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HDAC inhibition improves autophagic and lysosomal function to prevent loss of subcutaneous fat in a mouse model of Cockayne syndrome

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p38 MAPK- and Akt-mediated p300 phosphorylation regulates its degradation to facilitate nucleotide excision repair

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Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD + signaling

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Cockayne Syndrome group B protein stimulates NEIL2 DNA glycosylase activity

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Deletion of 5′ sequences of the CSB gene provides insight into the pathophysiology of Cockayne syndrome

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UVB Induces a Genome-Wide Acting Negative Regulatory Mechanism That Operates at the Level of Transcription Initiation in Human Cells

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Mechanistic insights into the regulation of transcription and transcription-coupled DNA repair by Cockayne syndrome protein B

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Truncated Cockayne Syndrome B Protein Represses Elongation by RNA Polymerase I

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Traveling Rocky Roads: The Consequences of Transcription-Blocking DNA Lesions on RNA Polymerase II

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Etoposide-induced DNA damage affects multiple cellular pathways in addition to DNA damage response

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Conceptual developments in the causes of Cockayne syndrome

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XPD mutations in trichothiodystrophy hamper collagen VI expression and reveal a role of TFIIH in transcription derepression

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The Cockayne syndrome group A and B proteins are part of a ubiquitin–proteasome degradation complex regulating cell division

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A possible cranio-oro-facial phenotype in Cockayne syndrome

Bloch‐Zupan, A., Rousseaux, M., Laugel-Haushalter, V., Schmittbuhl, M., Mathis, R., Desforges, E., Koob, M., Zaloszyc, A., Dollfus, H., & Laugel, V. (2013) · Orphanet Journal of Rare Diseases · doi:10.1186/1750-1172-8-9 · Cited by 28

Transcription-coupled repair and the transcriptional response to UV-Irradiation

Gaul, L., & Svejstrup, J. Q. (2021) · DNA repair · doi:10.1016/j.dnarep.2021.103208 · Cited by 22

Repair of oxidatively generated DNA damage in Cockayne syndrome

Khobta, A., & Epe, B. (2013) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2013.03.001 · Cited by 23

Defective transcription of ATF3 responsive genes, a marker for Cockayne Syndrome

Epanchintsev, A., Rauschendorf, M., Costanzo, F., Calmels, N., Obringer, C., Sarasin, A. R., Coin, F., Laugel, V., & Egly, J. (2020) · Scientific Reports · doi:10.1038/s41598-020-57999-4 · Cited by 23

The molecular basis of chromatin dynamics during nucleotide excision repairThis paper is one of a selection of papers published in this Special Issue, entitled 29th Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal’s usual peer review process.

Zhang, L., Jones, K. L., & Gong, F. (2009) · Biochemistry and Cell Biology · doi:10.1139/o08-101 · Cited by 22

The current evidence for defective repair of oxidatively damaged DNA in Cockayne syndrome

Fròsina, G. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.04.001 · Cited by 22

Transcription Blockage by DNA Damage in Nucleotide Excision Repair-Related Neurological Dysfunctions

Kajitani, G. S., Nascimento, L. L. D. S., Neves, M. R. D. C., Leandro, G. D. S., Garcia, C. C. M., & Menck, C. F. M. (2021) · Seminars in Cell & Developmental Biology · doi:10.1016/j.semcdb.2020.10.009 · Cited by 22

Cockayne Syndrome Group B (CSB): The Regulatory Framework Governing the Multifunctional Protein and Its Plausible Role in Cancer

Spyropoulou, Z., Papaspyropoulos, A., Lаgopati, N., Myrianthopoulos, V., Georgakilas, A. G., Fousteri, M. I., Kotsinas, A., & Gorgoulis, V. G. (2021) · Cells · doi:10.3390/cells10040866 · Cited by 20

Cockayne syndrome B protein regulates recruitment of the Elongin A ubiquitin ligase to sites of DNA damage

Weems, J. C., Slaughter, B. D., Unruh, J. R., Boeing, S., Hall, S. M., McLaird, M. B., Yasukawa, T., Aso, T., Svejstrup, J. Q., Conaway, J. W., et al. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.c117.777946 · Cited by 21

The Peroxisome Proliferator WY-14,643 Promotes Hepatocarcinogenesis Caused by Endogenously Generated Oxidative DNA Base Modifications in Repair-Deficient Csbm/m/Ogg1−/− Mice

Trapp, C., Schwarz, M., & Epe, B. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-0335 · Cited by 21

Impaired Repair of Ionizing Radiation-Induced DNA Damage in Cockayne Syndrome Cells

Cramers, P., Verhoeven, E. E. A., Filon, A. R., Rockx, D., Santos, S. J., van der Leer, A. A., Kleinjans, J. C. S., van Zeeland, A. A., & Mullenders, L. H. F. (2011) · Radiation Research · doi:10.1667/rr1972.1 · Cited by 21

Mouse CSB protein is important for gene expression in the presence of a single-strand break in the non-transcribed DNA strand

Khobta, A., Lingg, T., Schulz, I., Warken, D., Kitsera, N., & Epe, B. (2010) · DNA repair · doi:10.1016/j.dnarep.2010.06.011 · Cited by 19

UVC inhibits HIF-1α protein translation by a DNA damage- and topoisomerase I-independent pathway

Rapisarda, A., & Melillo, G. (2007) · Oncogene · doi:10.1038/sj.onc.1210489 · Cited by 18

E2F1 and p53 Transcription Factors as Accessory Factors for Nucleotide Excision Repair

Vélez-Cruz, R., & Johnson, D. G. (2012) · International Journal of Molecular Sciences · doi:10.3390/ijms131013554 · Cited by 15

Molecular basis of chromatin remodeling by Rhp26, a yeast CSB ortholog

Wang, W., Xu, J., Limbo, O., Fei, J., Kassavetis, G. A., Chong, J. P. C., Kadonaga, J. T., Russell, P. R., Li, B., & Wang, D. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1818163116 · Cited by 15

Mechanisms of transcription-coupled repair and DNA damage surveillance in health and disease

van Sluis, M., Gonzalo-Hansen, C., Li, Q., Lans, H., Wang, D., & Marteijn, J. A. F. (2025) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-025-00915-3 · Cited by 21

CS proteins and ubiquitination: orchestrating DNA repair with transcription and cell division

Costanzo, F., Paccosi, E., Proietti‐De‐Santis, L., & Egly, J. (2024) · Trends in Cell Biology · doi:10.1016/j.tcb.2024.06.002 · Cited by 14

Transcription-coupled repair of DNA–protein crosslinks

Carnie, C. J., Jackson, S. P., & Stingele, J. (2024) · Trends in Cell Biology · doi:10.1016/j.tcb.2024.11.003 · Cited by 18

Testicular Nuclear Receptor 4 (TR4) Regulates UV Light-induced Responses via Cockayne Syndrome B Protein-mediated Transcription-coupled DNA Repair*

Liu, S., Yan, S.-J., Lee, Y.-F., Liu, N.-C., Ting, H., Li, G.-H., Wu, Q., Chen, L., & Chang, C. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.259523 · Cited by 13

Transcription factors that influence RNA polymerases I and II: To what extent is mechanism of action conserved?

Zhang, Y., Najmi, S. M., & Schneider, D. A. (2016) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2016.10.010 · Cited by 14

Transcription-Coupled Repair and Its Defect in Cockayne Syndrome

Ahmad, S. I. (2009) · CRC Press eBooks · doi:10.1201/9781498712705-8

Regulatory interplay of Cockayne syndrome B ATPase and stress-response gene ATF3 following genotoxic stress

Kristensen, U., Epanchintsev, A., Rauschendorf, M., Laugel, V., Stevnsner, T., Bohr, V. A., Coin, F., & Egly, J. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1220071110 · Cited by 63

UV-induced inhibition of transcription involves repression of transcription initiation and phosphorylation of RNA polymerase II

Rockx, D., Mason, R. S., van Hoffen, A., Barton, M. C., Citterio, E., Bregman, D. B., van Zeeland, A. A., Vrieling, H., & Mullenders, L. H. F. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.180169797 · Cited by 203

Cockayne syndrome B protein is implicated in transcription and associated chromatin dynamics in homeostatic and genotoxic conditions

Liakos, A., Ntakou‐Zamplara, K. Z., Angelova, N., Konstantopoulos, D., Synacheri, A., Spyropoulou, Z., Tsarmaklis, I. A., Korrou‐Karava, D., Nikolopoulos, G., Lavigne, M. D., et al. (2024) · Aging Cell · doi:10.1111/acel.14341 · Cited by 1

Cockayne’s Syndrome A and B Proteins Regulate Transcription Arrest after Genotoxic Stress by Promoting ATF3 Degradation

Epanchintsev, A., Costanzo, F., Rauschendorf, M., Caputo, M., Ye, T., Donnio, L., Proietti‐De‐Santis, L., Coin, F., Laugel, V., & Egly, J. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.11.009 · Cited by 104