The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
First in vivo evidence of an NMDA receptor deficit in medication-free schizophrenic patients
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In humans, altered ERK activation causes a variety of developmental disorders which have ASD-like symptoms, although the pathogenic mechanisms are not precisely understood.”
From Transient blockade of ERK phosphorylation in the critical period causes autistic phenotypes as an adult in mice (2015) · cites this paper as [27]
In the citing paper
“It was reported that ASD is common in patients with 22q11.2 deletion syndrome27.”
From Transient blockade of ERK phosphorylation in the critical period causes autistic phenotypes as an adult in mice (2015) · cites this paper as [27]
In the citing paper
“An NMDAR single-photon emission computed tomography (SPECT) study pointed to lower NMDAR activity in unmedicated patients with schizophrenia 19 , although this finding awaits confirmation with newer, more specific probes 20 .”
From Linking early-life NMDAR hypofunction and oxidative stress in schizophrenia pathogenesis (2016) · cites this paper as [19]
Citations
Cites
Statistical parametric maps in functional imaging: A general linear approach
Friston, K. J., Holmes, A. P., Worsley, K. J., Poline, J. ‐., Frith, C. D., & Frackowiak, R. S. J. (1994) · Human Brain Mapping · doi:10.1002/hbm.460020402 · Cited by 9,688
Converging Evidence of NMDA Receptor Hypofunction in the Pathophysiology of Schizophrenia
Coyle, J. T., Tsai, G. E., & GOFF, D. C. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1300.020 · Cited by 443
Takeuchi, R., Yonekura, Y., Matsuda, H., & Konishi, J. (2002) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-001-0715-z · Cited by 134
Bressan, R. A., Erlandsson, K., Stone, J. M., Mulligan, R. S., Krystal, J. H., Ell, P. J., & Pilowsky, L. S. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.03.016 · Cited by 57
Self-citationKinetic modelling of [123I]CNS 1261—a potential SPET tracer for the NMDA receptor
Erlandsson, K., Bressan, R. A., Mulligan, R. S., Gunn, R. N., Cunningham, V. J., Owens, J., Wyper, D. J., Ell, P. J., & Pilowsky, L. S. (2003) · Nuclear Medicine and Biology · doi:10.1016/s0969-8051(02)00450-x · Cited by 40
Self-citationLurito (2000) · doi:10.1002/1097-0193(200007)10:3
Research works printed but not linked: 1
- Stone J, Erlandsson K, Arstad E, Bressan RA, Teneggi V, Ell PJ et al. Schizophrenia Bull 2005; 31 (2): 446.
Cited by
Sorted by citations
Items 201–278 of 278
Okada, N., Yahata, N., Koshiyama, D., Morita, K., Sawada, K., Kanata, S., Fujikawa, S., Sugimoto, N., Toriyama, R., Masaoka, M., et al. (2024) · Molecular Psychiatry · doi:10.1038/s41380-023-02382-8 · Cited by 7
Krystal, J. H. (2020) · Nature Medicine · doi:10.1038/s41591-020-0760-4 · Cited by 5
Self-citationDetecting synaptic autoantibodies in psychoses: need for more sensitive methods
Masdeu, J. C. (2017) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000447 · Cited by 5
Toxoplasma gondii and Schizophrenia: A Relationship That Is Not Ruled Out
Sorlózano, A., & Fernández, J. G. (2016) · InTech eBooks · doi:10.5772/66018 · Cited by 4
Rice, C. A., & Stackman, R. W. (2026) · Biology · doi:10.3390/biology15030222 · Cited by 4
Imagerie cérébrale en psychiatrie : indications et résultats
Orliac, F., & Delamillieure, P. (2012) · Encyclopédie médico-chirurgicale. Psychiatrie · doi:10.1016/s0246-1072(12)60525-2 · Cited by 6
Lee, D., Seo, J., Jeong, H. C., Lee, H., & Lee, S. B. (2021) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2021.756613 · Cited by 8
Neuroimaging studies in schizophrenia: An overview of research from Asia
Narayanaswamy, J. C., Venkatasubramanian, G., & Gangadhar, B. N. (2012) · International Review of Psychiatry · doi:10.3109/09540261.2012.704872 · Cited by 4
Development of PET and SPECT Radioligands for In Vivo Imaging of NMDA Receptors
Fuchigami, T., Nakayama, M., & Magata, Y. (2020) · Springer eBooks · doi:10.1007/978-3-030-53176-8_19 · Cited by 4
Pharmacology and Neuroscience of Antipsychotic Drugs
Waddington, J. L., O’Tuathaigh, C. M. P., & Remington, G. J. (2010) · doi:10.1002/9781444327298.ch23 · Cited by 4
Dopaminergic Hypothesis of Schizophrenia: A Historical Perspective
Jučaitė, A., & Nyberg, S. (2012) · Wiley eBooks · doi:10.1002/9781118309421.ch1 · Cited by 4
Gestational MAM (Methylazoxymethanol) Administration: A Promising Animal Model for Psychosis Onset
Pen, G. L., Bellon, A., Krebs, M., & Jay, T. M. (2011) · Neuromethods · doi:10.1007/978-1-61779-157-4_2 · Cited by 3
Dugan, C., Zikopoulos, B., & Yazdanbakhsh, A. (2024) · Schizophrenia · doi:10.1038/s41537-024-00480-2 · Cited by 5
Fusar‐Poli, P., Borgwardt, S., & McGuire, P. K. (2011) · Springer eBooks · doi:10.1007/978-94-007-0837-2_20 · Cited by 3
The quest for biomarkers in Schizophrenia: from neuroimaging to machine learning
Bajouco, M., Mota, D., Coroa, M., Caldeira, S., Santos, V., & Madeira, N. G. G. F. (2017) · International Journal of Clinical Neurosciences and Mental Health · doi:10.21035/ijcnmh.2017.4(suppl.3).s03 · Cited by 3
What value do NMDA receptor antagonist models of schizophrenia have for novel drug discovery?
Adell, A. (2025) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2025.2562017 · Cited by 2
Glutamatergic Neurotransmission Abnormalities and Schizophrenia
Dwivedi, Y., & Pandey, G. N. (2011) · Springer eBooks · doi:10.1007/978-94-007-0837-2_13 · Cited by 2
Desbonnet, L. (2015) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-12-800981-9.00016-x · Cited by 3
Disinhibition of Prefrontal Cortex Neurons in Schizophrenia
Moghaddam, B., & Pehrson, A. L. (2009) · Springer eBooks · doi:10.1007/978-1-4419-0913-8_5 · Cited by 2
Clinical Effects of Mirtazapine added to First Generation Antipsychotics in Schizophrenia
Terevnikov, V. (2013) · Työväentutkimus Vuosikirja · Cited by 2
Molecular Imaging in Schizophrenia Spectrum Disorders
Klein, H., Doorduin, J., & van Berckel, B. N. (2020) · PET and SPECT in Psychiatry · doi:10.1007/978-3-642-40384-2_18
Wilner, A., & Aubé, M. (2014) · Neuropsychoanalysis · doi:10.1080/15294145.2014.973437 · Cited by 1
Autoimmune antibody-associated encephalopathy and dementia syndromes
Fredericks, C. A., & Geschwind, M. D. (2016) · Cambridge University Press eBooks · doi:10.1017/9781139924771.023 · Cited by 1
Bigdai, E. V., & Sinegubov, A. A. (2022) · BIOPHYSICS · doi:10.1134/s0006350922020026 · Cited by 1
Mosolov, S. N., Ab, S., Незнанов, Н. Г., Tochilov, V. A., Andreev, B. V., Аведисова, А. С., Bardenshteyn, L. M., Gurovich, I., Reznik, A. M., Nb, Z., et al. (2011) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-011-9455-0 · Cited by 1
Ketamine and the Dissociatives
Frohlich, J., & Horn, J. D. V. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800212-4.00060-1 · Cited by 1
Dalmau, J. O., & Graus, F. (2022) · Cambridge University Press eBooks · doi:10.1017/9781108696722.020 · Cited by 1
Beraki, S. (2008) · Figshare · Cited by 1
Developmental Consequences of N-methyl-D-aspartate Receptor Hypofunction
Milenković, M. (2011) · TSpace (University of Toronto) · Cited by 1
The use of adjuvant L-arginine in schizophrenia: A behavioural and neurochemical analysis
MacKay, M.-A. B. (2016) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3zs2kq4m · Cited by 1
Liao, J., Wulaer, B., Mizoguchi, H., Sawahata, M., Liu, Y., Dong, G., Kaibuchi, K., Ozaki, N., Nabeshima, T., Nagai, T., et al. (2022) · doi:10.22541/au.166439569.90753669/v1 · Cited by 1
Lateral Septal Circuits Govern Schizophrenia-Like Effects of Ketamine on Social BehaviorPreprint
Wang, R., Peterson, Z. J., Balasubramanian, N., Khan, K. M., Chimenti, M. S., Thedens, D. R., Nickl‐Jockschat, T., & Marcinkiewcz, C. A. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.08.08.552372 · Cited by 1
Einfluss von Polymorphismen des DAO-Gens auf Schizophrenie und den Endophänotyp Gedächtnisleistung
Seebach, J. K. (2014) · Electronic Theses of LMU Munich (Ludwig-Maximilians-Universität München) · doi:10.5282/edoc.16712
Entzündliche Veränderungen als gemeinsame Pathogenese affektiver und schizophrener Erkrankungen
Müller, N., & Schwarz, M. (2010) · Springer eBooks · doi:10.1007/978-3-211-92215-6_5
Schizophrenia: Biological Mechanisms
Perrone‐Bizzozero, N. I., & Bullock, W. M. (2008) · Wiley eBooks · doi:10.1002/9780470048672.wecb669
Fejgin, K. (2008) · Gothenburg University Publications Electronic Archive (Gothenburg University)
Fusar‐Poli, P., & McGuire, P. K. (2009) · Cambridge University Press eBooks · doi:10.1017/cbo9780511642197.020
Small Molecules that Target Schizophrenia
Martényi, F. (2009) · Wiley Encyclopedia of Chemical Biology · doi:10.1002/9780470048672.wecb685
Brealy, J. (2015) · ORCA Online Research @Cardiff (Cardiff University)
Development of Radioligands for In Vivo Imaging of NMDA Receptors
Fuchigami, T., Nakayama, M., & Magata, Y. (2014) · Springer eBooks · doi:10.1007/978-3-642-42014-6_18
Nuclear medicine in psychiatry.
Lass, P., & Sławek, J. W. (2007) · PubMed
Functional Roles of Group II Metabotropic Glutamate Receptors in the Hippocampal CA1 Network
Rosenberg, N. (2015) · Repository for Publications and Research Data (ETH Zurich) · doi:10.3929/ethz-a-010553902
Ayad, O. (2016) · uO Research (University of Ottawa) · doi:10.20381/ruor-5979
Gomes, F. V. (2016) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.17.2016.tde-05012016-224242
Drugs that Target the Glutamate Synapse: Implications for the Glutamate Hypothesis of Schizophrenia
Mielnik, C. A., & Ramsey, A. J. (2015) · Royal Society of Chemistry eBooks · doi:10.1039/9781782622499-00115
cortex by repeated administration of antipsychotic drugs.
Fumagalli, F., Frasca, A., Racagni, G., & Riva, M. A. (2008)
Mutant and Transgenic Tools in Modeling Schizophrenia
Desbonnet, L., Tomiyama, K., Koshikawa, N., O’Tuathaigh, C. M. P., & Waddington, J. L. (2009) · Neuromethods · doi:10.1007/978-1-60761-474-6_12
d-Serine Signaling and Schizophrenia
Nishikawa, T. (2016) · Springer eBooks · doi:10.1007/978-4-431-56077-7_6
Biomarkers of brain function in psychosis and their genetic basis
Ranlund, S. M. (2016) · UCL Discovery (University College London)
The Effects of Atypical Antipsychotics on Implicit Reward Learning in Schizophrenia
Bradford, L. (2015) · QSpace (Queen's University Library)
Modulation of N-methyl-D-aspartate receptors by Gαs- and Gαi/o-coupled receptors
Trepanier, C. H. (2013) · TSpace (University of Toronto)
Dissociating variations in attention with schizotypy and anxiety
Granger, K. T. (2017) · Nottingham ePrints (University of Nottingham)
Role of the NMDA receptor subunit, NR3A, in glutamatergic synapse development
Henson, M. A. (2010) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/s4z0-fd80
Skaug, K. A. (2018) · NORA - Norwegian Open Research Archives
A Preliminary Study of the Nociceptin Receptor System in Individuals with Psychosis
Khan, M. S. (2019) · TSpace (University of Toronto)
Modeling Schizophrenia in Animals
Feifel, D., & Shilling, P. D. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809468-6.00023-1
Loureiro, C. M. (2021) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.17.2021.tde-04082021-134444
D-Serine: Basic Aspects with a Focus on Psychosis
Nishikawa, T., Umino, A., & Umino, M. (2021) · Springer eBooks · doi:10.1007/978-3-319-56015-1_470-1
I disturbi cognitivi nella schizofrenia
Galluzzo, A., Carpi, E., & Crescini, A. (2013) · Springer eBooks · doi:10.1007/978-88-470-2802-9_1
Moritz, S., Krieger, E. C., Bohn, F., & Veckenstedt, R. (2017) · Springer eBooks · doi:10.1007/978-3-662-52998-0_2
University College NHS Foundation Trust and University College London (2011) · Springer eBooks · doi:10.1007/978-3-642-25123-8_25
Psychoneurobiology Research and Personalized Treatment of Schizophrenia
Sumiyoshi, T. (2022) · MDPI eBooks · doi:10.3390/books978-3-0365-2858-8
Molecular Imaging in Schizophrenia Spectrum Disorders
Klein, H. C., Doorduin, J., & van Berckel, B. N. M. (2020) · Springer eBooks · doi:10.1007/978-3-030-57231-0_16
Martényi, F. (2012) · Chemical biology · doi:10.1002/9781118435762.ch18
D-Serine: Basic Aspects with a Focus on Psychosis
Nishikawa, T., Umino, A., & Umino, M. (2022) · Springer eBooks · doi:10.1007/978-3-030-62059-2_470
Role of cryptic rearrangements of human chromosomes in the aetiology of schizophrenia
Jurisova, L., & Šolc, R. (2023) · Journal of Genetics · doi:10.1007/s12041-023-01427-9
Yang, X., & Lui, S. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-95223-1.00024-2
The Role of the Immune System in Creating Depression, Post-traumatic-Stress-Disorder, and Psychosis
Littrell, J. L. (2024) · Integrated science · doi:10.1007/978-3-031-72079-6_2
Recent Progress in NMDA Glutamate Receptor Imaging
Erlandsson, K., & Galovic, M. (2025) · Neuromethods · doi:10.1007/978-1-0716-4494-2_1
Self-citationMolecular Neuroimaging, Pathophysiological Mechanisms, and Drug Discovery
McGuire, P. K. (2009) · Springer eBooks · doi:10.1007/978-1-4419-0913-8_8
Cognitive Impairment in Schizophrenia: Neurobiological Bases
Martini, F., Spangaro, M., Sapienza, J., Bosia, M., & Cavallaro, R. (2025) · Comprehensive approach to psychiatry · doi:10.1007/978-3-032-06209-3_11
Marqueurs neurodéveloppementaux en psychiatrie : intérêt dans les troubles schizophréniques
Gay, O. (2016) · theses.fr (ABES) · doi:10.70675/b0e8f0f3ze67bz4340z9b3cz01b56b6184f0
Engel, M. (2014) · Research Online (University of Wollongong)
Metadata
- Authors
- Pilowsky, L. S., Bressan, R. A., Stone, J. M., Erlandsson, K., Mulligan, R. S., Krystal, J. H., & Ell, P. J.
- Affiliations
- King's College London (GB)
- University College London (GB)
- Yale University (US)
- Venue
- Molecular Psychiatry
- Published
- 2005-09-27
- Volume
- 11
- Issue
- 2
- Pages
- 118-119
- ISSN
- 1359-4184 (ISSN-L)
- 1476-5578
- OpenAlex
- W2066489132
- Cited by
- 278
- References
- 6
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 6 · 2023: 8 · 2022: 11 · 2021: 9 · 2020: 11 · 2019: 8 · 2018: 7 · 2017: 14 · 2016: 20 · 2015: 19 · 2014: 16 · 2013: 21 · 2012: 17
- FWCI
- 6.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Molecular Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- Funders
- National Institutes of Health (5k05aa014906-03)
- National Institute on Alcohol Abuse and Alcoholism (KO5 AA 014906-02)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- NMDA receptor, schizophrenia, medication-free patients, receptor availability, first-episode psychosis, ketamine, brain volume
- MeSH terms
- Analysis of Variance, Clozapine, Guanidines, Hippocampus, Humans, Functional Laterality, Reference Values, Schizophrenia, Tissue Distribution, Antipsychotic Agents, Tomography, Emission-Computed, Single-Photon, Case-Control Studies, Receptors, N-Methyl-D-Aspartate, Genetic Predisposition to Disease
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review