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Whole grain consumption and risk of colorectal cancer: a population-based cohort of 60 000 women

Open access
Larsson, S C, Giovannucci, E, Bergkvist, L, Wolk, A·2005·British Journal of Cancer

Abstract

We examined prospectively the association between whole grain consumption and colorectal cancer risk in the population-based Swedish Mammography Cohort. A total of 61,433 women completed a food-frequency questionnaire at baseline (1987-1990) and, through linkage with the Swedish Cancer Registry, 805 incident cases of colorectal cancer were identified during a mean follow-up of 14.8 years. High consumption of whole grains was associated with a lower risk of colon cancer, but not of rectal cancer. The multivariate rate ratio (RR) of colon cancer for the top category of whole grain consumption (> or = 4.5 servings day(-1)) compared with the bottom category (<1.5 servings day(-1)) was 0.67 (95% confidence interval (CI), 0.47-0.96; P-value for trend=0.06). The corresponding RR after excluding cases occurring within the first 2 years of follow-up was 0.65 (95% CI, 0.45-0.94; P-value for trend=0.04). Our findings suggest that high consumption of whole grains may decrease the risk of colon cancer in women.

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Metadata

Authors
Larsson, S. C., Giovannucci, E., Bergkvist, L., & Wolk, A.
Venue
British Journal of Cancer
Published
2005-04-12
Volume
92
Issue
9
Pages
1803-1807
ISSN
  • 0007-0920 (ISSN-L)
  • 1532-1827
OpenAlex
W2091050557
Cited by
209
References
2
FWCI
9.70
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Whole grain consumption and risk of colorectal cancer: a population-based cohort of 60 000 women. https://app.cochat.ai/papers/10.1038/sj.bjc.6602543
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Larsson, S. C., Giovannucci, E., Bergkvist, L., & Wolk, A. (2005). Whole grain consumption and risk of colorectal cancer: a population-based cohort of 60 000 women. British Journal of Cancer. https://doi.org/10.1038/sj.bjc.6602543

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