tissue constructs and native tissues.

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Crossref · 10.1039/d0bm00973c

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350 of 350 references verified0 citation errors · 0 not checkable

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  • Incorporation of PLCL with natural polysaccharides such as hyaluronic acid and chitosan improves hydrophilicity and cartilage regeneration ability of scaffolds.

    “the incorporation of PLCL with natural polysaccharides such as hyaluronic acid and chitosan can improve the hydrophilicity and cartilage regeneration ability of scaffolds [194]”

    From Application of PLCL as a biodegradable polymer in biomedical engineering (2026) · cites this paper as [194]

    The Cartilage section (page unavailable) reports enhanced cartilage tissue formation in PCL–alginate scaffolds containing TGFβ. That offers partial support for a synthetic-polymer/polysaccharide scaffold improving cartilage formation, but the review does not report the claimed PLCL combination with hyaluronic acid or chitosan, or an improvement in hydrophilicity (searched: PLCL, hyaluronic acid, chitosan, hydrophilicity). (LLM, conf=0.78)

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Research works printed but not linked: 11

  1. D. X. B. Chen, Extrusion Bioprinting of Scaffolds: An Introduction, in Extrus. Bioprinting Scaffolds Tissue Eng. Appl, Springer, Switzerland, 2019, pp. 1-13.
  2. D. X. B. Chen, Preparation of Scaffold Solutions and Characterization of Their Flow Behavior, in Extrus. Bioprinting Scaffolds Tissue Eng. Appl, 2019, pp. 91-114.
  3. D. X. B. Chen, Biomaterials for Bioprinting, in Extrus. Bioprinting Scaffolds Tissue Eng. Appl, Springer, Switzerland, 2019, pp. 33-48.
  4. L. Leng, S. Amini-Nik, Q. Ba, M. Jeschke and A. Guenther, Skin printer: Microfluidic approach for skin regeneration and wound dressings, in 17th Int. Conf. Miniaturized Systems Chem. Life Sci, 2013, pp. 1833-1835. 117
  5. A. De Mori, M. P. Fernández, G. Blunn, G. Tozzi and M. Roldo, 3D printing and electrospinning of composite hydrogels for cartilage and bone tissue engineering, Polymers, 2018, 10, 1-26, DOI: 10.3390/polym10030285. 169 · DOI
  6. J. Brian, C. H. Huang and A. A. Kyriacos, Cell-based tissue engineering startegies used in the clinical articular carti- lage, Biomaterials, 2016, 98, 1-22. 176
  7. M. Kesti, C. Eberhardt, G. Pagliccia, D. Kenkel, D. Grande, A. Boss and M. Zenobi-Wong, Bioprinting Complex Cartilaginous Structures with Clinically Compliant Biomaterials, Adv. Funct. Mater., 2015, 25, 7406-7417, DOI: 10.1002/adfm.201503423. 211 · DOI
  8. S. Wüst, R. Müller and S. Hofmann, 3D Bioprinting of complex channels-Effects of material, orientation, geo- metry, and cell embedding, J. Biomed. Mater. Res., Part A, 2015, 103, 2558-2570.
  9. G. J. Stewart, The Skeletal And Muscuar Systems, in Skelet. Muscuar Syst, Chelsea House, New York, 2009, pp. 10-14. 259
  10. G. J. Stewart, Muscles, Muscle Cells, and Muscle Tissues, in Skelet. Muscuar Syst, 2009, pp. 82-97. 260
  11. B. Yilmaz, A. Tahmasebifar and E. T. Baran, Bioprinting Technologies in Tissue Engineering, in Curr. Appl. Pharm. Biotechnol, Springer, Cham, 2019, pp. 279-319. 292

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Authors
Askari, M., Afzali Naniz, M., Kouhi, M., Saberi, A., Zolfagharian, A., & Bodaghi, M.
Affiliations
  • Amirkabir University of Technology (IR)
  • Department of Engineering
  • Isfahan University of Technology (IR)
  • Materials and Energy Research Center (IR)
  • Deakin University (AU)
  • Nottingham Trent University (GB)
Corresponding author
Bodaghi, Mahdi
Venue
Biomaterials Science
Published
2021
Volume
9
Issue
3
Pages
535-573
ISSN
  • 2047-4830 (ISSN-L)
  • 2047-4849
OpenAlex
W3092161699
Cited by
369
References
349
Citations by year
2026: 44 · 2025: 64 · 2024: 58 · 2023: 55 · 2022: 97 · 2021: 50 · 2020: 1
FWCI
4.24
Type
journal article
Language
en
Open access
Locations
  • Biomaterials Science (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Nottingham Trent University's Institutional Repository (Nottingham Trent Repository) (acceptedVersion)
  • Own your potential (DEAKIN) (submittedVersion)
  • Figshare (submittedVersion, cc-by)
Funders
  • Isfahan University of Medical Sciences
  • Isfahan University of Technology
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › 3D Printing in Biomedical Research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
  • Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
Keywords
hydrogel biomaterials, bioinks, tissue regeneration, tissue engineering scaffolds, skin scaffolds, bone scaffolds, cartilage scaffolds, vascular scaffolds, neural scaffolds, cardiac scaffolds, scaffold design
MeSH terms
Biocompatible Materials, Hydrogels, Tissue Engineering, Tissue Scaffolds, Bioprinting, Printing, Three-Dimensional

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