Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration

The Inflammasome

Martinon, F., Burns, K., & Tschopp, J. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00599-3 · Cited by 6,066

Gout-associated uric acid crystals activate the NALP3 inflammasome

Martinon, F., Pétrilli, V., Mayor, A., Tardivel, A., & Tschopp, J. (2006) · Nature · doi:10.1038/nature04516 · Cited by 5,326

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

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Cryopyrin activates the inflammasome in response to toxins and ATP

Mariathasan, S., Weiss, D. S., Newton, K., McBride, J., O'Rourke, K., Roose-Girma, M., Lee, W. P., Weinrauch, Y., Monack, D. M., & Dixit, V. M. (2006) · Nature · doi:10.1038/nature04515 · Cited by 3,080

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

Mariathasan, S., Newton, K., Monack, D. M., Vucic, D., French, D. M., Lee, W. P., Roose-Girma, M., Erickson, S. L., & Dixit, V. M. (2004) · Nature · doi:10.1038/nature02664 · Cited by 1,864

NALP3 Forms an IL-1β-Processing Inflammasome with Increased Activity in Muckle-Wells Autoinflammatory Disorder

Agostini, L., Martinon, F., Burns, K., McDermott, M. F., Hawkins, P. N., & Tschopp, J. (2004) · Immunity · doi:10.1016/s1074-7613(04)00046-9 · Cited by 1,768

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

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Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages

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Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf

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NOD-LRR PROTEINS: Role in Host-Microbial Interactions and Inflammatory Disease

Inohara, N., Chamaillard, M., McDonald, C., & Núñez, G. (2005) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.74.082803.133347 · Cited by 1,019

NLRP3 Inflammasome and Inflammatory Response in Aging Disorders: The Entanglement of Redox Modulation in Different Outcomes

Chhunchha, B., Kubo, E., Lehri, D., & Singh, D. P. (2025) · Cells · doi:10.3390/cells14130994 · Cited by 30

TLRs, NLRs and RLRs: Innate sensors and their impact on allergic diseases – A current view

Heine, H. (2011) · Immunology Letters · doi:10.1016/j.imlet.2011.04.010 · Cited by 27

Sphingosine Kinases are Involved in Macrophage NLRP3 Inflammasome Transcriptional Induction

Syed, S. N., Weigert, A., & Brüne, B. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21134733 · Cited by 28

Mushroom Natural Products in Neurodegenerative Disease Drug Discovery

Abitbol, A., Mallard, B., Tiralongo, E., & Tiralongo, J. (2022) · Cells · doi:10.3390/cells11233938 · Cited by 30

Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis

Neuwirt, E., Magnani, G., Ćiković, T., Wöhrle, S., Fischer, L., Kostina, A., Flemming, S., Fischenich, N. J., Saller, B. S., Gorka, O., et al. (2023) · Science Signaling · doi:10.1126/scisignal.abh1083 · Cited by 29

NOD-like Receptors—Emerging Links to Obesity and Associated Morbidities

Bauer, S., Hezinger, L., Rexhepi, F., Ramanathan, S., & Kufer, T. A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24108595 · Cited by 26

SOCS-1 Suppresses Inflammation Through Inhibition of NALP3 Inflammasome Formation in Smoke Inhalation-Induced Acute Lung Injury

Zhang, L., Xu, C., Chen, X., Shi, Q., Su, W., & Zhao, H. (2018) · Inflammation · doi:10.1007/s10753-018-0802-y · Cited by 26

Streptococcus mutans activates the AIM2, NLRP3 and NLRC4 inflammasomes in human THP-1 macrophages

Song, Y., Na, H. S., Park, E.-J., Park, M. H., Lee, H. A., & Chung, J. (2018) · International Journal of Oral Science · doi:10.1038/s41368-018-0024-z · Cited by 27

Brucella abortus nitric oxide metabolite regulates inflammasome activation and IL‐1β secretion in murine macrophages

Campos, P. C., Gomes, M. T. R., Marinho, F. V., Guimarães, E. S., Cruz, M. G. F. D. M. L., & Oliveira, S. C. (2019) · European Journal of Immunology · doi:10.1002/eji.201848016 · Cited by 26

NLRP3 gain-of-function in CD4+ T lymphocytes ameliorates experimental autoimmune encephalomyelitis

Braga, T. T., Brandão, W. N., de Azevedo, H. F. Z., Terra, F. F., de Melo, A. C. L., Pereira, F. V., Andrade‐Oliveira, V., Hiyane, M. I., Peron, J. P. S., & Câmara, N. O. S. (2019) · Clinical Science · doi:10.1042/cs20190506 · Cited by 29

The pathogenesis of neonatal autoimmune and autoinflammatory diseases: A comprehensive review

Chang, C. (2013) · Journal of Autoimmunity · doi:10.1016/j.jaut.2012.12.010 · Cited by 25

Epithelial PI3K-δ Promotes House Dust Mite-Induced Allergic Asthma in NLRP3 Inflammasome-Dependent and -Independent Manners

Kim, S. R., Park, H. J., Lee, K.-B., Kim, H. J., Jeong, J. S., Cho, S., & Lee, Y. C. (2020) · Allergy Asthma and Immunology Research · doi:10.4168/aair.2020.12.2.338 · Cited by 26

Cardiac glycosides cause cytotoxicity in human macrophages and ameliorate white adipose tissue homeostasis

Olona, A., Hateley, C., Guerrero, A., Ko, J., Johnson, M. R., Anand, P., Thomas, D., Gil, J., & Behmoaras, J. V. (2021) · British Journal of Pharmacology · doi:10.1111/bph.15423 · Cited by 24

Mycobacterium tuberculosis stimulates IL-1β production by macrophages in an ESAT-6 dependent manner with the involvement of serum amyloid A3

Jung, B., Vankayalapati, R., & Samten, B. (2021) · Molecular Immunology · doi:10.1016/j.molimm.2021.04.022 · Cited by 25

How SARS-CoV-2 might affect potassium balance via impairing epithelial sodium channels?

Noori, M., Nejadghaderi, S. A., Sullman, M. J. M., Carson‐Chahhoud, K., Ardalan, M., Kolahi, A., & Safiri, S. (2021) · Molecular Biology Reports · doi:10.1007/s11033-021-06642-0 · Cited by 28

Diabetic Kidney Disease: From Pathogenesis to Novel Treatment Possibilities

Aboolian, A., Urner, S., Roden, M., Jha, J. C., & Jandeleit-Dahm, K. A. M. (2022) · Handbook of experimental pharmacology · doi:10.1007/164_2021_576 · Cited by 25

Gasdermins and pannexin-1 mediate pathways of chemotherapy-induced cell lysis in hematopoietic malignancies

Zhou, B., Ryder, C. B., Dubyak, G., & Abbott, D. W. (2022) · Science Signaling · doi:10.1126/scisignal.abl6781 · Cited by 25

ASC oligomer favors caspase-1CARD domain recruitment after intracellular potassium efflux

Martín‐Sánchez, F., Compan, V., Peñín‐Franch, A., Tapia‐Abellán, A., Gómez, A. I., Baños-Gregori, M. C., Schmidt, F. I., & Pelegrín, P. (2023) · The Journal of Cell Biology · doi:10.1083/jcb.202003053 · Cited by 27

SYK kinase signaling and the NLRP3 inflammasome in antifungal immunity

Poeck, H., & Ruland, J. (2010) · Journal of Molecular Medicine · doi:10.1007/s00109-010-0631-4 · Cited by 25

Busulfan and cyclosphamide induce liver inflammation through NLRP3 activation in mice after hematopoietic stem cell transplantation

Qiao, J., Huang, Y., Xia, Y., Chu, P., Yao, H., Xu, L., Qi, K., Liu, Y., Xu, K., & Zeng, L. (2015) · Scientific Reports · doi:10.1038/srep17828 · Cited by 25

Detection of In Vivo Inflammasome Activation for Predicting Sepsis Mortality

Cui, J. Z., Oehrl, S., Ahmad, F., Brenner, T., Uhle, F., Nußhag, C., Rupp, C., Funck, F., Meisel, S., Weigand, M. A., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2020.613745 · Cited by 24

The role of Nod-like receptor protein 3 inflammasome activated by ion channels in multiple diseases

Xu, X.-L., Wu, X., Yue, G., An, Q., Lou, J. Q., Yang, X., Jin, Z., Ding, J., Hu, Y., Du, Q., et al. (2022) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-022-04602-1 · Cited by 27

Apilimod activates the NLRP3 inflammasome through lysosome-mediated mitochondrial damage

Hou, Y., He, H., Ma, M., & Zhou, R. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1128700 · Cited by 24

Implications of Protein Post-Translational Modifications in IBD

Ehrentraut, S., & Colgan, S. P. (2012) · Inflammatory Bowel Diseases · doi:10.1002/ibd.22859 · Cited by 25

For Better or Worse: Cytosolic DNA Sensing during Intracellular Bacterial Infection Induces Potent Innate Immune Responses

Patrick, K. L., Bell, S. L., & Watson, R. O. (2016) · Journal of Molecular Biology · doi:10.1016/j.jmb.2016.04.030 · Cited by 24

General Strategies in Inflammasome Biology

Dubois, H., Wullaert, A., & Lamkanfi, M. (2016) · Current topics in microbiology and immunology · doi:10.1007/978-3-319-41171-2_1 · Cited by 26

Opportunities for future therapeutic interventions for hyperoxaluria: targeting oxidative stress

Joshi, S. N., & Khan, S. R. (2019) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2019.1599359 · Cited by 24

Sulforaphane decreases oxidative stress and inhibits NLRP3 inflammasome activation in a mouse model of ulcerative colitis

Zhou, Z., Dong, J., Qiu, Y., Zhang, G., Wei, K., He, L., Sun, Y., Jiang, H., Zhang, S., Guo, X., et al. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116706 · Cited by 26

An optimized whole blood assay measuring expression and activity of NLRP3, NLRC4 and AIM2 inflammasomes

Grinstein, L., Endter, K., Hedrich, C. M., Reinke, S., Luksch, H., Schulze, F., Robertson, A. A. B., Cooper, M. A., Rösen‐Wolff, A., & Winkler, S. (2017) · Clinical Immunology · doi:10.1016/j.clim.2017.11.011 · Cited by 21

Development of a molecular K+ probe for colorimetric/fluorescent/photoacoustic detection of K+

Ning, J., Lin, X., Su, F., Sun, A., Liu, H., Luo, J., Wang, L., & Tian, Y. (2020) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-020-02826-y · Cited by 23

Antimycin A-induced mitochondrial dysfunction regulates inflammasome signaling in human retinal pigment epithelial cells

Korhonen, E., Hytti, M., Piippo, N., Kaarniranta, K., & Kauppinen, A. (2021) · Experimental Eye Research · doi:10.1016/j.exer.2021.108687 · Cited by 23

Walking down Skeletal Muscle Lane: From Inflammasome to Disease

Dubuisson, N., Versele, R., de Carrizosa, M. A. D., Selvais, C. M., Brichard, S. M., & Abou‐Samra, M. (2021) · Cells · doi:10.3390/cells10113023 · Cited by 23

NLRP3 Inhibition Leads to Impaired Mucosal Fibroblast Function in Patients with Inflammatory Bowel Diseases

Weber, S., Sitte, S., Voegele, A.-L., Sologub, L., Wilfer, A., Räth, T., Nägel, A., Zundler, S., Franchi, L., Opipari, A. W., et al. (2023) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjad164 · Cited by 23

Immune system in renal injury and repair: Burning the candle from both ends?

Goligorsky, M. S. (2008) · Pharmacological Research · doi:10.1016/j.phrs.2008.05.011 · Cited by 23

Calcium-Independent Phospholipase A2β Is Dispensable in Inflammasome Activation and Its Inhibition by Bromoenol Lactone

Franchi, L., Chen, G., Marina–García, N., Abe, A., Qu, Y., Bao, S. S., Shayman, J. A., TURK, J. W., Dubyak, G., & Núñez, G. (2009) · Journal of Innate Immunity · doi:10.1159/000227263 · Cited by 23

Discovery and Development of NLRP3 Inhibitors Targeting the LRR Domain to Disrupt NLRP3-NEK7 Interaction for the Treatment of Rheumatoid Arthritis

Li, B., Li, P., Wei, L.-Y., Zou, J., Wang, Y., You, Q., Jiang, C., Di, B., & Xu, L. (2024) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.3c02407 · Cited by 23

New insights into TRP channels

Han, H.-R., & Yi, F. (2014) · Channels · doi:10.4161/chan.27178 · Cited by 16

TI: NLRP3 Inflammasome-Dependent Pyroptosis in CNS Trauma: A Potential Therapeutic Target

Zhou, C., Zheng, J., Fan, Y., & Wu, J. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.821225 · Cited by 23

DAMPs and influenza virus infection in ageing

Samy, R. P., & Lim, L. H. K. (2015) · Ageing Research Reviews · doi:10.1016/j.arr.2015.07.005 · Cited by 23

Sevoflurane Combined with ATP Activates Caspase-1 and Triggers Caspase-1-Dependent Pyroptosis in Murine J774 Macrophages

Jin, Y., Li, H., Xie, G., Chen, S., Wu, S., & Fang, X. (2012) · Inflammation · doi:10.1007/s10753-012-9550-6 · Cited by 22

Saikosaponin‑d alleviates carbon‑tetrachloride induced acute hepatocellular injury by inhibiting oxidative stress and NLRP3 inflammasome activation in the HL‑7702 cell line

Lin, L., Que, R., Shen, Y., Chen, Y., Yan, N., & Li, Y. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.8849 · Cited by 22

Inflammasome activation in bovine monocytes by extracellular ATP does not require the purinergic receptor P2X7

Hussen, J., Düvel, A., Koy, M., & Schuberth, H. (2012) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2012.06.004 · Cited by 22

TRPV1 modulated NLRP3 inflammasome activation via calcium in experimental subarachnoid hemorrhage

Zhang, K., Qin, Z., Chen, J., Guo, G., Jiang, X., Wang, F., Zhuang, J., & Zhang, Z. (2024) · Aging · doi:10.18632/aging.205379 · Cited by 21

Natural Products as a Novel Therapeutic Strategy for NLRP3 Inflammasome-Mediated Gout

Lee, J. H., Kim, H. S., Lee, J., Yang, G., & Kim, H. J. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.861399 · Cited by 22

Emerging Mechanisms and Targeted Therapy of Pyroptosis in Central Nervous System Trauma

Yang, B., Zhong, W., Gu, Y., & Li, Y. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.832114 · Cited by 21

Inhibition of sphingosine-1-phosphate receptor 3 suppresses ATP-induced NLRP3 inflammasome activation in macrophages via TWIK2-mediated potassium efflux

Wang, Y., Wang, C., He, Q., Chen, G., Yu, J., Cang, J., & Zhong, M. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1090202 · Cited by 21

Effect of enterohaemorrhagic E scherichia coli O 157: H 7‐specific enterohaemolysin on interleukin‐1β production differs between human and mouse macrophages due to the different sensitivity of NLRP 3 activation

Cheng, Y., Song, L., Huang, Y., Xiong, Y., Zhang, X., Sun, H., Zhu, X., Meng, G., Xu, J., & Ren, Z. (2015) · Immunology · doi:10.1111/imm.12442 · Cited by 21

Etiology and Pathogenesis of Hyperuricemia and Gout

Keenan, R. T., Nowatzky, J., & Pillinger, M. H. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4377-1738-9.00094-3 · Cited by 20

NOD-like receptor(s) and host immune responses with Pseudomonas aeruginosa infection

Alhazmi, A. (2018) · Inflammation Research · doi:10.1007/s00011-018-1132-0 · Cited by 22

Host Detection and the Stealthy Phenotype in Influenza Virus Infection

Dash, P., & Thomas, P. G. (2014) · Current topics in microbiology and immunology · doi:10.1007/82_2014_412 · Cited by 21

The Inflammasome in Host Defense

Chen, G., & Pedra, J. H. F. (2009) · Sensors · doi:10.3390/s100100097 · Cited by 25

NLRP1 inflammasome in neurodegenerative disorders: From pathology to therapies

Zhang, M.-J., Yang, L., Li, Z.-Y., Zhou, L.-Y., Wang, Y.-J., Wang, H.-S., Cui, X.-J., & Yao, M. (2024) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2024.10.004 · Cited by 21

PM2.5 exposure inducing ATP alteration links with NLRP3 inflammasome activation

Zeng, X., Liu, D., Wu, W., & Huo, X. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-021-16405-w · Cited by 20

The NLRP3 Inflammasome in Stress Response: Another Target for the Promiscuous Cannabidiol

dos Santos, A. H., Vila-Verde, C., Guimarães, F. S., Joca, S. R. L., & Lisboa, S. F. D. S. (2022) · Current Neuropharmacology · doi:10.2174/1570159x20666220411101217 · Cited by 20

A Highly Selective Mitochondria‐Targeting Fluorescent K+ Sensor

Kong, X., Su, F., Zhang, L., Yaron, J. R., Lee, F., Shi, Z., Tian, Y., & Meldrum, D. R. (2015) · Angewandte Chemie · doi:10.1002/ange.201506038 · Cited by 20

Tea tree oil nanoliposomes: optimization, characterization, and antibacterial activity against Escherichia coli in vitro and in vivo

Bo, R., Zhan, Y., Wei, S., Xu, S., Huang, Y., Liu, M., & Li, J. (2022) · Poultry Science · doi:10.1016/j.psj.2022.102238 · Cited by 20

Novel paradigms of innate immune sensing of viral infections

Hare, D. N., & Mossman, K. L. (2013) · Cytokine · doi:10.1016/j.cyto.2013.06.001 · Cited by 19

Only IL‐1β release is inflammasome‐dependent upon ultraviolet B irradiation although IL‐18 is also secreted

Korhonen, E., Piippo, N., Hytti, M., Hyttinen, J. M. T., Kaarniranta, K., & Kauppinen, A. (2020) · The FASEB Journal · doi:10.1096/fj.201902355rr · Cited by 21

Human Immunity AgainstCampylobacterInfection

Hameed, A. (2019) · Immune Network · doi:10.4110/in.2019.19.e38 · Cited by 20

Activation and evasion of inflammasomes during viral and microbial infection

Ren, D., Ye, X., Chen, R., Jia, X., He, X., Tao, J., Jin, T., Wu, S., & Zhang, H. (2025) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-025-05575-2 · Cited by 22

Immunomodulatory Effects of Selected Non-Nutritive Bioactive Compounds and Their Role in Optimal Nutrition

Napiórkowska-Baran, K., Treichel, P., Dardzińska, A., Majcherczak, A., Pilichowicz, A., Szota, M., Szymczak, B., Alska, E., Przybyszewska, J., & Bartuzi, Z. (2025) · Current Issues in Molecular Biology · doi:10.3390/cimb47020089 · Cited by 22

Inflammasomes: a preclinical assessment of targeting in atherosclerosis

Stitham, J., Rodríguez-Vélez, A., Zhang, X., Jeong, S., & Razani, B. (2020) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2020.1795831 · Cited by 20

Sedating Mechanically Ventilated COVID-19 Patients with Volatile Anesthetics: Insights on the Last-Minute Potential Weapons

Suleiman, A., Qaswal, A. B., Alnouti, M., Yousef, M., Suleiman, B., Jarbeh, M. E., Alshawabkeh, G., Bsisu, I., Santarisi, A., & Ababneh, M. (2021) · Scientia Pharmaceutica · doi:10.3390/scipharm89010006 · Cited by 19

Interaction Between Autophagy and Porphyromonas gingivalis-Induced Inflammation

Kang, S., Dai, A., Wang, H., & Ding, P. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.892610 · Cited by 20

New Potentiality of Bioactive Substances: Regulating the NLRP3 Inflammasome in Autoimmune Diseases

Chen, B., Wang, Y., & Chen, G. (2023) · Nutrients · doi:10.3390/nu15214584 · Cited by 19

Clotrimazole ameliorates chronic mild stress-induced depressive-like behavior in rats; crosstalk between the HPA, NLRP3 inflammasome, and Wnt/β-catenin pathways

Fawzi, S. F., Michel, H. E., Menze, E. T., Tadros, M. G., & George, M. Y. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.111354 · Cited by 23

Balanced regulation of ROS production and inflammasome activation in preventing early development of colorectal cancer

Li, L., Xu, T., & Qi, X. (2024) · Immunological Reviews · doi:10.1111/imr.13417 · Cited by 26

The Canonical Inflammasome: A Macromolecular Complex Driving Inflammation

Monie, T. P. (2017) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-3-319-46503-6_2 · Cited by 19

Processing and secretion of guanylate binding protein‐1 depend on inflammatory caspase activity

Naschberger, E., Geißdörfer, W., Bogdan, C., Tripal, P., Kremmer, E., Stürzl, M., & Britzen‐Laurent, N. (2017) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.13116 · Cited by 19

The Human-Specific STING Agonist G10 Activates Type I Interferon and the NLRP3 Inflammasome in Porcine Cells

Ming, S., Zeng, L., Guo, Y.-K., Zhang, S., Li, G., Ma, Y.-X., Zhai, Y.-Y., Chang, W.-R., Yang, L., Wang, J., et al. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.575818 · Cited by 19

Clustering of NLRP3 induced by membrane or protein scaffolds promotes inflammasome assembly

Boršić, E., Ramuta, T. Ž., Orehek, S., Kreft, M. E., Geyer, M., Jerala, R., & Hafner‐Bratkovič, I. (2025) · Nature Communications · doi:10.1038/s41467-025-60277-4 · Cited by 21

Decreased NLRP3 inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection

Cho, S. J., Plataki, M. E., Mitzel, D., Lowry, G., Rooney, K. T., & Stout-Delgado, H. W. (2017) · Experimental Gerontology · doi:10.1016/j.exger.2017.11.010 · Cited by 18

Dysregulated inflammasome activity in intestinal inflammation – Insights from patients with very early onset IBD

Illig, D., & Kotlarz, D. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1027289 · Cited by 17

NLRP3 ‐directed antisense oligonucleotides reduce microglial immunoactivities in vitro

Braatz, C., Komes, M. P., Ravichandran, K. A., de Fragas, M. G., Griep, A., Schwartz, S., McManus, R. M., & Heneka, M. T. (2023) · Journal of Neurochemistry · doi:10.1111/jnc.15778 · Cited by 20

Involvement of Hsp90 in NLRP3 inflammasome activation in the failing heart following myocardial infarction in rats

Marunouchi, T., Iguchi, A., Shindo, A., Shimbo, N., Yano, E., & Tanonaka, K. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2023.115547 · Cited by 17

Leptospira interrogans infection leads to IL-1β and IL-18 secretion from a human macrophage cell line through reactive oxygen species and cathepsin B mediated-NLRP3 inflammasome activation

Li, S., Wang, M., Ojcius, D. M., BiJun, Z., Hu, W., Liu, Y., Ma, Q., Tang, G., Wang, D., & Yan, J. (2018) · Microbes and Infection · doi:10.1016/j.micinf.2018.01.010 · Cited by 19

Inflammasome-Independent NALP3 Contributes to High-Salt Induced Endothelial Dysfunction

Fu, H., Chen, J., Lu, W., Jiang, Y., Wang, Y.-Y., Li, D., & Shen, F. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00968 · Cited by 18

Contribution of the inflammasomes to autoinflammatory diseases and recent mouse models as research tools

Heymann, M. C., & Rösen‐Wolff, A. (2013) · Clinical Immunology · doi:10.1016/j.clim.2013.01.006 · Cited by 20

Recent Developments in Immune Activation by Uric Acid Crystals

Ng, G., Chau, E. M. T., & Shi, Y. (2010) · Archivum Immunologiae et Therapiae Experimentalis · doi:10.1007/s00005-010-0082-1 · Cited by 18

Protein-bound polysaccharide-K induces IL-1β via TLR2 and NLRP3 inflammasome activation

Yang, Y., Inatsuka, C., Gad, E. A., Disis, M. L., Standish, L. J., Pugh, N. D., Pasco, D. S., & Lu, H. (2013) · Innate Immunity · doi:10.1177/1753425913513814 · Cited by 18

Interleukin-1β Processing Is Dependent on a Calcium-mediated Interaction with Calmodulin

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Application of immobilized ATP to the study of NLRP inflammasomes

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