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Prevalence and Risk Factors of Carotid Plaque Among Middle-aged and Elderly Adults in Rural Tianjin, China

Zhan, Changqing, Shi, Min, Yang, Ying, Pang, Hongbo, Fei, Shizao, Bai, Lingling, Liu, Bin, Tu, Jun, Huo, Yong, Ning, Xianjia, Zhang, Yan, Wang, Jinghua·2016·Scientific Reports
DOI 10.1038/srep23870PMC PMC4814923
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Abstract

Carotid plaque (CP) is associated with cardiovascular and cerebrovascular events. However, population-based studies with a large sample are rare in China, particularly those in the low-income population. We aimed to determine the prevalence of CP and the associated risk factors in the rural areas of northern China. Between April 2014 and June 2014, we recruited 3789 residents aged ≥45 years. B-mode ultrasonography was performed to measure the extent of CP. The prevalence of CP was 40.3% overall, 47.1% in men and 35.4% in women (P < 0.001). The prevalence of CP increased with increasing age (P < 0.001). The participants with CP were more likely to have hypertension, diabetes, high total cholesterol (TC) levels and high low-density lipoprotein-cholesterol levels and be a current smoker; however, they were less likely to be obese. Multiple logistic regression analysis, adjusted for confounders, indicated that age, male sex, hypertension, diabetes, current smoking and high LDL-C levels were the independent risk factors for CP. There was a lower risk of CP with alcohol consumption. The findings suggest that managing the conventional risk factors is crucial to reduce the burden of cardiovascular and cerebrovascular diseases in the low-income population in China.

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  1. The Ministry of Health of the People’s Republic of China: China Health Statistics Yearbook 2011 (China Union Medical University Press, 2011).
  2. Murray, C. J. & Lopez, A. D. Mortality by cause for eight regions of the world: Global Burden of Disease Study. Lancet. 349, 1269–1276 (1997). · DOI · Paper page
  3. Brook, R. D. et al. A negative carotid plaque area test is superior to other non-invasive atherosclerosis studies for reducing the likelihood of having underlying significant coronary artery disease. Arterioscler Thromb Vasc Biol. 26(3), 656–662 (2006). · DOI
  4. Prabhakaran, S. et al. Carotid plaque surface irregularity predicts ischemic stroke: the northern Manhattan study. Stroke. 37(11), 2696–2701 (2006). · DOI
  5. Rubin, M. R. et al. Carotid artery plaque thickness is associated with increases serum calcium levels: the Northern Manhattan study. Atherosclerosis. 194(2), 426–432 (2007). · DOI
  6. de Weerd, M. et al. Prediction of asymptomatic carotid artery stenosis in the general population: identification of high-risk groups. Stroke. 45(8), 2366–2371 (2014). · DOI
  7. Hennerici, M. et al. Natural history of asymptomatic extracranial arterial disease. Results of a long-term prospective study. Brain. 110 (pt 3), 777–791 (1987). · DOI
  8. Inzitari, D. et al. The causes and risk of stroke in patients with asymptomatic internal-carotid-artery stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med. 342, 1693–1700 (2000). · DOI
  9. Norris, J. W., Zhu, C. Z., Bornstein, N. M. & Chambers, B. R. Vascular risks of asymptomatic carotid stenosis. Stroke. 22, 1485–1490 (1991). · DOI
  10. O’Holleran, L. W., Kennelly, M. M., McClurken, M. & Johnson, J. M. Natural history of asymptomatic carotid plaque. Five year follow-up study. Am J Surg. 154, 659–662 (1987). · DOI
  11. Cao, J. J. et al. Association of carotid artery intima-media thickness,plaques and C-reactive protein with future cardiovascular disease and all-cause mortality: the Cardiovascular Health Study. Circulation. 116, 32–38 (2007). · DOI
  12. Lorenz, M. W. et al. Carotid intima-media thickening indicates a higher vascular risk across a wide age range: prospective data from the Carotid Atherosclerosis Progression Study (CAPS). Stroke. 37, 87–92 (2006). · DOI
  13. van der Meer, I. M. et al. Predictive value of noninvasive measures of atherosclerosis for incident Myo-cardial infarction: the Rotterdam Study. Circulation. 109, 1089–1094 (2004). · DOI
  14. Kuo, F. et al. Traditional cardiovascular risk factors explain the minority of the variability in carotid plaque. Stroke. 43, 1755–1760 (2012). · DOI
  15. Spence, J. D. & Rundek, T. Toward clinical applications of carotid ultrasound: Intima-media thickness, plaque area and three-dimensional phenotypes in Ultrasound and Carotid Bifurcation Atherosclerosis (eds Nicolaides, A. E. et al. ) 431–448 (Springer-Verlag, 2012). · DOI
  16. Johnsen, S. H. et al. Carotid atherosclerosis is a stronger predictor of myocardial infarction in women than in men: A 6-year follow-up study of 6226 persons: The tromso study. Stroke. 38, 2873–2880 (2007). · DOI
  17. Inaba, Y., Chen, J. A. & Bergmann, S. R. Carotid plaque, compared with carotid intima–media thickness, more accurately predicts coronary artery disease events: A meta-analysis. Atherosclerosis. 220, 128–133 (2012). · DOI
  18. Mathiesen, E. B. et al. Carotid plaque area and intima-media thickness in prediction of first-ever ischemic stroke: A 10-year follow-up of 6584 men and women: The tromso study. Stroke. 42, 972–978 (2011). · DOI
  19. Spence, J. D. et al. Carotid plaque area: a tool for targeting and evaluating vascular preventive therapy. Stroke. 33, 2916–2922 (2002). · DOI
  20. Johnsen, S. H. & Mathiesen, E. B. Carotid plaque compared with intima-media thickness as a predictor of coronary and cerebrovascular disease. Curr Cardiol Rep. 11, 21–27 (2009). · DOI
  21. Hulthe, J. et al. Atherosclerotic changes in the carotid artery bulb as measured by B-mode ultrasound are associated with the extent of coronary atherosclerosis. Stroke. 28, 1189–1194 (1997). · DOI
  22. Rundek, T. et al. Carotid plaque, a subclinical precursor of vascular events: The Northern Manhattan Study. Neurology. 70(14), 1200–1207 (2008). · DOI
  23. Sillesen, H. et al. Carotid plaque burden as a measure of subclinical atherosclerosis: comparison with other tests for subclinicalarterial disease in the High Risk Plaque BioImage study. JACC Cardiovasc Imaging. 5(7), 681–689 (2012). · DOI
  24. Herder, M., Johnsen, S. H., Arntzen, K. A. & Mathiesen, E. B. Risk factors for progression of carotid intima-media thickness and total plaque area: a 13-year follow-up study: the Tromsø Study. Stroke. 43(7), 1818–1823 (2012). · DOI
  25. van der Meer, I. M. et al. Risk factors for progression of atherosclerosis measured at multiple sites in the arterial tree: the Rotterdam Study. Stroke. 34, 2374–2379 (2003). · DOI
  26. Chambless, L. E. et al. Risk factors for progression of common carotid atherosclerosis: the Atherosclerosis Risk in Communities Study, 1987–1998. Am J Epidemiol. 155, 38–47 (2002). · DOI
  27. Yang, D. et al. Cigarette Smoking and Carotid Plaque Echodensity in the Northern Manhattan Study. Cerebrovasc dis. 40(3–4), 136–143 (2015). · DOI
  28. Wang, W. et al. Distribution characteristics and risk factors of carotid atherosclerosis in middle-aged and elderly Chinese. Chin J Cardiol. 38, 553–557 (2010).
  29. Spence, J. D., Barnett, P. A., Bulman, D. E. & Hegele, R. A. An approach to ascertain probands with a non-traditional risk factor for carotid atherosclerosis. Atherosclerosis. 144, 429–434 (1999). · DOI
  30. Roman, M. J. et al. Preclinical carotid atherosclerosis in patients with rheumatoid arthritis. Ann Intern Med. 144(4), 249–256 (2006). · DOI
  31. Spence, J. D. & Hegele, R. A. Noninvasive phenotypes of atherosclerosis: similar windows but different views. Stroke. 35, 649–653 (2004). · DOI
  32. Delcker, A., Diener, H. C. & Wilhelm, H. Influence of vascular risk factors for atherosclerotic carotid artery plaque progression. Stroke. 26, 2016–2022 (1995). · DOI
  33. Bowden, D. W. et al. Genetic epidemiology of subclinical cardiovascular disease in the Diabetes Heart Study. Ann Hum Genet. 72, 598–610 (2008). · DOI
  34. Roman, M. J. et al. Prevalence and correlates of accelerated atherosclerosis in systemic lupus erythematosus. N Engl J Med. 349(25), 2399–2406 (2003). · DOI
  35. Furnkranz, A. et al. Oxidized phospholipids trigger atherogenic inflammation in murine arteries. Arterioscler Thromb Vasc Biol. 25(3), 633–638 (2005). · DOI
  36. Paneni, F., Beckman, J. A., Creager, M. A. & Cosentino, F. Diabetes and vascular disease: pathophysiology, clinical consequences and medical therapy: part I. Eur Heart J. 34(31), 2436–2443 (2013). · DOI
  37. Csordas, A. & Bernhard, D. The biology behind the atherothrombotic effects of cigarette smoke. Nat Rev Cardiol. 10, 219–230 (2013). · DOI
  38. Su, T. C. et al. Y.T. Hypertension status is the major determinant of carotid atherosclerosis: a community-based study in Taiwan. Stroke. 32(10), 2265–2271 (2001). · DOI · Paper page
  39. Emeson, E. E. et al. Alcohol inhibits the progression as well as the initiation of atherosclerotic lesions in C57B1/6 hyperlipidemic mice. Alcohol Clin Exp Res. 24, 1456–1466 (2000). · DOI
  40. Salaspuro, M. P. et al. Attenuation of the ethanol-induced hepatic redox change after chronic alcohol consumption in baboons: Metabolic consequences in vivo and in vitro. Hepatology. 1, 33–38 (1981). · DOI
  41. Wang, J. et al. Trends of hypertension prevalence, awareness, treatment and control in rural areas of northern China during 1991–2011. J Hum Hypertens. 28, 25–31 (2014). · DOI
  42. Wang, J. et al. Sex differences in trends of incidence and mortality of first-ever stroke in rural Tianjin, China, from 1992 to 2012. Stroke. 45, 1626–1631 (2014). · DOI
  43. Wang, J. et al. Increasing stroke incidence and prevalence of risk factors in a low-income Chinese Population. Neurology. 84, 374–381 (2015). · DOI
  44. Ning X. et al. Secular Trends in Prevalence of Overweight and Obesity among Adults in Rural Tianjin, China from 1991 to 2011: A Population-Based Study. PLOS One. 9(12), e116019 (2014). · DOI
  45. National Bureau of Statistics of China: China Statistical Yearbook (China Statistics Press, 2015).
  46. Zhou, B. F. Effect of body mass index on all-cause mortality and incidence of cardiovascular diseases–report for meta-analysis of prospective studies open optimal cut-off points of body mass index in Chinese adults. Biomed Environ Sci. 15(3), 245–252 (2002).
  47. Diabetes branch of the Chinese Medical Association. China Guidelines for Type II Diabetes Mellitus (Peking University Medical Press, 2011).
  48. Touboul, P. J. et al. Mannheim carotid intima-media thickness and plaque consensus (2004–2006–2011). An update on behalf of the advisory board of the 3rd, 4th and 5th watching the risk symposia, at the 13th, 15th and 20th European Stroke Conferences, Mannheim, Germany, 2004, Brussel, Belgium, 2006 and Hamburg, Germany, 2011. Cerebrovasc Dis. 34, 290–296 (2012). · DOI

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Metadata

Authors
Zhan, C., Shi, M., Yang, Y., Pang, H., Fei, S., Bai, L., Liu, B., Tu, J., Huo, Y., Ning, X., Zhang, Y., & Wang, J.
Venue
Scientific Reports
Publisher
Springer Science and Business Media LLC
Published
2016-03-31
Volume
6
Issue
1
ISSN
2045-2322
DOI
10.1038/srep23870
PMC
PMC4814923
Cited by
41
References
1
Language
en
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