The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Parallel analysis of transcript and metabolic profiles: a new approach in systems biology
Open accessAbstract
The past few years in the medical and biological sciences have been characterized by the advent of systems biology. However, despite the well‐known connectivity between the molecules described by transcriptomic, proteomic and metabolomic approaches, few studies have tried to correlate parameters across the various levels of systemic description. When comparing the discriminatory power of metabolic and RNA profiling to distinguish between different potato tuber systems, using the techniques described here suggests that metabolic profiling has a higher resolution than expression profiling. When applying pairwise transcript–metabolite correlation analyses, 571 of the 26,616 possible pairs showed significant correlation, most of which was novel and included several strong correlations to nutritionally important metabolites. We believe this approach to be of high potential value in the identification of candidate genes for modifying the metabolite content of biological systems.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
Initiative, T. A. G. (2000) · Nature · doi:10.1038/35048692 · Cited by 9,301
A N EW A PPROACH TO D ECODING L IFE : Systems Biology
Ideker, T., Galitski, T., & Hood, L. (2001) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.2.1.343 · Cited by 1,664
Cited by
Gut microorganisms, mammalian metabolism and personalized health care
Nicholson, J. K., Holmes, E., & Wilson, I. D. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1152 · Cited by 945
Metabolomics-assisted breeding: a viable option for crop improvement?
Fernie, A. R., & Schauer, N. (2009) · Trends in Genetics · doi:10.1016/j.tig.2008.10.010 · Cited by 550
Self-citationMetabolomics and systems biology: making sense of the soup
KELL, D. (2004) · Current Opinion in Microbiology · doi:10.1016/j.mib.2004.04.012 · Cited by 529
Decoding genes with coexpression networks and metabolomics – ‘majority report by precogs’
Saito, K., Hirai, M. Y., & Yonekura-Sakakibara, K. (2008) · Trends in Plant Science · doi:10.1016/j.tplants.2007.10.006 · Cited by 327
Metabolite annotations based on the integration of mass spectral information
Iijima, Y., Nakamura, Y., Ogata, Y., Tanaka, K., Sakurai, N., Suda, K., Suzuki, T., Suzuki, H., Okazaki, K., Kitayama, M., et al. (2008) · The Plant Journal · doi:10.1111/j.1365-313x.2008.03434.x · Cited by 283
Metadata
- Authors
- Urbanczyk‐Wochniak, E., Luedemann, A., Kopka, J., Selbig, J., Roessner‐Tunali, U., Willmitzer, L., & Fernie, A. R.
- Venue
- EMBO reports
- Published
- 2003-09-12
- Volume
- 4
- Issue
- 10
- Pages
- 989-993
- ISSN
- 1469-221X (ISSN-L)
- 1469-3178
- OpenAlex
- W2137591509
- Cited by
- 324
- References
- 2
- FWCI
- 8.04
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Parallel analysis of transcript and metabolic profiles: a new approach in systems biology. https://app.cochat.ai/papers/10.1038/sj.embor.embor944
- The paper
- Urbanczyk‐Wochniak, E., Luedemann, A., Kopka, J., Selbig, J., Roessner‐Tunali, U., Willmitzer, L., & Fernie, A. R. (2003). Parallel analysis of transcript and metabolic profiles: a new approach in systems biology. EMBO reports. https://doi.org/10.1038/sj.embor.embor944
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
