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Brain Genomics Superstruct Project initial data release with structural, functional, and behavioral measures
Open accessAbstract
The goal of the Brain Genomics Superstruct Project (GSP) is to enable large-scale exploration of the links between brain function, behavior, and ultimately genetic variation. To provide the broader scientific community data to probe these associations, a repository of structural and functional magnetic resonance imaging (MRI) scans linked to genetic information was constructed from a sample of healthy individuals. The initial release, detailed in the present manuscript, encompasses quality screened cross-sectional data from 1,570 participants ages 18 to 35 years who were scanned with MRI and completed demographic and health questionnaires. Personality and cognitive measures were obtained on a subset of participants. Each dataset contains a T1-weighted structural MRI scan and either one (n=1,570) or two (n=1,139) resting state functional MRI scans. Test-retest reliability datasets are included from 69 participants scanned within six months of their initial visit. For the majority of participants self-report behavioral and cognitive measures are included (n=926 and n=892 respectively). Analyses of data quality, structure, function, personality, and cognition are presented to demonstrate the dataset’s utility.
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Metadata
- Authors
- Holmes, A. J., Hollinshead, M. O., O’Keefe, T. M., Petrov, V. I., Fariello, G. R., Wald, L. L., Fischl, B., Rosen, B. R., Mair, R. W., Roffman, J. L., Smoller, J. W., & Buckner, R. L.
- Venue
- Scientific Data
- Published
- 2015-07-07
- Volume
- 2
- Issue
- 1
- Pages
- 150031-150031
- ISSN
- 2052-4463 (ISSN-L)
- OpenAlex
- W1458229720
- Cited by
- 444
- References
- 83
- Type
- data paper
- Language
- en
- Open access
- gold
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- Holmes, A. J., Hollinshead, M. O., O’Keefe, T. M., Petrov, V. I., Fariello, G. R., Wald, L. L., Fischl, B., Rosen, B. R., Mair, R. W., Roffman, J. L., Smoller, J. W., & Buckner, R. L. (2015). Brain Genomics Superstruct Project initial data release with structural, functional, and behavioral measures. Scientific Data. https://doi.org/10.1038/sdata.2015.31
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