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Cited by 276

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Different Polycomb group complexes regulate common target genes in Arabidopsis

Open access
Makarevich, Grigory, Leroy, Olivier, Akinci, Umut, Schubert, Daniel, Clarenz, Oliver, Goodrich, Justin, Grossniklaus, Ueli, Köhler, Claudia·2006·EMBO reports

Abstract

Polycomb group (PcG) proteins convey epigenetic inheritance of repressed transcriptional states. Although the mechanism of the action of PcG is not completely understood, methylation of histone H3 lysine 27 (H3K27) is important in establishing PcG‐mediated transcriptional repression. We show that the plant PcG target gene PHERES1 is regulated by histone trimethylation on H3K27 residues mediated by at least two different PcG complexes in plants, containing the SET domain proteins MEDEA or CURLY LEAF/SWINGER. Furthermore, we identify FUSCA3 as a potential PcG target gene and show that FUSCA3 is regulated by MEDEA and CURLY LEAF/SWINGER. We propose that different PcG complexes regulate a common set of target genes during the different stages of plant development.

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Metadata

Authors
Makarevich, G., Leroy, O., Akinci, U., Schubert, D., Clarenz, O., Goodrich, J., Grossniklaus, U., & Köhler, C.
Venue
EMBO reports
Published
2006-07-28
Volume
7
Issue
9
Pages
947-952
ISSN
  • 1469-221X (ISSN-L)
  • 1469-3178
OpenAlex
W2160477539
Cited by
276
References
1
FWCI
10.56
Type
journal article
Language
en
Open access
green

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Makarevich, G., Leroy, O., Akinci, U., Schubert, D., Clarenz, O., Goodrich, J., Grossniklaus, U., & Köhler, C. (2006). Different Polycomb group complexes regulate common target genes in Arabidopsis. EMBO reports. https://doi.org/10.1038/sj.embor.7400760

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