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Mitochondrial Functions in Infection and Immunity

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Master Regulator Analysis of the SARS-CoV-2/Human Interactome

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Network Analysis and Transcriptome Profiling Identify Autophagic and Mitochondrial Dysfunctions in SARS-CoV-2 Infection

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Organization of the human mitochondrial transcription initiation complex

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Network Analysis and Transcriptome Profiling Identify Autophagic and Mitochondrial Dysfunctions in SARS-CoV-2 InfectionPreprint

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RNA-GPS Predicts SARS-CoV-2 RNA Localization to Host Mitochondria and NucleolusPreprint

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Mitochondrial Functions in Infection and Immunity

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SARS-CoV-2, COVID-19 and the aging immune system

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Possible Pathogenesis and Prevention of Long COVID: SARS-CoV-2-Induced Mitochondrial Disorder

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The central role of mitochondrial fitness on antiviral defenses: An advocacy for physical activity during the COVID-19 pandemic

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Pathophysiological involvement of host mitochondria in SARS-CoV-2 infection that causes COVID-19: a comprehensive evidential insight

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NSP4 and ORF9b of SARS-CoV-2 Induce Pro-Inflammatory Mitochondrial DNA Release in Inner Membrane-Derived Vesicles

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Mechanisms of long COVID: An updated review

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Diabetes Mellitus, Energy Metabolism, and COVID-19

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SARS-CoV-2 mitochondrial metabolic and epigenomic reprogramming in COVID-19

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Immune system cells from COVID-19 patients display compromised mitochondrial-nuclear expression co-regulation and rewiring toward glycolysis

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ACE2-lentiviral transduction enables mouse SARS-CoV-2 infection and mapping of receptor interactions

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Mitochondrial oxidative stress, mitochondrial ROS storms in long COVID pathogenesis

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COVID‐19 metabolism: Mechanisms and therapeutic targets

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Targeted Down Regulation Of Core Mitochondrial Genes During SARS-CoV-2 InfectionPreprint

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Mitochondrial antioxidants abate SARS-COV-2 pathology in mice

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Mitochondrial Oxidative Phosphorylation in Viral Infections

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Myocardial Damage by SARS-CoV-2: Emerging Mechanisms and Therapies

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SARS-CoV-2 Achieves Immune Escape by Destroying Mitochondrial Quality: Comprehensive Analysis of the Cellular Landscapes of Lung and Blood Specimens From Patients With COVID-19

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The role of TRIM25 in the occurrence and development of cancers and inflammatory diseases

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Immunosenescence is a therapeutic target for frailty in older adults: a narrative review

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The Coronavirus Disease 2019 (COVID-19): Key Emphasis on Melatonin Safety and Therapeutic Efficacy

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Neurological Implications of COVID-19: Role of Redox Imbalance and Mitochondrial Dysfunction

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Metabolic Reprogramming in Respiratory Viral Infections: A Focus on SARS-CoV-2, Influenza, and Respiratory Syncytial Virus

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Nicotinamide pathways as the root cause of sepsis – an evolutionary perspective on macrophage energetic shifts

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Unraveling the role of the nucleocapsid protein in SARS-CoV-2 pathogenesis: From viral life cycle to vaccine development

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SUMO pathway, blood coagulation and oxidative stress in SARS-CoV-2 infection

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Viral mitochondriopathy in COVID-19

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Post infectious fatigue and circadian rhythm disruption in long-COVID and other infections: a need for further research

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COVID-19 and Mitochondrial Non-Coding RNAs: New Insights From Published Data

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Clinical effectiveness of medical ozone therapy in COVID-19

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Mitochondria in COVID-19: from cellular and molecular perspective

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Addressing the ‘hypoxia paradox’ in severe COVID-19: literature review and report of four cases treated with erythropoietin analogues

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Three-Dimensional Remodeling of SARS-CoV2-Infected Cells Revealed by Cryogenic Soft X-ray Tomography

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A mid‑pandemic night's dream: Melatonin, from harbinger of anti‑inflammation to mitochondrial savior in acute and long COVID‑19 (Review)

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Dynamic label-free analysis of SARS-CoV-2 infection reveals virus-induced subcellular remodeling

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Genome-Wide Association Study of COVID-19 Outcomes Reveals Novel Host Genetic Risk Loci in the Serbian Population

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Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila

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Gene Network Analysis of the Transcriptome Impact of SARS-CoV-2 Interacting MicroRNAs in COVID-19 Disease

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Putative role of mitochondria in SARS-CoV-2 mediated brain dysfunctions: a prospect

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Potential Beneficial Effects of Naringin and Naringenin on Long COVID—A Review of the Literature

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Proteomic landscape of SARS-CoV-2– and MERS-CoV–infected primary human renal epithelial cells

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The SARS-CoV-2 spike glycoprotein interacts with MAO-B and impairs mitochondrial energetics

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A Peek into Pandora’s Box: COVID-19 and Neurodegeneration

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Tuberculous Meningitis in Children: Treatment Outcomes at Discharge and Its Associated Factors in Eastern Ethiopia: A Five Years Retrospective Study

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Therapy of post-COVID-19 syndrome: improving the efficiency and safety of basic metabolic drug treatment with tiazotic acid (thiotriazoline)

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Human-derived air–liquid interface cultures decipher Alzheimer’s disease–SARS-CoV-2 crosstalk in the olfactory mucosa

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A Gene Cluster of Mitochondrial Complexes Contributes to the Cognitive Decline of COVID-19 Infection

Xu, W., An, X., Chen, M.-J., Ma, J., Wang, X.-Q., Yang, J.-N., Wang, Q., Wang, D., Wu, Y., Zeng, L., et al. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04471-3 · Cited by 8 · see citing works

SLIRP amplifies antiviral signaling via positive feedback regulation and contributes to autoimmune diseases

Ku, D., Yang, Y., Park, Y., Jang, D., Lee, N., Lee, Y.-K., Lee, K., Lee, J., Han, Y. B., Jang, S., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115588 · Cited by 9 · see citing works

SARS-CoV-2 induced liver injury: Incidence, risk factors, impact on COVID-19 severity and prognosis in different population groups

Liatsos, G. D. (2023) · World Journal of Gastroenterology · doi:10.3748/wjg.v29.i16.2397 · Cited by 9 · see citing works

Computers and preventative diagnosis. A survey with bioinformatics examples of mitochondrial small open reading frame peptides as portents of a new generation of powerful biomarkers

Robson, B. (2021) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2021.105116 · Cited by 9 · see citing works

A metabolic blueprint of COVID-19 and long-term vaccine efficacy

Berber, E., Sumbria, D., & Kökkaya, S. (2022) · Drug Metabolism and Personalized Therapy · doi:10.1515/dmpt-2022-0148 · Cited by 8 · see citing works

Thiotriazolin effectiveness in complex treatment of patients with post-COVID syndrome

Kryvenko, V. I., Kolesnyk, M. Y., Бєленічев, І. Ф., & Pavlov, S. V. (2021) · Zaporozhye Medical Journal · doi:10.14739/2310-1210.2021.3.229981 · Cited by 7 · see citing works

Mitochondrial hijacking: A potential mechanism for SARS-CoV-2 to impair female fertility

Sun, J., Liu, Q., Zhang, X., Dun, S., & Liu, L. (2022) · Medical Hypotheses · doi:10.1016/j.mehy.2022.110778 · Cited by 7 · see citing works

Single-cell RNA-sequencing data analysis reveals a highly correlated triphasic transcriptional response to SARS-CoV-2 infection

Sánchez, P. A. G., & Elena, S. F. (2022) · Communications Biology · doi:10.1038/s42003-022-04253-4 · Cited by 6 · see citing works

Pathway and Network Analyses Identify Growth Factor Signaling and MMP9 as Potential Mediators of Mitochondrial Dysfunction in Severe COVID-19

Wang, Y., Schughart, K., Pelaia, T. M., Chew, T., Kim, K., Karvunidis, T., Knippenberg, B., Teoh, S., Phu, A. L., Short, K. R., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032524 · Cited by 6 · see citing works

A naturally occurring mitochondrial genome variant confers broad protection from infection in Drosophila

Salminen, T. S., Vesala, L., Basikhina, Y., Kutzer, M. A. M., Tuomela, T., Lucas, R., Monteith, K. M., Prakash, A., Tietz, T., & Vale, P. F. (2024) · PLoS Genetics · doi:10.1371/journal.pgen.1011476 · Cited by 5 · see citing works

Post-Acute Sequelae and Mitochondrial Aberration in SARS-CoV-2 Infection

Ward, C., & Schlichtholz, B. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25169050 · Cited by 5 · see citing works

Environmental exposures and familial background alter the induction of neuropathology and inflammation after SARS-CoV-2 infection

Chatterjee, D., Kurup, D., & Smeyne, R. J. (2025) · npj Parkinson s Disease · doi:10.1038/s41531-025-00925-0 · Cited by 4 · see citing works

Salivary cortisol in long COVID: a marker of broader stress system and circadian rhythm dysregulation

Camici, M., Franco, M., Talamanca, L., Petino, M., Paulicelli, J., Scarnecchia, L., Ciavarella, L., Orzilli, T., Balducelli, F., Mazzotta, V., et al. (2026) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2025.1690698 · Cited by 4 · see citing works

How COVID-19 Brought Medical Gaslighting to the Forefront and Made Invisible Illness Visible: Lessons from the BIPOC Long COVID Study

Witvliet, M. G. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.107936 · Cited by 4 · see citing works

Urinary Mitochondrial Deoxyribonucleic Acid: A Novel Biomarker of Coronavirus Disease 2019-associated Acute Kidney Injury in Renal Transplant Recipients

Yadav, B., Prasad, N., Kushwaha, R. S., Patel, M. R., BHADAURIA, D. S., & Kaul, A. (2023) · Indian Journal of Transplantation · doi:10.4103/ijot.ijot_37_23 · Cited by 3 · see citing works

The Intersection of SARS-CoV-2 and Diabetes

Nichols, J. H., Smith, A. M., & Jonsson, C. B. (2025) · Microorganisms · doi:10.3390/microorganisms13061390 · Cited by 6 · see citing works

SLIRP promotes autoimmune diseases by amplifying antiviral signaling via positive feedback regulationPreprint

Ku, D., Yang, Y.-O., Park, Y., Jang, D., Lee, N., Lee, Y.-K., Lee, K., Lee, J., Han, Y.-O.-B., Jang, S., et al. (2024) · bioRxiv · doi:10.1101/2024.03.28.587146

Mitochondrial OXPHOS restricts SARS-CoV-2 replication

Albrecht, Y. E. S., Morrow, R. M., Kenney, D., Olali, A. Z., Wacquiez, A., Chehadeh, N., Cen, Z., Haltom, J., Chen, I. G., Ranshing, S., et al. (2026) · Science Advances · doi:10.1126/sciadv.adz3081 · Cited by 2 · see citing works

Evidence of mitochondria origin of SARS-CoV-2 double-membrane vesicles: a review.

Balderas, P. M. D. O. (2024) · F1000Research · doi:10.12688/f1000research.73170.3 · Cited by 2 · see citing works

Novel coronavirus vulnerability: metabolic derangements and altered dehydrogenase enzyme activities are central to the virus pathogenesis in human, bat and other animals

Manna, S. K. (2021) · Exploratory Animal and Medical Research · doi:10.52635/eamr/11.1.1-9 · Cited by 2 · see citing works

Direct causal variable discovery leveraging the invariance principle: application in biomedical studiesPreprint

Yin, L., Liu, M., Shi, Y., Qiu, J., & So, H.-C. (2024) · medRxiv · doi:10.1101/2024.08.29.24312763 · Cited by 2 · see citing works

Urinary Mitochondrial DNA Induces an Inflammatory Response in Peripheral Blood Mononuclear Cells

Yadav, B., Prasad, N., Kushwaha, R. S., Singh, A., Yadav, D., BHADAURIA, D. S., & Kaul, A. (2024) · Indian Journal of Transplantation · doi:10.4103/ijot.ijot_94_23 · Cited by 1 · see citing works

Pancreatic and Hepatic Injury in COVID-19: A Worse Prognosis in NAFLD Patients?

Mengual-Moreno, E., Nava, M., Manzano, A., Ariza, D. V., D’Marco, L., Castro, A. V., Marquina, M. A., Hernández, M., Corredor-Pereira, C., Checa-Ros, A., et al. (2024) · Biomedicines · doi:10.3390/biomedicines12020283 · Cited by 1 · see citing works

Evidence of mitochondria origin of SARS-CoV-2 double-membrane vesicles: a review.

Balderas, P. M. D. O. (2022) · F1000Research · doi:10.12688/f1000research.73170.2 · Cited by 1 · see citing works

Evidence of mitochondria origin of SARS-CoV-2 double-membrane vesicles: a review.

Balderas, P. M. D. O. (2021) · F1000Research · doi:10.12688/f1000research.73170.1

LONG-COVID: AN OUTCOME OF MITOCHONDRIAL DYSFUNCTION (A BRIEF NARRATIVE REVIEW)

Razdan, K., & Raina, V. (2022) · INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH · doi:10.36106/ijsr/3200814

Efeito das proteínas NSP4 e ORF9b de SARS-CoV-2 sobre a viabilidade celular e identificação de ligantes contra NSP4

Yonamine, D. K. (2023) · doi:10.11606/t.59.2023.tde-30012024-145043

Mitochondrial genome variation affects humoral and cell-mediated innate immune responses and infection outcomesPreprint

Salminen, T. S., Vesala, L., Basikhina, Y., Kutzer, M. A. M., Tuomela, T., Lucas, R., Monteith, K. M., Prakash, A., Tietz, T., & Vale, P. F. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.03.28.587162

Charnolosome nanotheranostics in infectious diseases (With Special Reference to COVID-19 infection)

Sharma, S. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-21752-4.00051-1

Analysis of the Functional Role of TIMM29 in the Hepatitis B Virus Life Cycle

Abueldahab, L., Suwanmanee, Y., Muriungi, N. G., Ohsaki, E., Wada, M., Kimura‐Ohba, S., & Ueda, K. (2025) · Microbiology and Immunology · doi:10.1111/1348-0421.13206

Additional file 3 of Human-derived air–liquid interface cultures decipher Alzheimer’s disease–SARS-CoV-2 crosstalk in the olfactory mucosa

Shahbaz, M. A., Kuivanen, S. H., Lampinen, R., Mussalo, L., Hron, T., Závodná, T., Ojha, R., Krejčík, Z., Saveleva, L., Tahir, N. A., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26654236

Additional file 1 of Human-derived air–liquid interface cultures decipher Alzheimer’s disease–SARS-CoV-2 crosstalk in the olfactory mucosa

Shahbaz, M. A., Kuivanen, S. H., Lampinen, R., Mussalo, L., Hron, T., Závodná, T., Ojha, R., Krejčík, Z., Saveleva, L., Tahir, N. A., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26654230

Additional file 2 of Human-derived air–liquid interface cultures decipher Alzheimer’s disease–SARS-CoV-2 crosstalk in the olfactory mucosa

Shahbaz, M. A., Kuivanen, S. H., Lampinen, R., Mussalo, L., Hron, T., Závodná, T., Ojha, R., Krejčík, Z., Saveleva, L., Tahir, N. A., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26654233

Additional file 5 of Human-derived air–liquid interface cultures decipher Alzheimer’s disease–SARS-CoV-2 crosstalk in the olfactory mucosa

Shahbaz, M. A., Kuivanen, S. H., Lampinen, R., Mussalo, L., Hron, T., Závodná, T., Ojha, R., Krejčík, Z., Saveleva, L., Tahir, N. A., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26654242

Additional file 4 of Human-derived air–liquid interface cultures decipher Alzheimer’s disease–SARS-CoV-2 crosstalk in the olfactory mucosa

Shahbaz, M. A., Kuivanen, S. H., Lampinen, R., Mussalo, L., Hron, T., Závodná, T., Ojha, R., Krejčík, Z., Saveleva, L., Tahir, N. A., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26654239

Hsa_circ_0009910/hsa-miR-145-5p/IFNB1 Axis Potential Role in the Immunopathogenesis of COVID-19 Disease

Shahi, A., Firoozi, Z., Mohammadisoleimani, E., Mirzaei, E., Sarvi, M., Darbeheshti, F., Karimi, J., Montaseri, Z., & Mansoori, Y. (2025) · Genetic Testing and Molecular Biomarkers · doi:10.1177/19450265251406027

Mitochondrial Dysfunction and Telomeric Shortening as Long-term Complications After COVID-19

Mulet, A., Signes‐Costa, J., Fernández‐Fabrellas, E., Ros, J. A., Rodriguez-Portal, J. A., Andreu, A. L., Pallardó, F. V., & González‐Cabo, P. (2026) · Archivos de Bronconeumología · doi:10.1016/j.arbres.2026.03.018

Plasma Membrane Redox Failure Links COVID-19 Metabolic Stress to Ferroptotic Neurodegeneration

Lee, J., Hwang, H., & Hyun, D. (2026) · Antioxidants · doi:10.3390/antiox15050572

SARS-CoV-2 induces a unique mitochondrial transcriptome signaturePreprint

Miller, B., Silverstein, A. R., Flores, M., Xiang, W., Cao, K., Kumagai, H., Mehta, H. H., Yen, K., Kim, S., & Cohen, P. (2020) · doi:10.21203/rs.3.rs-36568/v1 · Cited by 10 · see citing works

Sex differences in antiviral immunity in SARS‐CoV‐2 infection: Mitochondria and mitomiR come into view

Iessi, E., Cittadini, C., Anticoli, S., Fecchi, K., Matarrese, P., & Ruggieri, A. (2020) · Acta Physiologica · doi:10.1111/apha.13571 · Cited by 11 · see citing works

Exploring Key Regulators of Mitochondrial Dynamics and Immune Response in SARS-CoV-2 Infection

de Melo, T. C., Valerio, H. P., Trevisan-Silva, D., de Souza, M. M., de Melo, A. T., Flores, M. P. A., Oliveira, D. S., Gomes, R. N., Machado‐Santelli, G. M., Ribeiro, B. F. M., et al. (2026) · Viruses · doi:10.3390/v18060675

Pathophysiological involvement of host mitochondria in SARS-CoV-2 infection that causes COVID-19: a comprehensive evidential insight

Bhowal, C., Ghosh, S., Ghatak, D., & De, R. (2022) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-022-04593-z · Cited by 63 · see citing works

Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts

Guarnieri, J. W., Dybas, J. M., Fazelinia, H., Kim, M. S., Frere, J. J., Zhang, Y., Albrecht, Y. E. S., Murdock, D. G., Angelin, A., Singh, L. N., et al. (2023) · Science Translational Medicine · doi:10.1126/scitranslmed.abq1533 · Cited by 191 · see citing works