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VolcaNoseR is a web app for creating, exploring, labeling and sharing volcano plots

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Goedhart, Joachim, Luijsterburg, Martijn S.·2020·Scientific Reports

Abstract

Comparative genome- and proteome-wide screens yield large amounts of data. To efficiently present such datasets and to simplify the identification of hits, the results are often presented in a type of scatterplot known as a volcano plot, which shows a measure of effect size versus a measure of significance. The data points with the largest effect size and a statistical significance beyond a user-defined threshold are considered as hits. Such hits are usually annotated in the plot by a label with their name. Volcano plots can represent ten thousands of data points, of which typically only a handful is annotated. The information of data that is not annotated is hardly or not accessible. To simplify access to the data and enable its re-use, we have developed an open source and online web tool with R/Shiny. The web app is named VolcaNoseR and it can be used to create, explore, label and share volcano plots ( https://huygens.science.uva.nl/VolcaNoseR ). When the data is stored in an online data repository, the web app can retrieve that data together with user-defined settings to generate a customized, interactive volcano plot. Users can interact with the data, adjust the plot and share their modified plot together with the underlying data. Therefore, VolcaNoseR increases the transparency and re-use of large comparative genome- and proteome-wide datasets.

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Metadata

Authors
Goedhart, J., & Luijsterburg, M. S.
Venue
Scientific Reports
Published
2020-11-25
Volume
10
Issue
1
Pages
20560-20560
ISSN
2045-2322 (ISSN-L)
OpenAlex
W3109082402
Cited by
709
References
13
FWCI
17.98
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: VolcaNoseR is a web app for creating, exploring, labeling and sharing volcano plots. https://app.cochat.ai/papers/10.1038/s41598-020-76603-3
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Goedhart, J., & Luijsterburg, M. S. (2020). VolcaNoseR is a web app for creating, exploring, labeling and sharing volcano plots. Scientific Reports. https://doi.org/10.1038/s41598-020-76603-3

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