The DOI matches its Crossref record.
A Simpler Origin for Life
Overview
Integrity signals
Registry
Cites
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Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Despite the conceptual elegance of the RNA world, this hypothesis faces formidable difficulties, primarily the immense challenge of RNA synthesis under plausible prebiotic conditions [22,40,41].”
From The Origin of Prebiotic Information System in the Peptide/RNA World: A Simulation Model of the Evolution of Translation and the Genetic Code (2019) · cites this paper as [40]
In the citing paper
“Initially, all of these mononucleotides were randomly polymerized into short oligonucleotides of different lengths by peptide bonding [40].”
From The Origin of Prebiotic Information System in the Peptide/RNA World: A Simulation Model of the Evolution of Translation and the Genetic Code (2019) · cites this paper as [40]
Citations
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Still being checked.
Cited by
Sorted by citations
Prebiotic Systems Chemistry: New Perspectives for the Origins of Life
Ruiz-Mirazo, K., Briones, C., & de la Escosura, A. (2014) · Chemical Reviews · doi:10.1021/cr2004844 · Cited by 930
The RNA World: molecular cooperation at the origins of life
Higgs, P. G., & Lehman, N. (2015) · Nature Reviews Genetics · doi:10.1038/nrg3841 · Cited by 604
The Origin of Life—Out of the Blue
Sutherland, J. D. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201506585 · Cited by 401
Vasas, V., Fernando, C., Santos, M., Kauffman, S., & Szathmáry, E. (2012) · Biology Direct · doi:10.1186/1745-6150-7-1 · Cited by 369
Asphalt, Water, and the Prebiotic Synthesis of Ribose, Ribonucleosides, and RNA
Benner, S. A., Kim, H.-J., & Carrigan, M. A. (2012) · Accounts of Chemical Research · doi:10.1021/ar200332w · Cited by 281
Metadata
- Authors
- Shapiro, R.
- Affiliations
- New York University (US)
- Corresponding author
- Shapiro, Robert
- Venue
- Scientific American
- Published
- 2007-06
- Volume
- 296
- Issue
- 6
- Pages
- 46-53
- ISSN
- 0036-8733 (ISSN-L)
- OpenAlex
- W2054282731
- Cited by
- 125
- References
- 0
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 6 · 2023: 13 · 2022: 8 · 2021: 2 · 2020: 3 · 2019: 6 · 2018: 8 · 2017: 3 · 2016: 3 · 2015: 10 · 2014: 4 · 2013: 9 · 2012: 9
- FWCI
- 5.37
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Scientific American (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Keywords
- origin of life, prebiotic chemistry
- MeSH terms
- Origin of Life, DNA, Energy Metabolism, Genetic Code, RNA, Evolution, Molecular, Life
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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