Cited by 106Plant Virus Research StudiesPlant and Fungal Interactions ResearchPlant Molecular Biology Research

Viroids: an Ariadne's thread into the RNA labyrinth

Open access
Daròs, José‐Antonio, Elena, Santiago F, Flores, Ricardo·2006·The EMBO Reports

Abstract

Viroids are structurally, functionally and evolutionarily different from viruses. Despite their small, non-protein-encoding, single-stranded circular RNA genome, viroids can infect higher plants and cause certain diseases. Members of the two viroid families, Pospiviroidae and Avsunviroidae, have evolved to usurp the transcriptional machinery of their host nuclei and chloroplasts, respectively, in which replication proceeds through a rolling-circle mechanism involving RNA polymerization, cleavage and ligation. Remarkably, viroids subvert certain DNA-dependent RNA polymerases to transcribe RNA templates, and, in the family Avsunviroidae, post-transcriptional cleavage is catalysed by hammerhead ribozymes. Viroids are models for studying RNA evolution and for analysing RNA transport in plants, because they can move intracellularly, intercellularly through plasmodesmata and to distal parts of the plant through the vascular system. Viroids elicit RNA-silencing phenomena, which might mediate some of their biological properties, including pathogenesis. As some viroids behave as catalytic RNAs, they are regarded as remnants of the RNA world.

Integrity signals

Registry

Crossref · 10.1038/sj.embor.7400706

Cites

61 of 61 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Daròs, J., Elena, S. F., & Flores, R.
Affiliations
Instituto de Biología Molecular y Celular de Plantas (ES)
Venue
The EMBO Reports
Published
2006-06-01
Volume
7
Issue
6
Pages
593-598
ISSN
  • 1469-221X (ISSN-L)
  • 1469-3178
OpenAlex
W2053028162
Cited by
106
References
61
Citations by year
2024: 3 · 2023: 4 · 2022: 6 · 2021: 5 · 2020: 2 · 2019: 1 · 2018: 2 · 2017: 2 · 2016: 4 · 2015: 5 · 2014: 5 · 2013: 2 · 2012: 7
FWCI
1.05
Type
journal article
Language
en
Open access
Locations
  • EMBO Reports (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
Generalitat Valenciana
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Virus Research Studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Plant and Fungal Interactions Research
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
Keywords
viroids, Pospiviroidae, Avsunviroidae, plant viroid disease, rolling circle replication, RNA-dependent RNA polymerase, hammerhead ribozyme, RNA transport, plasmodesmata, RNA silencing, RNA evolution, RNA world, chloroplast replication, plant pathogenesis
MeSH terms
Base Sequence, Models, Biological, Models, Genetic, Molecular Sequence Data, Plant Viruses, RNA Processing, Post-Transcriptional, RNA, Viral, Viroids, Virus Replication, RNA, Catalytic, Evolution, Molecular, Gene Silencing, RNA Interference

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review