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A Simpler Origin for Life
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“Despite the conceptual elegance of the RNA world, this hypothesis faces formidable difficulties, primarily the immense challenge of RNA synthesis under plausible prebiotic conditions [22,40,41].”
From The Origin of Prebiotic Information System in the Peptide/RNA World: A Simulation Model of the Evolution of Translation and the Genetic Code (2019) · cites this paper as [40]
In the citing paper
“Initially, all of these mononucleotides were randomly polymerized into short oligonucleotides of different lengths by peptide bonding [40].”
From The Origin of Prebiotic Information System in the Peptide/RNA World: A Simulation Model of the Evolution of Translation and the Genetic Code (2019) · cites this paper as [40]
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Metadata
- Authors
- Shapiro, R.
- Affiliations
- New York University (US)
- Corresponding author
- Shapiro, Robert
- Venue
- Scientific American
- Published
- 2007-06
- Volume
- 296
- Issue
- 6
- Pages
- 46-53
- ISSN
- 0036-8733 (ISSN-L)
- OpenAlex
- W2054282731
- Cited by
- 125
- References
- 0
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 6 · 2023: 13 · 2022: 8 · 2021: 2 · 2020: 3 · 2019: 6 · 2018: 8 · 2017: 3 · 2016: 3 · 2015: 10 · 2014: 4 · 2013: 9 · 2012: 9
- FWCI
- 5.37
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Scientific American (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Keywords
- origin of life, prebiotic chemistry
- MeSH terms
- Origin of Life, DNA, Energy Metabolism, Genetic Code, RNA, Evolution, Molecular, Life
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