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Cited by 276

The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.

Opium, tobacco, and alcohol use in relation to oesophageal squamous cell carcinoma in a high-risk area of Iran

Open access
Nasrollahzadeh, D, Kamangar, F, Aghcheli, K, Sotoudeh, M, Islami, F, Abnet, C C, Shakeri, R, Pourshams, A, Marjani, H A, Nouraie, M, Khatibian, M, Semnani, S, Ye, W, Boffetta, P, Dawsey, S M, Malekzadeh, R·2008·British Journal of Cancer

Abstract

The very high incidence of oesophageal squamous cell carcinoma (ESCC) in Golestan Province in northeastern Iran was suggested by studies in the 1970s as partly due to opium use, which is not uncommon in this area, but based on limited numbers. From December 2003 to June 2007, we administered a validated structured questionnaire to 300 ESCC cases and 571 controls, matched on neighbourhood of residence, age (+/-2 years), and sex. We used conditional logistic regression models to calculate odds ratios (ORs) and 95% confidence intervals (95% CIs) adjusted for potential confounders. Compared with those who used neither tobacco nor opium, risk of ESCC was increased in those who used tobacco only (OR, 95% CI: 1.70, 1.05-2.73), in those who used opium only (2.12, 1.21-3.74), and in those who used both tobacco and opium (2.35, 1.50-3.67). All forms of tobacco use (cigarettes, hookah, and nass) were associated with higher ESCC risk. Similarly, use of both crude opium and other forms of opium were associated with higher risk. Alcohol consumption was seen in only 2% of the cases and 2% of the controls, and was not associated with ESCC risk.

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Metadata

Authors
Nasrollahzadeh, D., Kamangar, F., Aghcheli, K., Sotoudeh, M., Islami, F., Abnet, C. C., Shakeri, R., Pourshams, A., Marjani, H. A., Nouraie, M., Khatibian, M., Semnani, S., Ye, W., Boffetta, P., Dawsey, S. M., & Malekzadeh, R.
Venue
British Journal of Cancer
Published
2008-05-13
Volume
98
Issue
11
Pages
1857-1863
ISSN
  • 0007-0920 (ISSN-L)
  • 1532-1827
OpenAlex
W2036463999
Cited by
276
References
20
FWCI
14.87
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Opium, tobacco, and alcohol use in relation to oesophageal squamous cell carcinoma in a high-risk area of Iran. https://app.cochat.ai/papers/10.1038/sj.bjc.6604369
The paper
Nasrollahzadeh, D., Kamangar, F., Aghcheli, K., Sotoudeh, M., Islami, F., Abnet, C. C., Shakeri, R., Pourshams, A., Marjani, H. A., Nouraie, M., Khatibian, M., Semnani, S., Ye, W., Boffetta, P., Dawsey, S. M., & Malekzadeh, R. (2008). Opium, tobacco, and alcohol use in relation to oesophageal squamous cell carcinoma in a high-risk area of Iran. British Journal of Cancer. https://doi.org/10.1038/sj.bjc.6604369

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.