β 1 ‐ and β 2 ‐adrenoceptor responses in cardiomyocytes derived from human embryonic stem cells: comparison with failing and non‐failing adult human heart

Background and purpose: Characterization of human embryonic stem cell‐derived cardiomyocytes (hESC‐CM) in relation to adult myocytes is essential for their future use in transplantation or as a model system. The β‐adrenoceptor pathways, which are known to be effective early in hESC‐CM development…