The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.
Moderate alcohol consumption reduces plasma C-reactive protein and fibrinogen levels; a randomized, diet-controlled intervention study
Abstract
Objective To evaluate the effect of moderate alcohol consumption on the acute phase proteins C-reactive protein and fibrinogen.Design Randomized, diet-controlled, cross-over study.Setting The study was performed at TNO Nutrition and Food Research, Zeist, The Netherlands.Subjects Ten middle-aged men and 10 postmenopausal women, all apparently healthy, non-smoking and moderate alcohol drinkers, were included. One women dropped out because of a treatment-unrelated cause. The remaining 19 subjects finished the experiment successfully.Interventions Men consumed four glasses and women consumed three glasses of beer or no-alcohol beer (control) with evening dinner during two successive periods of 3 weeks. The total diet was supplied to the subjects and had essentially the same composition during these 6 weeks. Before each treatment there was a 1 week washout period to compensate for possible carry-over effects.Results Plasma C-reactive protein and fibrinogen levels were decreased by 35% (P=0.02) and 12.4% (P< or =0.001), respectively, after 3 weeks' consumption of beer, as compared to no-alcohol beer consumption.Conclusions Moderate alcohol consumption significantly decreased plasma C-reactive protein and fibrinogen levels. An anti-inflammatory action of alcohol may help explain the link between moderate alcohol consumption and lower cardiovascular disease risk.Sponsorship Dutch Foundation for Alcohol Research (SAR).
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“The health benefits of long-term regular exercise are ascribed to the anti-inflammatory response elicited by an acute bout of exercise, which is partly mediated by muscle-derived IL-6.”
From Dietary factors and low-grade inflammation in relation to overweight and obesity (2011) · cites this paper as [207]
In the citing paper
“(1) Contracting skeletal muscle is a major source of circulating IL-6 in response to acute exercise.”
From Dietary factors and low-grade inflammation in relation to overweight and obesity (2011) · cites this paper as [207]
Citations
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Fihn, S. D., Gardin, J. M., Abrams, J., Berra, K., Blankenship, J. C., Dallas, A. P., Douglas, P. S., Foody, J. M., Gerber, T. C., Hinderliter, A. L., et al. (2012) · Circulation · doi:10.1161/cir.0b013e3182776f83 · Cited by 2,418
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The relation between different dimensions of alcohol consumption and burden of disease: an overview
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Dietary factors and low-grade inflammation in relation to overweight and obesity
Calder, P. C., Ahluwalia, N., Brouns, F., Buetler, T., Clement, K., Cunningham, K., Esposito, K., Jönsson, L. S., Kolb, H., Lansink, M., et al. (2011) · British Journal of Nutrition · doi:10.1017/s0007114511005460 · Cited by 1,098
Diet-quality scores and plasma concentrations of markers of inflammation and endothelial dysfunction
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Metadata
- Authors
- Sierksma, A., van der Gaag, M., Kluft, C., & Hendriks, H.
- Affiliations
- Netherlands Organisation for Applied Scientific Research (NL)
- Corresponding author
- Hendriks, HFJ
- ORCID
- Venue
- European Journal of Clinical Nutrition
- Published
- 2002-11-01
- Volume
- 56
- Issue
- 11
- Pages
- 1130-1136
- ISSN
- 0954-3007 (ISSN-L)
- 1476-5640
- OpenAlex
- W2076812730
- Cited by
- 231
- References
- 33
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 4 · 2023: 9 · 2022: 7 · 2021: 8 · 2020: 13 · 2019: 10 · 2018: 6 · 2017: 7 · 2016: 4 · 2015: 6 · 2014: 6 · 2013: 6 · 2012: 16
- FWCI
- 10.45
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- TNO Repository (submittedVersion)
- Repository hosted by TU Delft Library (TU Delft) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Hematology › Blood properties and coagulation
- Keywords
- moderate drinking, beer, C-reactive protein, fibrinogen, acute phase proteins, cardiovascular risk, postmenopausal women, middle-aged men, controlled diet
- MeSH terms
- Alcohol Drinking, Beer, C-Reactive Protein, Cardiovascular Diseases, Diet, Female, Fibrinogen, Humans, Cholesterol, HDL, Liver, Male, Middle Aged, Triglycerides, Postmenopause, Cross-Over Studies
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