Serotonin modulates asymmetric learning from reward and punishment in healthy human volunteers

Michely, Jochen; Eldar, Eran; Erdman, Alon; Martin, Ingrid M.; Dolan, Raymond J.

doi:10.1038/s42003-022-03690-5

Serotonin modulates asymmetric learning from reward and punishment in healthy human volunteers

Instrumental learning is driven by a history of outcome success and failure. Here, we examined the impact of serotonin on learning from positive and negative outcomes. Healthy human volunteers were assessed twice, once after acute (single-dose), and once after prolonged (week-long) daily administ…