The DOI matches its Crossref record.
A Simpler Origin for Life
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Despite the conceptual elegance of the RNA world, this hypothesis faces formidable difficulties, primarily the immense challenge of RNA synthesis under plausible prebiotic conditions [22,40,41].”
From The Origin of Prebiotic Information System in the Peptide/RNA World: A Simulation Model of the Evolution of Translation and the Genetic Code (2019) · cites this paper as [40]
In the citing paper
“Initially, all of these mononucleotides were randomly polymerized into short oligonucleotides of different lengths by peptide bonding [40].”
From The Origin of Prebiotic Information System in the Peptide/RNA World: A Simulation Model of the Evolution of Translation and the Genetic Code (2019) · cites this paper as [40]
Citations
Cites
Still being checked.
Cited by
Sorted by citations
Items 101–124 of 124
Higgs, P. G. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800049-6.00164-5
The Information PathwayPreprint
Gowan, J. A. (2009) · viXra
Hafstad, A. (2018) · The Clinical Journal of the International Institute for Bioenergetic Analysis · doi:10.30820/0743-4804-2018-28-27
La misteriosa energía de la vida
Hafstad, A. (2018) · The Clinical Journal of the International Institute for Bioenergetic Analysis · doi:10.30820/0743-4804-2018-28-es-29
Bersini, H. (2014) · Encyclopedia of Astrobiology · doi:10.1007/978-3-642-27833-4_110-2
Morvillo, N. (2010) · Wiley eBooks · doi:10.1002/9781444317299.furread
Lancet, D. (2015) · Encyclopedia of Astrobiology · doi:10.1007/978-3-662-44185-5_5133
(2015) · Wiley eBooks · doi:10.1002/9781118539385.ch6 · Cited by 1
Bersini, H. (2015) · Encyclopedia of Astrobiology · doi:10.1007/978-3-662-44185-5_110
Bersini, H. (2023) · Encyclopedia of Astrobiology · doi:10.1007/978-3-662-65093-6_110
Lancet, D. (2023) · Encyclopedia of Astrobiology · doi:10.1007/978-3-662-65093-6_5133
The RNA World: Reality or Dogma?
Chatterjee, S. (2023) · Springer eBooks · doi:10.1007/978-3-031-23397-5_10
Shapiro, I. M., & Landis, W. J. (2023) · Springer eBooks · doi:10.1007/978-3-031-34304-9_1
Focusing on Dynamics: When an Exception Becomes a Rule
Peretti, A. V., Calbacho-Rosa, L. S., Olivero, P. A., Oviedo‐Diego, M. A., & Vrech, D. E. (2024) · Springer eBooks · doi:10.1007/978-3-031-55382-0_6
An Ensemble Approach to the Origin of Life
Alicea, B., Ahmad, B., & Gordon, R. (2024) · Wiley eBooks · doi:10.1002/9781119901228.ch8
A New Approach to Defining Life
Akkerhuis, G. A. J. M. J. O. (2024) · Library of ethics and applied philosophy · doi:10.1007/978-3-031-73205-8_17
Phylogenetic Analysis: Early Evolution of Life
Sarma, H., Pradhan, S., Mattaparthi, V. S. K., & Kaushik, S. (2019) · Elsevier eBooks · doi:10.1016/b978-0-323-95502-7.00307-9
Denial and Dissolution – Architecture’s Futile Battle Against Entropy
Futerfas, E. (2025) · react/review a responsive journal for art and architecture · doi:10.5070/r5.40226
Mimicking C-C bond forming reactions of core metabolism
Varma, S. J. (2018) · theses.fr (ABES) · doi:10.70675/900a41d3z033dz4e25z92faz42efaf5d1324
L’émergence de l’esprit : une approche énactive de la vie mentale
Devers, N. (2025) · theses.fr (ABES) · doi:10.70675/457bdb06z15a9z456bzafdcz0027b7cd4d38
Emergent Rhythmicity in Proteinoid-BZ Hybrid Systems
Mougkogiannis, P., & Adamatzky, A. (2026) · ACS Synthetic Biology · doi:10.1021/acssynbio.6c00227
Cai, J. (2026) · SSRN Electronic Journal · doi:10.2139/ssrn.7038290
Alekhina, O. M., Bashkirov, P. V., Silantyev, A. S., Dudik, S. P., Matyushkina, D. S., Shcherbakova, O. V., & Govorun, V. M. (2026) · Acta Naturae · doi:10.32607/actanaturae.27965
Rauchfuss, H., & Mitchell, T. N. (2008) · Springer eBooks · doi:10.1007/978-3-540-78823-2_6
Metadata
- Authors
- Shapiro, R.
- Affiliations
- New York University (US)
- Corresponding author
- Shapiro, Robert
- Venue
- Scientific American
- Published
- 2007-06
- Volume
- 296
- Issue
- 6
- Pages
- 46-53
- ISSN
- 0036-8733 (ISSN-L)
- OpenAlex
- W2054282731
- Cited by
- 125
- References
- 0
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 6 · 2023: 13 · 2022: 8 · 2021: 2 · 2020: 3 · 2019: 6 · 2018: 8 · 2017: 3 · 2016: 3 · 2015: 10 · 2014: 4 · 2013: 9 · 2012: 9
- FWCI
- 5.37
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Scientific American (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Keywords
- origin of life, prebiotic chemistry
- MeSH terms
- Origin of Life, DNA, Energy Metabolism, Genetic Code, RNA, Evolution, Molecular, Life
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
