Sebocytes Express Functional Cathelicidin Antimicrobial Peptides and Can Act to Kill Propionibacterium Acnes
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Cathelicidin, psoriasin, dermcidin and human hBD-2 have antimicrobial properties.
“Such molecules with antimicrobial properties are cathelicidin, psoriasin, dermcidin and human hBD-2.60-62”
From Sebaceous-immunobiology is orchestrated by sebum lipids (2017) · cites this paper as [61]
Cites
Innate antimicrobial peptide protects the skin from invasive bacterial infection
Nizet, V., Ohtake, T., Lauth, X., Trowbridge, J., Rudisill, J., Dorschner, R. A., Pestonjamasp, V., Piraino, J., Huttner, K., & Gallo, R. L. (2001) · Nature · doi:10.1038/35106587 · Cited by 1,198 · see citing works
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New developments in our understanding of acne pathogenesis and treatment
Kurokawa, I., Danby, F. W., Ju, Q., Wang, X., Xiang, L. F., Xia, L., Chen, W., Nagy, I., Picardo, M., Suh, D. H., et al. (2009) · Experimental Dermatology · doi:10.1111/j.1600-0625.2009.00890.x · Cited by 584 · see citing works
Self-citationMicrobial Symbiosis with the Innate Immune Defense System of the Skin
Gallo, R. L., & Nakatsuji, T. (2011) · Journal of Investigative Dermatology · doi:10.1038/jid.2011.182 · Cited by 387 · see citing works
Self-citationCannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes
Oláh, A., Tóth, B. I., Borbíró, I., Sugawara, K., Szöllõsi, A. G., Czifra, G., Pál, B., Ambrus, L., Kloepper, J., Camera, E., et al. (2014) · Journal of Clinical Investigation · doi:10.1172/jci64628 · Cited by 268 · see citing works
Self-citationSebaceous-immunobiology is orchestrated by sebum lipids
Lovászi, M., Szegedi, A., Zouboulis, C. C., & Törőcsik, D. (2017) · Dermato-Endocrinology · doi:10.1080/19381980.2017.1375636 · Cited by 151 · see citing works
Self-citationEndogenous Antimicrobial Peptide Expression in Response to Bacterial Epidermal Colonization
Brandwein, M., Bentwich, Z., & Steinberg, D. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01637 · Cited by 39 · see citing works
- Authors
- Lee, D.-Y., Yamasaki, K., Rudsil, J., Zouboulis, C. C., Park, G. T., Yang, J.-M., & Gallo, R. L.
- Affiliations
- Samsung Medical Center (KR)
- University of California San Diego (US)
- Städtisches Klinikum Dessau (DE)
- Corresponding author
- Gallo, Richard L.
- Venue
- Journal of Investigative Dermatology
- Publisher
- Elsevier BV
- Published
- 2008-07
- Volume
- 128
- Issue
- 7
- Pages
- 1863-1866
- ISSN
- 0022-202X (ISSN-L)
- PMC
- PMC2632971
- OpenAlex
- W1987757002
- Cited by
- 157
- References
- 1
- Citations by year
- 2026: 5 · 2025: 6 · 2024: 9 · 2023: 7 · 2022: 11 · 2021: 7 · 2020: 4 · 2019: 8 · 2018: 8 · 2017: 11 · 2016: 9 · 2015: 7 · 2014: 11 · 2013: 10 · 2012: 5
- FWCI
- 12.48
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Investigative Dermatology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR052728)
- Topics
- Life Sciences › Immunology and Microbiology › Microbiology › Antimicrobial Peptides and Activities
- Health Sciences › Medicine › Dermatology › Acne and Rosacea Treatments and Effects
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Keywords
- cathelicidin, sebocytes, Propionibacterium acnes, LL-37, hCAP18, sebaceous glands, acne
- MeSH terms
- Humans, Propionibacterium acnes, RNA, Messenger, Sebaceous Glands, Receptors, Calcitriol, Antimicrobial Cationic Peptides, Cathelicidins
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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