Protective Role of Reactive Astrocytes in Brain Ischemia

Identification of a Neural Stem Cell in the Adult Mammalian Central Nervous System

Johansson, C. B., Momma, S., Clarke, D. L., Risling, M., Lendahl, U., & Frisén, J. (1999) · Cell · doi:10.1016/s0092-8674(00)80956-3 · Cited by 1,875

Reactive astrocytes: cellular and molecular cues to biological function

Ridet, J., Privat, A., Malhotra, S. K., & Gage, F. H. (1997) · Trends in Neurosciences · doi:10.1016/s0166-2236(97)01139-9 · Cited by 1,766

Localization of neuronal and glial glutamate transporters

Rothstein, J. D., Martin, L. J., Levey, A. I., Dykes‐Hoberg, M., Jin, L., Wu, D. M., Nash, N. R., & Kuncl, R. W. (1994) · Neuron · doi:10.1016/0896-6273(94)90038-8 · Cited by 1,703

Reactive Astrocytes Protect Tissue and Preserve Function after Spinal Cord Injury

Faulkner, J. R., Herrmann, J. E., Woo, M. J., Tansey, K. E., Doan, N., & Sofroniew, M. V. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.3547-03.2004 · Cited by 1,652

Molecular profile of reactive astrocytes—Implications for their role in neurologic disease

Eddleston, M., & Mucke, L. (1993) · Neuroscience · doi:10.1016/0306-4522(93)90380-x · Cited by 1,441

Leukocyte Infiltration, Neuronal Degeneration, and Neurite Outgrowth after Ablation of Scar-Forming, Reactive Astrocytes in Adult Transgenic Mice

Bush, T. G., Puvanachandra, N., Horner, C. H., Polito, A., Ostenfeld, T., Svendsen, C. N., Mucke, L., Johnson, M. H., & Sofroniew, M. V. (1999) · Neuron · doi:10.1016/s0896-6273(00)80781-3 · Cited by 1,116

Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury

Okada, S., Nakamura, M., Katoh, H., Miyao, T., Shimazaki, T., Ishii, K., Yamane, J., Yoshimura, A., Iwamoto, Y., Toyama, Y., et al. (2006) · Nature Medicine · doi:10.1038/nm1425 · Cited by 991

Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator

Tsirka, S. E., Gualandris, A., Amaral, D. G., & Strickland, S. (1995) · Nature · doi:10.1038/377340a0 · Cited by 658

GFAP Is Necessary for the Integrity of CNS White Matter Architecture and Long-Term Maintenance of Myelination

Liedtke, W., Edelmann, W., Bieri, P. L., Chiu, F.-C., Cowan, N. J., Kucherlapati, R., & Raine, C. S. (1996) · Neuron · doi:10.1016/s0896-6273(00)80194-4 · Cited by 538

Gap-junction-mediated propagation and amplification of cell injury

Lin, J. H.-C., Weigel, H., Cotrina, M. L., Liu, S., Bueno, E., Hansen, A. J., Hansen, T. W., Goldman, S. A., & Nedergaard, M. (1998) · Nature Neuroscience · doi:10.1038/2210 · Cited by 481

Response of Hippocampal Neurons and Glial Cells to Alternating Magnetic Field in Gerbils Submitted to Global Cerebral Ischemia

Balind, S. R., Selaković, V., Manojlović‐Stojanoski, M., Radenović, L., Prolić, Z., & Petković, B. B. (2012) · Neurotoxicity Research · doi:10.1007/s12640-012-9333-8 · Cited by 47

Glial Cells Drive Preconditioning-Induced Blood-Brain Barrier Protection

Gesuete, R., Orsini, F., Zanier, E. R., Albani, D., Deli, M. A., Bazzoni, G., & Simoni, M. G. D. (2011) · Stroke · doi:10.1161/strokeaha.110.603266 · Cited by 46

Cell-based therapy for ischemic stroke

Zhang, J., & Chopp, M. (2013) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2013.804507 · Cited by 48

Axonal Regeneration after Sciatic Nerve Lesion Is Delayed but Complete in GFAP- and Vimentin-Deficient Mice

Berg, A., Zelano, J., Pekna, M., Wilhelmsson, U., Pekny, M., & Cullheim, S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0079395 · Cited by 47

Regulatory T lymphocytes as a therapy for ischemic stroke

Wang, M., Thomson, A., Yu, F., Hazra, R., Junagade, A., & Hu, X.-M. (2022) · Seminars in Immunopathology · doi:10.1007/s00281-022-00975-z · Cited by 40

Proliferative reactive gliosis is compatible with glial metabolic support and neuronal function

Vázquez-Chona, F., Swan, A. G., Ferrell, W. D., Jiang, L., Baehr, W., Chien, W., Fero, M. L., Marc, R. E., & Levine, E. M. (2011) · BMC Neuroscience · doi:10.1186/1471-2202-12-98 · Cited by 46

Neuronal deficiency of HIF prolyl 4-hydroxylase 2 in mice improves ischemic stroke recovery in an HIF dependent manner

Li, L., Saliba, P., Reischl, S., Marti, H. H., & Kunze, R. (2016) · Neurobiology of Disease · doi:10.1016/j.nbd.2016.03.018 · Cited by 45

Role of astrocyte activation in fine particulate matter-enhancement of existing ischemic stroke in Sprague-Dawley male rats

Zhang, C., Meng, Q., Zhang, X., Wu, S., Wang, S., Chen, R., & Li, X. (2016) · Journal of Toxicology and Environmental Health · doi:10.1080/15287394.2016.1176615 · Cited by 45

Complement Peptide C3a Promotes Astrocyte Survival in Response to Ischemic Stress

Shinjyo, N., de Pablo, Y., Pekny, M., & Pekna, M. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9204-4 · Cited by 48

Intermediate filament transcription in astrocytes is repressed by proteasome inhibition

Middeldorp, J., Kamphuis, W., Sluijs, J. A., Achoui, D., Leenaars, C. H. C., Feenstra, M. G. P., van Tijn, P., Fischer, D. F., Berkers, C. R., Ovaa, H., et al. (2009) · The FASEB Journal · doi:10.1096/fj.08-127696 · Cited by 45

The role of reciprocal activation of cAbl and Mst1 in the Oxidative death of cultured astrocytes

Lee, S., Seo, B., Choi, E., & Koh, J. (2014) · Glia · doi:10.1002/glia.22631 · Cited by 44

High-fat diet feeding causes rapid, non-apoptotic cleavage of caspase-3 in astrocytes

Guyenet, S. J., Hồng, N. T., Hwang, B. H., Schwartz, M. W., Baskin, D. G., & Thaler, J. P. (2013) · Brain Research · doi:10.1016/j.brainres.2013.03.033 · Cited by 44

Ischemic stroke in neonatal and adult astrocytes

Revuelta, M., Elicegui, A., Moreno‐Cugnon, L., Bührer, C., Matheu, A., & Schmitz, T. (2019) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2019.111147 · Cited by 44

Neuroinflammatory Triangle Presenting Novel Pharmacological Targets for Ischemic Brain Injury

Shaheryar, Z. A., Khan, M. A., Adnan, C. S., Zaidi, A. A., Hänggi, D., & Muhammad, S. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.748663 · Cited by 46

Heterogeneity of Notch signaling in astrocytes and the effects of GFAP and vimentin deficiency

Lebkuechner, I., Wilhelmsson, U., Möllerström, E., Pekna, M., & Pekny, M. (2015) · Journal of Neurochemistry · doi:10.1111/jnc.13213 · Cited by 45

Phosphorylation of connexin 43 induced by traumatic brain injury promotes exosome release

Chen, W., Guo, Y., Yang, W., Chen, L., Ren, D., Wu, C., He, B., Zheng, P., & Tong, W. (2017) · Journal of Neurophysiology · doi:10.1152/jn.00654.2017 · Cited by 42

Proteomic Analysis of Rat Cerebral Cortex in the Subacute to Long-Term Phases of Focal Cerebral Ischemia-Reperfusion Injury

Wen, M., Jin, Y., Zhang, H., Sun, X., Kuai, Y., & Tan, W. (2019) · Journal of Proteome Research · doi:10.1021/acs.jproteome.9b00220 · Cited by 42

Prediction of Outcome After Endovascular Embolectomy in Anterior Circulation Stroke Using Biomarkers

Pujol-Calderón, F., Zetterberg, H., Portelius, E., Hendèn, P. L., Rentzos, A., Karlsson, J.-E., Höglund, K., Blennow, K., & Rosengren, L. (2021) · Translational Stroke Research · doi:10.1007/s12975-021-00905-5 · Cited by 42

Hypoxic postconditioning reduces microglial activation, astrocyte and caspase activity, and inflammatory markers after hypoxia–ischemia in the neonatal rat brain

Teo, J. D., Morris, M. J., & Jones, N. M. (2015) · Pediatric Research · doi:10.1038/pr.2015.47 · Cited by 41

The HIF-1 inhibitor YC-1 decreases reactive astrocyte formation in a rodent ischemia model.

Na, J., Na, J., Choi, W.-Y., Lee, M. C., Park, M., Choi, K., Lee, J.-K., Kim, K.-T., Park, J., & Kim, H.-S. (2015) · PubMed Central · Cited by 41

The cysteine residue of glial fibrillary acidic protein is a critical target for lipoxidation and required for efficient network organization

Viedma-Poyatos, Á., de Pablo, Y., Pekny, M., & Pérez‐Sala, D. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.04.007 · Cited by 41

CD36 deficiency reduces chronic BBB dysfunction and scar formation and improves activity, hedonic and memory deficits in ischemic stroke

Balkaya, M., Kim, I., Shakil, F., & Cho, S. (2020) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x20924099 · Cited by 41

Targeting Complement C3a Receptor to Improve Outcome After Ischemic Brain Injury

Pekna, M., Stokowska, A., & Pekny, M. (2021) · Neurochemical Research · doi:10.1007/s11064-021-03419-6 · Cited by 41

Baclofen facilitates sleep, neuroplasticity, and recovery after stroke in rats

Hodor, A., Palchykova, S., Baracchi, F., Noaín, D., & Bassetti, C. L. (2014) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.115 · Cited by 41

Stroke and Neurogenesis: Bridging Clinical Observations to New Mechanistic Insights from Animal Models

Passarelli, J. P., Nimjee, S. M., & Townsend, K. L. (2022) · Translational Stroke Research · doi:10.1007/s12975-022-01109-1 · Cited by 41

Ischemia Increases TREK-2 Channel Expression in Astrocytes: Relevance to Glutamate Clearance

Kucheryavykh, L. Y., Kucheryavykh, Y. V., Inyushin, M. Y., Шуба, Я. М., Sanabria, P., Cubano, L. A., Skatchkov, S. N., & Eaton, M. J. (2009) · The Open Neuroscience Journal · doi:10.2174/1874082000903010040 · Cited by 40

Hyperglycemia and high nitric oxide level induced oxidative stress in the brain and molecular alteration in the neurons and glial cells of laboratory mouse, Mus musculus

Richa, R., Yadawa, A. K., & Chaturvedi, C. M. (2016) · Neurochemistry International · doi:10.1016/j.neuint.2016.12.008 · Cited by 42

Regulatory T Cell in Stroke: A New Paradigm for Immune Regulation

Chen, S., Wu, H., Klebe, D. W., Hong, Y., Zhang, J., & Tang, J. (2013) · Clinical and Developmental Immunology · doi:10.1155/2013/689827 · Cited by 39

Transplantation of TAT-Bcl-xL-transduced neural precursor cells: Long-term neuroprotection after stroke

Doeppner, T. R., Aanbouri, M. E., Dietz, G. P. H., Weise, J., Schwarting, S., & Bähr, M. (2010) · Neurobiology of Disease · doi:10.1016/j.nbd.2010.05.033 · Cited by 39

The neglected co-star in the dementia drama: the putative roles of astrocytes in the pathogeneses of major neurocognitive disorders

Jo, W. K., Law, A. C. K., & Chung, S. K. (2014) · Molecular Psychiatry · doi:10.1038/mp.2013.171 · Cited by 40

Astrocytes and lysosomal storage diseases

Rao, K. V. R., & Kielian, T. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.05.061 · Cited by 42

Astrogliosis and glial scar in ischemic stroke - focused on mechanism and treatment

Chen, W., Su, G., Chai, M., An, Y., Song, J., & Zhang, Z. (2024) · Experimental Neurology · doi:10.1016/j.expneurol.2024.115131 · Cited by 40

Chronic daily cortical spreading depressions suppress spreading depression susceptibility

Sukhotinsky, I., Dileköz, E., Wang, Y., Qin, T., Eikermann‐Haerter, K., Waeber, C., & Ayata, C. (2011) · Cephalalgia · doi:10.1177/0333102411425865 · Cited by 37

The Neuroprotective Roles of Sonic Hedgehog Signaling Pathway in Ischemic Stroke

Liu, L., Zhao, B., Xiong, X., & Xia, Z. (2018) · Neurochemical Research · doi:10.1007/s11064-018-2645-1 · Cited by 38

Dexmedetomidine Protects Against Oxygen–Glucose Deprivation-Induced Injury Through Inducing Astrocytes Autophagy via TSC2/mTOR Pathway

Zhu, C. Y., Zhou, Q., Luo, C., & Chen, Y. (2019) · NeuroMolecular Medicine · doi:10.1007/s12017-019-08576-0 · Cited by 37

Anthocyanin Extracts from Black Soybean (Glycine max L.) Protect Human Glial Cells Against Oxygen-Glucose Deprivation by Promoting Autophagy

Kim, Y.-K., Yoon, H. H., Lee, Y.-D., Youn, D., Ha, T.-J., Kim, H.-S., & Lee, J. H. (2012) · Biomolecules & Therapeutics · doi:10.4062/biomolther.2012.20.1.068 · Cited by 37

Monocarboxylate transporter-dependent mechanism confers resistance to oxygen- and glucose-deprivation injury in astrocyte-neuron co-cultures

Gao, C., Zhou, L., Zhu, W., Wang, H., Wang, R., He, Y., & Li, Z. (2015) · Neuroscience Letters · doi:10.1016/j.neulet.2015.03.062 · Cited by 36

Scutellarin promotes microglia-mediated astrogliosis coupled with improved behavioral function in cerebral ischemia

Fang, M., Yuan, Y., Lu, J., Li, H. E., Zhao, M., Ling, E., & Wu, C. (2016) · Neurochemistry International · doi:10.1016/j.neuint.2016.04.007 · Cited by 36

Transplantation of Embryonic Neural Stem/Precursor Cells Overexpressing BM88/Cend1 Enhances the Generation of Neuronal Cells in the Injured Mouse Cortex

Makri, G., Lavdas, A. Α., Katsimpardi, L., Charneau, P., Thomaidou, D., & Matsas, R. (2009) · Stem Cells · doi:10.1002/stem.258 · Cited by 36

Oxidative and excitotoxic insults exert differential effects on spinal motoneurons and astrocytic glutamate transporters: Implications for the role of astrogliosis in amyotrophic lateral sclerosis

Zagami, C. J., Beart, P. M., Wallis, N., Nagley, P., & O’Shea, R. D. (2008) · Glia · doi:10.1002/glia.20739 · Cited by 36

The neuron-astrocyte-microglia triad in CA3 after chronic cerebral hypoperfusion in the rat: Protective effect of dipyridamole

Lana, D., Ugolini, F., Melani, A., Nosi, D., Pedata, F., & Giovannini, M. G. (2017) · Experimental Gerontology · doi:10.1016/j.exger.2017.06.006 · Cited by 36

Synemin is expressed in reactive astrocytes and Rosenthal fibers in Alexander disease

Pekny, T., Faiz, M., Wilhelmsson, U., Curtis, M. A., Matěj, R., Skalli, O., & Pekny, M. (2013) · Apmis · doi:10.1111/apm.12088 · Cited by 39

Exacerbation of Experimental Autoimmune Encephalomyelitis in the Absence of Breast Regression Protein 39/Chitinase 3-Like 1

Bonneh‐Barkay, D., Wang, G., LaFramboise, W. A., Wiley, C. A., & Bissel, S. J. (2012) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e31826eaee7 · Cited by 35

Modulation of Inflammatory Responses After Global Ischemia by Transplanted Umbilical Cord Matrix Stem Cells

Hirko, A. C., Dallasen, R., Jomura, S., & Xu, Y. (2008) · Stem Cells · doi:10.1634/stemcells.2008-0075 · Cited by 35

Phosphorylation of GFAP is Associated with Injury in the Neonatal Pig Hypoxic-Ischemic Brain

Sullivan, S. M., Sullivan, R., Miller, S. M., Ireland, Z., Bjorkman, S. T., Pow, D. V., & Colditz, P. B. (2012) · Neurochemical Research · doi:10.1007/s11064-012-0774-5 · Cited by 38

From Physiology to Pathology of Astrocytes: Highlighting Their Potential as Therapeutic Targets for CNS Injury

Yuan, Y., Liu, H., Dai, Z., He, C., Qin, S., & Su, Z. (2024) · Neuroscience Bulletin · doi:10.1007/s12264-024-01258-3 · Cited by 37

Astrocytic TRPV4 Channels and Their Role in Brain Ischemia

Turečková, J., Heřmanová, Z., Marchetti, V., & Anděrová, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087101 · Cited by 34

Functional recovery after delayed treatment of ischemic stroke with melanocortins is associated with overexpression of the activity-dependent gene Zif268

Giuliani, D., Ottani, A., Minutoli, L., Stefano, V. D., Galantucci, M., Bitto, A., Zaffe, D., Altavilla, D., Botticelli, A. R., Squadrito, F., et al. (2009) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2009.03.009 · Cited by 34

Short and Long-Term Analysis and Comparison of Neurodegeneration and Inflammatory Cell Response in the Ipsilateral and Contralateral Hemisphere of the Neonatal Mouse Brain after Hypoxia/Ischemia

Shrivastava, K., Chertoff, M., Llovera, G., Recasens, M., & Acarín, L. (2012) · Neurology Research International · doi:10.1155/2012/781512 · Cited by 33

Reversal of functional loss in a rat model of chronic intraocular pressure elevation

Liu, H., He, Z., Nguyen, C. T. O., Vingrys, A. J., & Bui, B. V. (2016) · Ophthalmic and Physiological Optics · doi:10.1111/opo.12331 · Cited by 33

Photothrombotic Stroke Induces Persistent Ipsilateral and Contralateral Astrogliosis in Key Cognitive Control Nuclei

Patience, M., Zouikr, I., Jones, K., Clarkson, A. N., Isgaard, J., Johnson, S. J., Walker, F. R., & Nilsson, M. (2014) · Neurochemical Research · doi:10.1007/s11064-014-1487-8 · Cited by 33

Ischemic–hypoxic mechanisms leading to hippocampal dysfunction as a consequence of status epilepticus

Lucchi, C., Vinet, J., Meletti, S., & Biagini, G. (2015) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2015.04.003 · Cited by 33

Temporal relationship between aquaporin-4 and glial fibrillary acidic protein in cerebellum of neonate and adult rats administered a BBB disrupting spider venom

Stávale, L. M., Soares, E. S., Mendonça, M. C. P., Irazusta, S. P., & Höfling, M. A. D. C. (2013) · Toxicon · doi:10.1016/j.toxicon.2013.01.026 · Cited by 32

Dual role of astrocytes in perinatal asphyxia injury and neuroprotection

Romero, J. I., Muñiz, J. A., Tornatore, T. L., Holubiec, M. I., González, J., Barreto, G. E., Guelman, L. R., Lillig, C. H., Blanco, E., & Capani, F. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.10.046 · Cited by 32

Astrocytes and ischemic tolerance

Hirayama, Y., & Koizumi, S. (2017) · Neuroscience Research · doi:10.1016/j.neures.2017.11.013 · Cited by 32

Capacity of astrocytes to promote axon growth in the injured mammalian central nervous system

Hemati-Gourabi, M., Cao, T., Romprey, M. K., & Chen, M. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.955598 · Cited by 32

Intermediate filaments of zebrafish retinal and optic nerve astrocytes and Müller glia: differential distribution of cytokeratin and GFAP

Koke, J. R., Mosier, A. L., & Garcia, D. (2010) · BMC Research Notes · doi:10.1186/1756-0500-3-50 · Cited by 32

Bone Marrow Stromal Cells Combined with Sodium Ferulate and n -Butylidenephthalide Promote the Effect of Therapeutic Angiogenesis via Advancing Astrocyte-Derived Trophic Factors after Ischemic Stroke

Zhang, Q., Chen, Z., Zhao, Y., Liu, B.-W., Liu, N., Ke, C., & Tan, H. (2016) · Cell Transplantation · doi:10.3727/096368916x693536 · Cited by 32

Chronic stress induced disruption of the peri-infarct neurovascular unit following experimentally induced photothrombotic stroke

Zhao, Z., Ong, L. K., Johnson, S. J., Nilsson, M., & Walker, F. R. (2017) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x17696100 · Cited by 31

Chemical preconditioning-induced reactive astrocytosis contributes to the reduction of post-ischemic edema through aquaporin-4 downregulation

Hoshi, A., Yamamoto, T., Shimizu, K., Sugiura, Y., & Ugawa, Y. (2010) · Experimental Neurology · doi:10.1016/j.expneurol.2010.09.016 · Cited by 31

Targeted Overexpression of Endothelin-1 in Astrocytes Leads to More Severe Cytotoxic Brain Edema and Higher Mortality

Yeung, P. K. K., Lo, A., Leung, J. W. C., Chung, S. S. M., & Chung, S. K. (2009) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2009.175 · Cited by 31

Characteristic Changes of Astrocyte and Microglia in Rat Striatum Induced by 3-NP and MCAO

Mu, S., Liu, B., OuYang, L., Zhan, M., Chen, S. X., Wu, J., Chen, J., Wei, X., Wang, W., Zhang, J., et al. (2015) · Neurochemical Research · doi:10.1007/s11064-015-1739-2 · Cited by 31

Tert-butylhydroquinone enhanced angiogenesis and astrocyte activation by activating nuclear factor-E2-related factor 2/heme oxygenase-1 after focal cerebral ischemia in mice

Chen, Y., Zhang, X., Yang, Y., Zhang, L., Cui, L., Zhang, C., Chen, R., Xie, Y., He, J., & He, W. (2019) · Microvascular Research · doi:10.1016/j.mvr.2019.103891 · Cited by 31

Secondary neurodegeneration following Stroke: what can blood biomarkers tell us?

Brunelli, S., Giannella, E., Bizzaglia, M., Angelis, D. D., & Sancesario, G. M. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1198216 · Cited by 30

Short general anaesthesia induces prolonged changes in gene expression in the mouse hippocampus

Pekny, T., Andersson, D., Wilhelmsson, U., Pekna, M., & Pekny, M. (2014) · Acta Anaesthesiologica Scandinavica · doi:10.1111/aas.12369 · Cited by 30

Insulin increases glutamate transporter GLT1 in cultured astrocytes

Ji, Y.-F., Xu, S., Zhu, J., Wang, X., & Shen, Y. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.01.105 · Cited by 30

Perspectives on the role of brain cellular players in cancer-associated brain metastasis: translational approach to understand molecular mechanism of tumor progression

Raza, M., Prasad, P., Gupta, P., Kumar, N., V, Sharma, T., Rana, M., Goldman, A. J., & Sehrawat, S. (2018) · Cancer and Metastasis Reviews · doi:10.1007/s10555-018-9766-5 · Cited by 29

Vimentin is required for normal accumulation of body fat

Wilhelmsson, U., Stillemark-Billton, P., Borén, J., & Pekny, M. (2019) · Biological Chemistry · doi:10.1515/hsz-2019-0170 · Cited by 30

Exocytosis in Astrocytes

Mielnicka, A., & Michaluk, P. (2021) · Biomolecules · doi:10.3390/biom11091367 · Cited by 31

Retinal functional alterations in mice lacking intermediate filament proteins glial fibrillary acidic protein and vimentin

Wunderlich, K. A., Tanimoto, N., Grosche, A., Zrenner, E., Pekny, M., Reichenbach, A., Seeliger, M. W., Pannicke, T., & Perez, M.-T. (2015) · The FASEB Journal · doi:10.1096/fj.15-272963 · Cited by 29

Focal Ischaemic Infarcts Expand Faster in Cerebellar Cortex than Cerebral Cortex in a Mouse Photothrombotic Stroke Model

Gorlamandala, N., Parmar, J., Craig, A. J., Power, J., Moorhouse, A. J., Krishnan, A. V., & Housley, G. D. (2018) · Translational Stroke Research · doi:10.1007/s12975-018-0615-1 · Cited by 29

Ferritin nanoconjugates guide trastuzumab brain delivery to promote an antitumor response in murine HER2 + breast cancer brain metastasis

Sevieri, M., Mazzucchelli, S., Barbieri, L., Garbujo, S., Carelli, S., Bonizzi, A., Rey, F., Recordati, C., Recchia, M., Allevi, R., et al. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.106934 · Cited by 28

Repetitive transcranial magnetic stimulation for stroke rehabilitation-potential therapy or misplaced hope?

Bates, K. A., & Rodger, J. (2015) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-130359 · Cited by 28

Inducible astrocytic glucose transporter-3 contributes to the enhanced storage of intracellular glycogen during reperfusion after ischemia

Iwabuchi, S., & Kawahara, K. (2011) · Neurochemistry International · doi:10.1016/j.neuint.2011.06.006 · Cited by 29

Astrocytic Cx 43 and Cx 40 in the mouse hippocampus during and after pilocarpine-induced status epilepticus

Wu, X.-L., Tang, Y.-C., Lu, Q.-Y., Xiao, X.-L., Song, T., & Tang, F. (2015) · Experimental Brain Research · doi:10.1007/s00221-015-4226-8 · Cited by 15

Corticosteroids and perinatal hypoxic-ischemic brain injury

Concepcion, K. R., & Zhang, L. (2018) · Drug Discovery Today · doi:10.1016/j.drudis.2018.05.019 · Cited by 28

Astrocytes in rare neurological conditions: Morphological and functional considerations

Ravi, K., Paidas, M. J., Saad, A. G., & Jayakumar, A. R. (2021) · The Journal of Comparative Neurology · doi:10.1002/cne.25118 · Cited by 28

Fibroblast growth factor 2 regulates astrocyte differentiation in a region‐specific manner in the hindbrain

Irmady, K., Zechel, S., & Unsicker, K. (2011) · Glia · doi:10.1002/glia.21141 · Cited by 27

Caspase‐11 mediates ischemia‐induced astrocyte death: Involvement of endoplasmic reticulum stress and C/EBP homologous protein

Fradejas‐Villar, N., Pastor, M. D., Burgos, M., Beyaert, R., Tranque, P., & Calvo, S. (2009) · Journal of Neuroscience Research · doi:10.1002/jnr.22280 · Cited by 27

Neuroprotective effect of Withania somnifera leaves extract nanoemulsion against penconazole-induced neurotoxicity in albino rats via modulating TGF-β1/Smad2 signaling pathway

Abomosallam, M., Hendam, B. M., Abdallah, A. A., Refaat, R., & El-Hak, H. N. G. (2024) · Inflammopharmacology · doi:10.1007/s10787-024-01461-8 · Cited by 28

Biochemical, histopathological and behavioral alterations caused by intrastriatal administration of quinolic acid to young rats

Pierozan, P., Fernandes, C. G., Dutra, M. F., Pandolfo, P., Ferreira, F. S., de Lima, B. O., Porciúncula, L. O., Wajner, M., & Pessoa‐Pureur, R. (2014) · FEBS Journal · doi:10.1111/febs.12762 · Cited by 27

Diverse functions and mechanisms of regulatory T cell in ischemic stroke

Wu, Y., Li, J., Shou, J., Zhang, W., & Chen, C. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113782 · Cited by 26

Hypoxic Preconditioning Differentially Affects GABAergic and Glutamatergic Neuronal Cells in the Injured Cerebellum of the Neonatal Rat

Benitez, S. G., Castro, A. E., Patterson, S. I., Muñoz, E. M., & Seltzer, A. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0102056 · Cited by 26

Acute Complement Inhibition Potentiates Neurorehabilitation and Enhances tPA-Mediated Neuroprotection

Alawieh, A. M., Andersen, M., Adkins, D. L., & Tomlinson, S. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.0111-18.2018 · Cited by 26

Stochastic cell-cycle entry and cell-state-dependent fate outputs of injury-reactivated tectal radial glia in zebrafish

Yu, S., & He, J. (2019) · eLife · doi:10.7554/elife.48660 · Cited by 26

Endogenous brain protection: What the cerebral transcriptome teaches us

Cox-Limpens, K. E. M., Gavilanes, A. W. D., Zimmermann, L. J. I., & Vles, J. S. H. (2014) · Brain Research · doi:10.1016/j.brainres.2014.04.001 · Cited by 25

Loss-of-function manipulations to identify roles of diverse glia and stromal cells during CNS scar formation

Wahane, S., & Sofroniew, M. V. (2021) · Cell and Tissue Research · doi:10.1007/s00441-021-03487-8 · Cited by 25

SC1/Hevin Identifies Early White Matter Injury After Ischemia and Intracerebral Hemorrhage in Young and Aged Rats

Lively, S. S., & Schlichter, L. C. (2012) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e318256901c · Cited by 25

Diabetes Inhibits Cerebral Ischemia-Induced Astrocyte Activation - an Observation in the Cingulate Cortex

Jing, L., Mai, L., Zhang, J.-Z., Wang, J., Chang, Y., Dong, J., Guo, F., & Li, P. A. (2013) · International Journal of Biological Sciences · doi:10.7150/ijbs.7251 · Cited by 25

Blocking transient receptor potential vanilloid 2 channel in astrocytes enhances astrocyte‐mediated neuroprotection after oxygen–glucose deprivation and reoxygenation

Zhang, H., Xiao, J., Hu, Z., Xie, M., Wang, W., & He, D. (2016) · European Journal of Neuroscience · doi:10.1111/ejn.13352 · Cited by 25

Regulation and dysregulation of astrocyte activation and implications in tumor formation

Yang, C.-Z., Rahimpour, S., Yu, A., Lonser, R., & Zhuang, Z. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1274-8 · Cited by 32

Experience-dependent plasticity of visual cortical microcircuits

Medini, P. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.08.022 · Cited by 24

Involvement of Astrocytes in Mediating the Central Effects of Ghrelin

Frago, L. M., & Chowen, J. A. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18030536 · Cited by 24

Characterization of astrocytes and microglial cells in the hippocampal CA1 region after transient focal cerebral ischemia in rats treated with Ilexonin A

Zheng, G.-Y., Xu, A.-L., Ye, H., Chen, X.-D., & Jiang, Q. (2019) · Neural Regeneration Research · doi:10.4103/1673-5374.264465 · Cited by 24

Involvement of Glutamate Transporter-1 in Neuroprotection against Global Brain Ischemia-Reperfusion Injury Induced by Postconditioning in Rats

Zhang, W., Miao, Y., Zhou, S., Wang, B., Luo, Q., & Qiu, Y. (2010) · International Journal of Molecular Sciences · doi:10.3390/ijms11114407 · Cited by 23

Lesion-Induced Alterations in Astrocyte Glutamate Transporter Expression and Function in the Hippocampus

Schreiner, A. E., Berlinger, E., Langer, J., Kafitz, K. W., & Rose, C. R. (2013) · ISRN Neurology · doi:10.1155/2013/893605 · Cited by 23

Ethanol Alters the Physiology of Neuron–Glia Communication

González, A., & Salido, G. M. (2009) · International review of neurobiology · doi:10.1016/s0074-7742(09)88007-0 · Cited by 23

Vimentin Phosphorylation Is Required for Normal Cell Division of Immature Astrocytes

de Pablo, Y., Marášek, P., Pozo-Rodrigálvarez, A., Wilhelmsson, U., Inagaki, M., Pekna, M., & Pekny, M. (2019) · Cells · doi:10.3390/cells8091016 · Cited by 23

Erinacine A attenuates glutamate transporter 1 downregulation and protects against ischemic brain injury

Hsu, P.-C., Lan, Y.-J., Chen, C., Lee, L., Chen, W.-P., Wang, Y.-C., & Lee, Y. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120833 · Cited by 22

Broad spectrum proteomics analysis of the inferior colliculus following acute hydrogen sulfide exposure

Kim, D.-S., Anantharam, P., Hoffmann, A., Meade, M. L., Grobe, N., Gearhart, J. M., Whitley, E. M., Mahama, B., & Rumbeiha, W. K. (2018) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2018.06.001 · Cited by 22

Attenuation of Reactive Gliosis Does Not Affect Infarct Volume in Neonatal Hypoxic-Ischemic Brain Injury in Mice

Järlestedt, K., Rousset, C. I., Faiz, M., Wilhelmsson, U., Ståhlberg, A., Šourková, H., Pekna, M., Mallard, C. E., Hagberg, H., & Pekny, M. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010397 · Cited by 67

High Susceptibility to Cerebral Ischemia in GFAP-Null Mice

Nawashiro, H., Brenner, M., Fukui, S., Shima, K., & Hallenbeck, J. M. (2000) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-200007000-00003 · Cited by 141

Plasminogen activator inhibitor-1 mediates cerebral ischemia-induced astrocytic reactivity

Yanev, P. G., Martín-Jiménez, C., Vesga-Jiménez, D. J., Zvinys, L., Weinrich, N., Cree, M. A., Preuss, T. M., Zhang, X., & Yepes, M. (2024) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x241270445 · Cited by 9

Transient ischemia stimulates glial fibrillary acid protein and vimentin gene expression in the gerbil neocortex, striatum and hippocampus

Kindy, M. S., Bhat, A. N., & Bhat, N. R. (1992) · Molecular Brain Research · doi:10.1016/0169-328x(92)90027-9 · Cited by 94

The Two Patterns of Reactive Astrocytosis in Postischemic Rat Brain

Petito, C. K., Morgello, S., Felix, J. C., & LESSER, M. L. (1990) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1990.141 · Cited by 337