Carmeliet, Peter

Angiogenesis in cancer and other diseases

Carmeliet, P., & Jain, R. K. (2000) · Nature

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 9,070

Molecular mechanisms and clinical applications of angiogenesis

Carmeliet, P., & Jain, R. K. (2011) · Nature

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 5,467

Basic and Therapeutic Aspects of Angiogenesis

Potente, M., Gerhardt, H., & Carmeliet, P. (2011) · Cell

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 2,771

Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

Carmeliet, P., Dor, Y., Herbert, J.-M., Fukumura, D., Brusselmans, K., Dewerchin, M., Neeman, M., Bono, F., Abramovitch, R., Maxwell, P., et al. (1998) · Nature

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 2,502

PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase

D’Hulst, G., Soro-Arnaiz, I., Masschelein, E., Veys, K., Fitzgerald, G., Smeuninx, B., Kim, S., Deldicque, L., Blaauw, B., Carmeliet, P., et al. (2020) · Nature Communications

Muscle metabolism and nutritionMuscle Physiology and Disorders

Cited by 2,310

Hypoxia and inflammation

Eltzschig, H. K., & Carmeliet, P. (2011) · New England Journal of Medicine

Cancer, Hypoxia, and MetabolismImmune Response and Inflammation

Cited by 2,061

Phenotype molding of stromal cells in the lung tumor microenvironment

Lambrechts, D., Wauters, E., Boeckx, B., Aibar, S., Nittner, D., Burton, O., Bassez, A., Decaluwé, H., Pircher, A., Van den Eynde, K., et al. (2018) · Nature Medicine

Single-cell and spatial transcriptomicsCancer Immunotherapy and Biomarkers

Cited by 1,648

Common mechanisms of nerve and blood vessel wiring

Carmeliet, P., & Tessier-Lavigne, M. (2005) · Nature

Axon Guidance and Neuronal SignalingAngiogenesis and VEGF in Cancer

Cited by 1,085

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration

Oosthuyse, B., Moons, L., Storkebaum, E., Beck, H., Nuyens, D., Brusselmans, K., Dorpe, J. V., Hellings, P., Gorselink, M., Heymans, S., et al. (2001) · Nature Genetics

Amyotrophic Lateral Sclerosis ResearchAngiogenesis and VEGF in Cancer

Cited by 1,007

HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PlGF

Rolny, C., Mazzone, M., Tugues, S., Laoui, D., Johansson, I., Coulon, C., Squadrito, M. L., Segura, I., Li, X., Knevels, E., et al. (2011) · Cancer Cell

Immune cells in cancerAngiogenesis and VEGF in Cancer

Cited by 695

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

Cantelmo, A. R., Conradi, L.-C., Brajic, A., Goveia, J., Kalucka, J., Pircher, A., Chaturvedi, P., Hol, J., Thienpont, B., Teuwen, L.-A., et al. (2016) · Cancer Cell

Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism

Cited by 659

Fatty acid carbon is essential for dNTP synthesis in endothelial cells

Schoors, S., Bruning, U., Missiaen, R., Queiroz, K. C. S., Borgers, G., Elia, I., Zecchin, A., Cantelmo, A. R., Christen, S., Goveia, J., et al. (2015) · Nature

Cancer, Lipids, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 646

Tumour hypoxia causes DNA hypermethylation by reducing TET activity

Thienpont, B., Steinbacher, J., Zhao, H., D’Anna, F., Kuchnio, A., Ploumakis, A., Ghesquière, B., Van Dyck, L., Boeckx, B., Schoonjans, L., et al. (2016) · Nature

Epigenetics and DNA MethylationCancer, Hypoxia, and Metabolism

Cited by 635

Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling

Adam, J., Hatipoglu, E., O'Flaherty, L., Ternette, N., Sahgal, N., Lockstone, H., Baban, D., Nye, E., Stamp, G. W., Wolhuter, K., et al. (2011) · Cancer Cell

Genomics, phytochemicals, and oxidative stressCancer, Hypoxia, and Metabolism

Cited by 585

FOXO1 couples metabolic activity and growth state in the vascular endothelium

Wilhelm, K., Happel, K., Eelen, G., Schoors, S., Oellerich, M. F., Lim, R., Zimmermann, B., Aspalter, I. M., Franco, C. A., Boettger, T., et al. (2016) · Nature

FOXO transcription factor regulationAngiogenesis and VEGF in Cancer

Cited by 579

Protective Role of Reactive Astrocytes in Brain Ischemia

Li, L., Lundkvist, A., Andersson, D., Wilhelmsson, U., Nagai, N., Pardo, A. C., Nodin, C., Ståhlberg, A., Aprico, K., Larsson, K., et al. (2008) · Journal of Cerebral Blood Flow & Metabolism

Neuroinflammation and Neurodegeneration MechanismsAcute Ischemic Stroke Management

Cited by 505

Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis

Wenes, M., Shang, M., Di Matteo, M., Goveia, J., Martín-Pérez, R., Serneels, J., Prenen, H., Ghesquière, B., Carmeliet, P., & Mazzone, M. (2016) · Cell Metabolism

Immune cells in cancerAngiogenesis and VEGF in Cancer

Cited by 496

Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis

Angelillo-Scherrer, A., de Frutos, P. G., Aparicio, C., Melis, E., Savi, P., Lupu, F., Arnout, J., Dewerchin, M., Hoylaerts, M. F., Herbert, J.-M., et al. (2001) · Nature Medicine

Platelet Disorders and TreatmentsBlood Coagulation and Thrombosis Mechanisms

Cited by 441

Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging

Mihaylova, M. M., Cheng, C.-W., Cao, A. Q., Tripathi, S., Mana, M. D., Bauer-Rowe, K. E., Abu-Remaileh, M., Clavain, L., Erdemir, A., Lewis, C. A., et al. (2018) · Cell Stem Cell

Dietary Effects on HealthGenetics, Aging, and Longevity in Model Organisms

Cited by 428

Histamine Receptor H1–Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome

Wouters, M. M., Balemans, D., Van Wanrooy, S., Dooley, J., Cibert-Goton, V., Alpizar, Y. A., Valdez-Morales, E. E., Nasser, Y., Van Veldhoven, P. P., Vanbrabant, W., et al. (2016) · Gastroenterology

Gastrointestinal motility and disordersIon Channels and Receptors

Cited by 372

Neurovascular signalling defects in neurodegeneration

Zacchigna, S., Lambrechts, D., & Carmeliet, P. (2008) · Nature Reviews Neuroscience

Neurological Disease Mechanisms and TreatmentsAngiogenesis and VEGF in Cancer

Cited by 345

Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease

Fraisl, P., Aragonés, J., & Carmeliet, P. (2009) · Nature Reviews Drug Discovery

Cancer, Hypoxia, and MetabolismHeme Oxygenase-1 and Carbon Monoxide

Cited by 326

Role of glutamine and interlinked asparagine metabolism in vessel formation

Huang, H., Vandekeere, S., Kalucka, J., Bierhansl, L., Zecchin, A., Brüning, U., Visnagri, A., Yuldasheva, N., Goveia, J., Cruys, B., et al. (2017) · The EMBO Journal

Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism

Cited by 320

Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not?

De Bock, K., Mazzone, M., & Carmeliet, P. (2011) · Nature Reviews Clinical Oncology

Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism

Cited by 293