The DOI matches its Crossref record; 112 of the 112 references it cites were found in a registry or an index.
Acetylcholinesterase inhibitors from plants and fungi
Abstract
This review describes 183 compounds obtained from plants and fungi which have been shown to inhibit acetylcholinesterase. The mechanism of action of cholinesterase, together with the binding sites, and, where this is known, the mode of action of inhibitors is described. The relative activities of the different compounds are recorded. The strongest inhibitors are generally alkaloids although some meroterpenoids from fungi have also been found to be active and display better selectivity.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The secondary metabolites of the various classes such as alkaloids, terpenoids, coumarins, flavonoids, etc. have been reported to have potent AChEinhibitory activity [71,72,73,74].”
From Acetylcholinesterase Inhibitory Potential of Various Sesquiterpene Analogues for Alzheimer’s Disease Therapy (2021) · cites this paper as [71]
Citations
Cites
A new and rapid colorimetric determination of acetylcholinesterase activity
Ellman, G. L., Courtney, K. D., Andres, V., & Featherstone, R. M. (1961) · Biochemical Pharmacology · doi:10.1016/0006-2952(61)90145-9 · Cited by 27,221
Sussman, J. L., Harel, M., Frolow, F., Oefner, C., Goldman, A., Toker, L., & Silman, I. (1991) · Science · doi:10.1126/science.1678899 · Cited by 2,740
Perry, E., Tomlinson, B. E., Blessed, G., Bergmann, K., Gibson, P., & Perry, R. H. (1978) · British medical journal · doi:10.1136/bmj.2.6150.1457 · Cited by 2,043
Crystal Structure of Human Butyrylcholinesterase and of Its Complexes with Substrate and Products
Nicolet, Y., Lockridge, O., Masson, P., Fontecilla-Camps, J. C., & Nachon, F. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210241200 · Cited by 851
Heinrich, M., & Teoh, H. L. (2004) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2004.02.012 · Cited by 587
Cholinesterase inhibitors: new roles and therapeutic alternatives
Giacobini, E. (2004) · Pharmacological Research · doi:10.1016/j.phrs.2003.11.017 · Cited by 572
Acetylcholinesterase: ‘classical’ and ‘non-classical’ functions and pharmacology
Silman, I., & Sussman, J. L. (2005) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2005.01.014 · Cited by 540
Rhee, I. K., van de Meent, M. H. M., Ingkaninan, K., & Verpoorte, R. (2001) · Journal of Chromatography A · doi:10.1016/s0021-9673(01)00624-0 · Cited by 465
Perry, N. S. L., Houghton, P. J., Theobald, A. E., Jenner, P. G., & Perry, E. K. (2000) · Journal of Pharmacy and Pharmacology · doi:10.1211/0022357001774598 · Cited by 458
Self-citation2-Pyrone natural products and mimetics: isolation, characterisation and biological activity
McGlacken, G. P., & Fairlamb, I. J. S. (2005) · Natural Product Reports · doi:10.1039/b416651p · Cited by 367
Flagged first, then by citations
Cited by
Sorted by citations
Items 301–400 of 613
Hannour, K., Boughdad, A., Maataoui, A., & Bouchelta, A. (2018) · International Journal of Tropical Insect Science · doi:10.1017/s1742758418000012 · Cited by 20
Pereira, A. F., de Castro, A. A., Soares, F. V., Leal, D. H. S., da Cunha, E. F. F., Mancini, D. T., & Ramalho, T. C. (2019) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2019.06.007 · Cited by 20
Li, H., Feng, W., Li, X., Kang, X., Yan, S., Chao, M., Mo, S., Sun, W., Lu, Y., Chen, C., et al. (2020) · Organic Letters · doi:10.1021/acs.orglett.0c02641 · Cited by 20
Adib, M., Islam, R., Ahsan, M., Rahman, A., Hossain, M., Rahman, M. M., Alshehri, S. M., Kazi, M., & Mazid, M. A. (2021) · Saudi Journal of Biological Sciences · doi:10.1016/j.sjbs.2021.03.063 · Cited by 19
Lee, J.-K. (2009) · Journal of the Korean Society for Applied Biological Chemistry · doi:10.3839/jksabc.2009.108 · Cited by 19
Evaluation of Bioactive Compounds as Acetylcholinesterase Inhibitors from Medicinal Plants
Bhadra, S., Dalai, M. K., Chanda, J., & Mukherjee, P. K. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800874-4.00013-1 · Cited by 19
In Vitro Anti‐AChE, Anti‐BuChE, and Antioxidant Activity of 12 Extracts of Eleutherococcus Species
Załuski, D., & Kuźniewski, R. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/4135135 · Cited by 19
Bourakna, Z., Righi, K., & Assia, F. R. (2022) · Journal of Essential Oil Bearing Plants · doi:10.1080/0972060x.2022.2129459 · Cited by 18
Zhou, Z., Wu, M., Sun, B., Li, J., Li, J., Liu, Z., Gao, M., Xue, L., Xu, S., & Wang, R. (2024) · Journal of Plant Physiology · doi:10.1016/j.jplph.2024.154218 · Cited by 18
Cuartero, M., García, M. S., Garcı́a-Cánovas, F., & Ortuño, J. Á. (2013) · Talanta · doi:10.1016/j.talanta.2013.03.022 · Cited by 18
Sadeghi, A., Pourya, M., & Smagghe, G. J. (2016) · Phytoparasitica · doi:10.1007/s12600-016-0551-0 · Cited by 18
First evidence of cholinesterase-like activity in Basidiomycota
Sepčić, K., Sabotič, J., Ohm, R. A., Drobne, D., & Kokalj, A. J. (2019) · PLoS ONE · doi:10.1371/journal.pone.0216077 · Cited by 18
Yu, M., Liu, S.-N., Liu, H., Meng, Q.-H., Qin, X., & Liu, H. (2021) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2021.105404 · Cited by 18
Abbad, I., Soulaimani, B., & Abbad, A. (2023) · Journal of Natural Pesticide Research · doi:10.1016/j.napere.2023.100021 · Cited by 18
Porres-Martínez, M., Accame, M. E. C., & Cuadrado, M. P. G.-S. (2013) · Lazaroa · doi:10.5209/rev_laza.2013.v34.n1.43298 · Cited by 18
NATURAL CHOLINESTERASE INHIBITORS FROM MUSHROOMS
Patočka, J. (2012) · Military Medical Science Letters · doi:10.31482/mmsl.2012.005 · Cited by 18
Khater, S., & El-Shafiey, S. N. (2015) · Egyptian Journal of Biological Pest Control · Cited by 18
Bektašević, M., Politeo, O., & Carev, I. (2021) · Chemistry & Biodiversity · doi:10.1002/cbdv.202000935 · Cited by 18
Baghazaoui, R. E., Belmalha, S., Boutagayout, A., Nassiri, L., Alami, S. E., Savoie, J., & Bouiamrine, E. H. (2024) · Agriculture · doi:10.3390/agriculture14071150 · Cited by 17
Ayres, V. F. D. S., de Oliveira, M. R., Baldin, E. L. L., Corrêa, G. M., Guimarães, A. C., & Takeara, R. (2021) · Anais da Academia Brasileira de Ciências · doi:10.1590/0001-3765202120200616 · Cited by 17
Kheloul, L., Anton, S., Bréard, D., & Kellouche, A. (2021) · Botany Letters · doi:10.1080/23818107.2021.1982767 · Cited by 19
Flavonoids as Promising Multitarget Agents in Alzheimer’s Disease Therapy
Lima, E., Rauter, A. P., & Medeiros, J. (2023) · Applied Sciences · doi:10.3390/app13084651 · Cited by 17
Qi, Y., Wang, J., Zheng, Y., Zhang, J., & Du, S. (2023) · Journal of Food Protection · doi:10.1016/j.jfp.2023.100205 · Cited by 17
M’hamdi, Z., Davì, F., Elhourri, M., Amechrouq, A., Mondello, F., Cacciola, F., Vinci, R. L., Mondello, L., Miceli, N., & Taviano, M. F. (2024) · Molecules · doi:10.3390/molecules29174036 · Cited by 17
The Genus Galanthus: A Source of Bioactive Compounds
Berkov, S. H., Codina, C. J., & Basti, J. (2012) · InTech eBooks · doi:10.5772/28798 · Cited by 17
Lopes, J. P. B., da Silva, L. A. A., Ceschi, M. A., Lüdtke, D. S., Zimmer, A. R., Ruaro, T. C., Dantas, R. F., de Salles, C. M. C., Silva, F. P., Senger, M. R., et al. (2019) · MedChemComm · doi:10.1039/c9md00358d · Cited by 17
Gupta, S., & Mohan, C. G. (2010) · Medicinal Chemistry Research · doi:10.1007/s00044-010-9373-7 · Cited by 17
Sirimangkalakitti, N., Olatunji, O. J., Changwichit, K., Saesong, T., Chamni, S., Pithi Chanvorachote, B., Ingkaninan, K., Plubrukarn, A., & Suwanborirux, K. (2015) · Natural Product Communications · doi:10.1177/1934578x1501001135 · Cited by 17
Monoterpenes alter TAR1-driven physiology in Drosophila species
Finetti, L., Tiedemann, L., Zhang, X., Civolani, S., Bernacchia, G., & Roeder, T. (2020) · Journal of Experimental Biology · doi:10.1242/jeb.232116 · Cited by 16
Malak, N., Niaz, S., Miranda-Miranda, E., Cossío-Bayúgar, R., Duque, J. E., Amaro-Estrada, I., Nasreen, N., Khan, A. N., Kulisz, J., & Zając, Z. (2024) · Experimental and Applied Acarology · doi:10.1007/s10493-024-00901-y · Cited by 16
Mentha arvensis oil exhibits repellent acute toxic and antioxidant activities in Nauphoeta cinerea
dos Santos, C. A. L., Moreira, A. M. T., Teles, B. R. D. S., Kamdem, J. P., Alasmari, A. F., Alasmari, F. F., Khan, M., Barros, L. M., & Ibrahim, M. (2024) · Scientific Reports · doi:10.1038/s41598-024-72722-3 · Cited by 16
Ma, W., Feng, J., Jiang, Z., & Zhang, X. (2014) · Journal of the American Mosquito Control Association · doi:10.2987/14-6412r.1 · Cited by 16
Dark Classics in Chemical Neuroscience: An Evidence-Based Systematic Review of Belladonna
Maurya, V. K., Kumar, S., Kabir, R., Shrivastava, G., Shanker, K., Nayak, D., Khurana, A. K., Manchanda, R. K., Gadugu, S., Kar, S. K., et al. (2020) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.0c00413 · Cited by 16
Mamun, A. A., Pidaný, F., Hulcová, D., Maříková, J., Kučera, T., Schmidt, M., Catapano, M. C., Hrabinová, M., Jun, D., Múčková, Ľ., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22158308 · Cited by 16
Safa, N., Trobec, T., Holland, D. C., Ślązak, B., Jacobsson, E., Hawkes, J. A., Frangež, R., Sepčić, K., Göransson, U., Moodie, L. W. K., et al. (2021) · Journal of Natural Products · doi:10.1021/acs.jnatprod.1c00980 · Cited by 16
Wang, F., Liu, M., Niu, X., Lian, X., & Qu, F. (2023) · Analytica Chimica Acta · doi:10.1016/j.aca.2023.340815 · Cited by 16
Ali, N. A. A., Crouch, R. A., Al-Fatimi, M., Arnold, N., Teichert, A., Setzer, W. N., & Wessjohann, L. A. (2012) · Natural Product Communications · doi:10.1177/1934578x1200700137 · Cited by 16
Metabolic and biological prospecting of Coreopsis tinctoria
Gaspar, L., Oliveira, A. P., Silva, L. R., Andrade, P. B., de Pinho, P. G., Botelho, J., & Valentão, P. (2011) · Revista Brasileira de Farmacognosia · doi:10.1590/s0102-695x2011005000224 · Cited by 16
Centaurea rupestris L.: Cytogenetics, Essential Oil Chemistry and Biological Activity
Carev, I., Maravić, A., Bektašević, M., Ruščić, M., Šiljak-Yakovlev, S., & Politeo, O. (2018) · Croatica Chemica Acta · doi:10.5562/cca3205 · Cited by 16
Vilela, A. F. L., Seidl, C., Lima, J. M., & Cardoso, C. L. (2018) · Analytical Biochemistry · doi:10.1016/j.ab.2018.03.012 · Cited by 16
Myristica fragrans Houtt.: Botanical, Pharmacological, and Toxicological Aspects
Arumugam, G., Purushotham, B., & Swamy, M. K. (2019) · Springer eBooks · doi:10.1007/978-981-13-7205-6_4 · Cited by 16
McNulty, J., Nair, J. J., Singh, M., Crankshaw, D., & Holloway, A. C. (2009) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2009.08.032 · Cited by 16
Boswellic Acids with Acetylcholinesterase Inhibitory Properties from Frankincense
Ota, M., & Houghton, P. J. (2008) · Natural Product Communications · doi:10.1177/1934578x0800300105 · Cited by 16
Self-citationCytochrome P450 3A4 Inhibitory Activity Studies within the Lycorine series of Alkaloids
McNulty, J., Nair, J. J., Singh, M., Crankshaw, D., Holloway, A. C., & Bastida, J. (2010) · Natural Product Communications · doi:10.1177/1934578x1000500809 · Cited by 15
Acetylcholinesterase affinity-based screening assay on Lippia gracilis Schauer extracts
Vanzolini, K. L., Sprenger, R. D. F., Leme, G. M., Moraes, V. R. D. S., Vilela, A. F. L., Cardoso, C. L., & Cass, Q. B. (2018) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2018.02.035 · Cited by 15
Chiluwal, K., Lee, B., Kwon, T. H., Kim, J., Bae, S. D., Roh, G. H., Ren, Y., Li, B., & Park, C. G. (2020) · Journal of Asia-Pacific Entomology · doi:10.1016/j.aspen.2020.03.010 · Cited by 15
Self-citationLiu, S., Dang, M., Lei, Y., Ahmad, S. S., Khalid, M., Kamal, M. A., & Chen, L. (2020) · Current Pharmaceutical Design · doi:10.2174/1381612826666200407161842 · Cited by 15
Mahmoodi, L., Valizadegan, O., & Mahdavi, V. (2014) · Journal of Plant Protection Research · doi:10.2478/jppr-2014-0044 · Cited by 15
Dincheva, I. N., Badjakov, I. K., Georgiev, V., Semerdjieva, I. B., Vrancheva, R. Z., Ivanov, I. G., & Pavlov, A. I. (2025) · Plants · doi:10.3390/plants14020270 · Cited by 14
Isolation and Cholinesterase Activity of Amaryllidaceae Alkaloids from Nerine bowdenii
Cahlíková, L., Zavadil, S., Macáková, K., Valterová, I., Kulhánková, A., Hošťálková, A., Kuneš, J., & Opletal, L. (2011) · Natural Product Communications · doi:10.1177/1934578x1100601210 · Cited by 14
Dai, W., Sandoval, I. T., Cai, S., Smith, K., Delacruz, R. G. C., Boyd, K. A., Mills, J. J., Jones, D. A., & Cichewicz, R. H. (2019) · Journal of Natural Products · doi:10.1021/acs.jnatprod.9b00563 · Cited by 14
Monarda didyma Hydrolate Affects the Survival and the Behaviour of Drosophila suzukii
Finetti, L., Civolani, S., Mirandola, D., Benetti, L., Francati, S., Albanese, F., Menicucci, F., Michelozzi, M., Bellardi, M. G., Dindo, M. L., et al. (2022) · Insects · doi:10.3390/insects13030280 · Cited by 15
Zhao, N., Liu, D., Wang, Y., Zhang, X., & Zhang, L. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.115641 · Cited by 14
Li, S., Huang, R., Solomon, S., Liu, Y., Zhao, B., Santillo, M. F., & Xia, M. (2017) · Biotechnology Journal · doi:10.1002/biot.201600715 · Cited by 14
Arshad, A. S. M., Chear, N. J., Ezzat, M. O., Hanapi, N. A., Meesala, R., Suhana Arshad, B., Mansor, S. M., & Mordi, M. N. (2019) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2019.127070 · Cited by 14
Wang, A., Zhao, S., Gu, G., Xu, D. Q., Zhang, X., Lai, D., & Zhou, L. (2020) · RSC Advances · doi:10.1039/d0ra05022a · Cited by 14
Jyothi, P., & Yellamma, K. (2016) · International Journal of Pharmacy and Pharmaceutical Sciences · doi:10.22159/ijpps.2016v8i12.14833 · Cited by 14
Zhao, J., Xu, Z., Gao, P., & Liu, X. (2023) · Biomolecules · doi:10.3390/biom13071089 · Cited by 13
Alkaloids and Drug Discovery for Neurodegenerative Diseases
Howes, M. R. (2013) · Springer eBooks · doi:10.1007/978-3-642-22144-6_43 · Cited by 13
Self-citationSuciati, S., Poerwantoro, D., Widyawaruyanti, A., & Ingkaninan, K. (2021) · Journal of Basic and Clinical Physiology and Pharmacology · doi:10.1515/jbcpp-2020-0401 · Cited by 13
Cholinergic Component of Autism Spectrum Disorder
Mukaetova‐Ladinska, E. B., Westwood, J., & Perry, E. K. (2010) · Springer eBooks · doi:10.1007/978-1-4419-1272-5_9 · Cited by 13
Antioxidant Activities and Acetylcholinesterase Inhibitory Activities from Seaweed Extracts
전영은, 윤성복, Lim, S. S., Chung, C., & Kang, I. (2012) · Journal of the Korean Society of Food Science and Nutrition · doi:10.3746/jkfn.2012.41.4.443 · Cited by 13
Anti-Acetylcholinesterase Activity of Piper sarmentosum by a Continuous Immobilized-enzyme Assay
Khan, M. Y., Elhussein, S. A. A., Khan, M. M., & Khan, N. (2012) · APCBEE Procedia · doi:10.1016/j.apcbee.2012.06.035 · Cited by 13
Moon, U. R., Sircar, D., Barthwal, R., Sen, S. K., Beuerle, T., Beerhues, L., & Mitra, A. (2015) · Journal of Natural Medicines · doi:10.1007/s11418-015-0904-x · Cited by 13
Cahlíková, L., Kulhánková, A., Urbanová, K., Valterová, I., Macáková, K., & Kuneš, J. (2010) · Natural Product Communications · doi:10.1177/1934578x1000500810 · Cited by 13
Beri, V., Wildman, S. A., Shiomi, K., Al-Rashid, Z. F., Cheung, J., & Rosenberry, T. L. (2013) · Biochemistry · doi:10.1021/bi401043w · Cited by 13
Kim, J., Jang, M., Lee, K., Yoon, K. A., & Park, C. G. (2016) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.6b01528 · Cited by 13
Darabi, K., & Khajehali, J. (2017) · Journal of Essential Oil Bearing Plants · doi:10.1080/0972060x.2017.1358674 · Cited by 13
Synthesis of 5,6-dihydrophenanthridines via N,O-acetal TMS ethers
Lee, W., Jung, J., Jang, J., Yun, H., & Suh, Y. (2013) · Tetrahedron Letters · doi:10.1016/j.tetlet.2013.07.037 · Cited by 13
Murray, A. P., Gurovic, M. S. V., Rodriguez, S. A., Murray, M. G., & Ferrero, A. A. (2009) · Natural Product Communications · doi:10.1177/1934578x0900400628 · Cited by 13
Norouzy, A., Habibi-Rezaei, M., Qujeq, D., Vatani, M., & Badiei, A. (2010) · Bulletin of the Korean Chemical Society · doi:10.5012/bkcs.2010.31.01.157 · Cited by 13
Exploring Lamiaceae-derived bioactive compounds as nature’s arsenal for sustainable pest management
Ali, M., Muhammad, A., Lin, Z., He, H., & Zhang, Y. (2024) · Phytochemistry Reviews · doi:10.1007/s11101-024-09987-z · Cited by 12
Kamonolol acetate from Ferula pseudalliacea as AChE inhibitor: in vitro and in silico studies
Dastan, D., Validi, S., & Ebadi, A. (2020) · Structural Chemistry · doi:10.1007/s11224-019-01473-z · Cited by 12
Havlasová, J., Šafratová, M., Siatka, T., Štěpánková, Š., Novák, Z., Ločárek, M., Opletal, L., Hrabinová, M., Jun, D., Benešová, N., et al. (2014) · Natural Product Communications · doi:10.1177/1934578x1400900823 · Cited by 12
Hussein, B. A., Karimi, I., & Yousofvand, N. (2019) · In Silico Pharmacology · doi:10.1007/s40203-019-0052-1 · Cited by 12
Gussem, E. D., Tehrani, K. A., Herrebout, W., Bultinck, P., & Johannessen, C. (2019) · ACS Omega · doi:10.1021/acsomega.9b02108 · Cited by 12
Gypsogenin Derivatives: An Unexpected Class of Inhibitors of Cholinesterases
Heller, L., Schwarz, Š., Weber, B., & Csük, R. (2014) · Archiv der Pharmazie · doi:10.1002/ardp.201400103 · Cited by 12
GC/MS Analysis of Three Amaryllidaceae Species and Their Cholinesterase Activity
Cahlíková, L., Benešová, N., Macáková, K., Urbanová, K., & Opletal, L. (2011) · Natural Product Communications · doi:10.1177/1934578x1100600912 · Cited by 12
Cheung, J., Beri, V., Shiomi, K., & Rosenberry, T. L. (2014) · Journal of Molecular Neuroscience · doi:10.1007/s12031-014-0261-3 · Cited by 11
Breiterova, K. H., Ločárek, M., Kohelová, E., Talácková, M., Hulcová, D., Opletal, L., & Cahlíková, L. (2018) · Natural Product Communications · doi:10.1177/1934578x1801300410 · Cited by 11
Jiang, M., Guo, H., Wu, Q., Yuan, S., & Liu, L. (2022) · Molecules · doi:10.3390/molecules27165076 · Cited by 11
Haist, G., Sidjimova, B., Yankova-Tsvetkova, Е., Nikolova, M. T., Denev, R., Semerdjieva, I. B., Bastida, J., & Berkov, S. H. (2024) · Journal of Plant Physiology · doi:10.1016/j.jplph.2024.154223 · Cited by 11
In Vivo Cytotoxicity Studies of Amaryllidaceae Alkaloids
Nair, J. J., Bastida, J., & Staden, J. V. (2016) · Natural Product Communications · doi:10.1177/1934578x1601100134 · Cited by 11
Alkaloids from Some Amaryllidaceae Species and Their Cholinesterase Activity
Cahlíková, L., Benešová, N., Macáková, K., Kučera, R., Hrstka, V., Klimeš, J., Jahodář, L., & Opletal, L. (2012) · Natural Product Communications · doi:10.1177/1934578x1200700506 · Cited by 11
Alkaloid profiles and acetylcholinesterase inhibitory activities of Fumaria species from Bulgaria
Vrancheva, R. Z., Ivanov, I. G., Aneva, I. Y., Dincheva, I. N., Badjakov, I. K., & Pavlov, A. I. (2016) · Zeitschrift für Naturforschung C · doi:10.1515/znc-2014-4179 · Cited by 11
Mode of action of 3-butylidene phthalide as a competent natural pesticide
Abbod, M., Safaie, N., Gholivand, K., Mehrabadi, M., & Bonsaii, M. (2020) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2020.02.003 · Cited by 11
Acetylcholinesterase inhibition effects of marine fungi
Liu, Y.-W., Shi, D., Chen, A.-J., Zhu, Q., Xu, J., & Zhang, X. (2013) · Pharmaceutical Biology · doi:10.3109/13880209.2013.850516 · Cited by 11
Polyhydroxyserratane triterpenoids from Diphasiastrum complanatum
Yan, J., Yi, P., Chen, B., Lu, L., Li, Z., Zhang, X., Zhou, L., & Qiu, M. (2007) · Phytochemistry · doi:10.1016/j.phytochem.2007.07.024 · Cited by 11
Computational Approaches for Therapeutic Application of Natural Products in Alzheimer’s Disease
Awasthi, M., Singh, S., Tiwari, S., Pandey, V. P., & Dwivedi, U. N. (2017) · Neuromethods · doi:10.1007/978-1-4939-7404-7_17 · Cited by 11
Triterpenes from Warszewiczia coccinea (Rubiaceae) as Inhibitors of Acetylcholinesterase
Calderón, Á. I., Simithy, J., Quaggio, G., Espinosa, A., López‐Pérez, J. L., & Gupta, M. P. (2009) · Natural Product Communications · doi:10.1177/1934578x0900401002 · Cited by 11
NPC Natural Product Communications
Khana, S. I., Hester, J. P., Tekwania, B. L., Midiwob, J. O., Muhammada, I., Jaina, S. K., Jacoba, M. R., Walkera, L. A., Rahmana, A. A., & Samoylenkoa, V. (2011) · Cited by 11
Abderrezag, N., Sánchez-Martínez, J. D., Louaer, O., Méniai, A.-H., & Mendiola, J. A. (2021) · Molecules · doi:10.3390/molecules26226951 · Cited by 10
Dai, L., Miao, X., Li, B., Zhang, J., Pan, H., & Shang, X. (2020) · Veterinary Parasitology · doi:10.1016/j.vetpar.2020.109247 · Cited by 10
Debnath, M., Das, S., Bhowmick, S., Karak, S., Saha, A., & De, B. (2021) · Free Radicals and Antioxidants · doi:10.5530/fra.2021.1.3 · Cited by 10
Ka, S., Mérindol, N., Seck, I., Ricard, S., Diop, A., Boye, C. S. B., Landelouci, K., Daoust, B., Berthoux, L., Pépin, G., et al. (2021) · Molecules · doi:10.3390/molecules26237382 · Cited by 12
Evidente, A. (2023) · Molecules · doi:10.3390/molecules28104055 · Cited by 10
Pandır, D., & Baş, H. (2016) · Turkish Journal of Entomology · doi:10.16970/ted.82833 · Cited by 10
Ejsmond, M. J., & Provenza, F. D. (2018) · Ecosphere · doi:10.1002/ecs2.2129 · Cited by 10
Mesquita, R. D. S., Kyrylchuk, A. A., de Oliveira, R. C., Sá, I. S. C., Camargo, G. B. C., Pontes, G. S., da Silva, F. M. A., Nunomura, R. D. C. S., & Grafov, A. (2020) · PLoS ONE · doi:10.1371/journal.pone.0239364 · Cited by 10
Antioxidant Capacities and Acetylcholinesterase-inhibitory Activity ofHoppea fastigiata
Moon, U. R., Sen, S. K., & Mitra, A. (2014) · Journal of Herbs Spices & Medicinal Plants · doi:10.1080/10496475.2013.840711 · Cited by 10
Metadata
- Authors
- Houghton, P. J., Ren, Y., & Howes, M.-J.
- Affiliations
- King's College London (GB)
- Royal Botanic Gardens, Kew (GB)
- Corresponding author
- Houghton, Peter J.
- Venue
- Natural Product Reports
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2006
- Volume
- 23
- Issue
- 2
- Pages
- 181
- ISSN
- 0265-0568 (ISSN-L)
- 1460-4752
- OpenAlex
- W2126399705
- Cited by
- 584
- References
- 112
- Citations by year
- 2026: 8 · 2025: 26 · 2024: 29 · 2023: 31 · 2022: 39 · 2021: 38 · 2020: 30 · 2019: 30 · 2018: 35 · 2017: 29 · 2016: 41 · 2015: 33 · 2014: 35 · 2013: 37 · 2012: 21
- FWCI
- 2.30
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Natural Product Reports (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (King's College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Cholinesterase and Neurodegenerative Diseases
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Drug Discovery › Bioactive natural compounds
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
- Keywords
- acetylcholinesterase inhibitors, plant natural products, fungal natural products, alkaloids, meroterpenoids, binding sites, enzyme selectivity, bioactive compounds
- MeSH terms
- Biological Products, Cholinesterase Inhibitors, Fungi, Plants, Medicinal, Molecular Structure
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review