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Cited by 671

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

The Challenge of Treating Biofilm-associated Bacterial Infections

del Pozo, J L, Patel, R·2007·Clinical Pharmacology & Therapeutics

Abstract

Biofilm formation is a crucial step in the pathogenesis of many subacute and chronic bacterial infections, including foreign body-related infections. Biofilms are difficult to eradicate with conventional antimicrobial agents. Bacterial biofilms have several potential antimicrobial resistance mechanisms. Antimicrobial resistance mechanisms may act concurrently, and in some cases, synergistically. Persister cells play a major role in the tolerance of biofilm bacteria to antimicrobial agents. Understanding the mechanisms involved in biofilm-associated antimicrobial resistance is key to development of new therapeutic strategies.

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Metadata

Authors
del Pozo, J. L., & Patel, R.
Venue
Clinical Pharmacology & Therapeutics
Publisher
Wiley
Published
2007-05-30
Volume
82
Issue
2
Pages
204-209
ISSN
  • 0009-9236 (ISSN-L)
  • 1532-6535
OpenAlex
W1997520863
Cited by
671
References
1
FWCI
7.30
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Challenge of Treating Biofilm-associated Bacterial Infections. https://app.cochat.ai/papers/10.1038/sj.clpt.6100247
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del Pozo, J. L., & Patel, R. (2007). The Challenge of Treating Biofilm-associated Bacterial Infections. Clinical Pharmacology & Therapeutics. https://doi.org/10.1038/sj.clpt.6100247

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.